Intracellular Cryptococcus neoformans disrupts the transcriptome profile of M1- and M2-polarized host macrophages

Hacking the host: exploitation of macrophage polarization by intracellular bacterial pathogens

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Inflammatory monocytes are detrimental to the host immune response during acute infection with Cryptococcus neoformans

(2019) Lena J. Heung et al.   PLoS Pathogens

The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion

(2019) Yu Xia et al.   Autophagy

Macrophage-Derived Protein S Facilitates Apoptotic Polymorphonuclear Cell Clearance by Resolution Phase Macrophages and Supports Their Reprogramming

(2018) Delphine Lumbroso et al.   Frontiers in Immunology

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Ensembl 2019

(2018) Fiona Cunningham et al.   NUCLEIC ACIDS RESEARCH

Cryptococcus neoformans and Cryptococcus gattii clinical isolates from Thailand display diverse phenotypic interactions with macrophages

(2018) Adithap Hansakon et al.   Virulence

IFN-γ immune priming of macrophages in vivo induces prolonged STAT1 binding and protection against Cryptococcus neoformans

(2018) Chrissy M. Leopold Wager et al.   PLoS Pathogens

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis

(2017) Nuria Andreu et al.   Scientific Reports

Heme oxygenase 1 controls early innate immune response of macrophages toSalmonellaTyphimurium infection

(2016) Anna-Maria Mitterstiller et al.   CELLULAR MICROBIOLOGY

Modulation of Macrophage Inflammatory Nuclear Factor κB (NF-κB) Signaling by IntracellularCryptococcus neoformans

(2016) James B. Hayes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update

(2016) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

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(2016) Nirav Merchant et al.   PLOS BIOLOGY

Cryptococcus Neoformans Infection and Immune Cell Regulation in Human Monocytes

(2015) Sunxiao Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

STAT1 Signaling within Macrophages Is Required for Antifungal Activity against Cryptococcus neoformans

(2015) Chrissy M. Leopold Wager et al.   INFECTION AND IMMUNITY

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium

(2015) Shabarinath Srikumar et al.   PLoS Pathogens

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

A unique role for p53 in the regulation of M2 macrophage polarization

(2014) L Li et al.   CELL DEATH AND DIFFERENTIATION

STAT1 Signaling Is Essential for Protection againstCryptococcus neoformansInfection in Mice

(2014) Chrissy M. Leopold Wager et al.   JOURNAL OF IMMUNOLOGY

Heme Oxygenase-1 Dysregulates Macrophage Polarization and the Immune Response toHelicobacter pylori

(2014) Alain P. Gobert et al.   JOURNAL OF IMMUNOLOGY

The Cryptococcus neoformans Transcriptome at the Site of Human Meningitis

(2014) Y. Chen et al.   mBio

Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation

(2014) Guilhem Janbon et al.   PLoS Genetics

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

(2014) Meera Rath et al.   Frontiers in Immunology

TXNIP interacts with hEcd to increase p53 stability and activity

(2013) Hyun-Woo Suh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

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(2013) Y. Liao et al.   BIOINFORMATICS

TXNIP Maintains the Hematopoietic Cell Pool by Switching the Function of p53 under Oxidative Stress

(2013) Haiyoung Jung et al.   Cell Metabolism

Abrogation of IL-4 receptor-α-dependent alternatively activated macrophages is sufficient to confer resistance against pulmonary cryptococcosis despite an ongoing Th2 response

(2013) Uwe Müller et al.   INTERNATIONAL IMMUNOLOGY

Shaping the Murine Macrophage Phenotype: IL-4 and Cyclic AMP Synergistically Activate the Arginase I Promoter

(2013) K. E. Sheldon et al.   JOURNAL OF IMMUNOLOGY

Thioredoxin-Interacting Protein Gene Expression via MondoA Is Rapidly and Transiently Suppressed during Inflammatory Responses

(2013) Yasuyoshi Kanari et al.   PLoS One

Macrophage M1/M2 Polarization Dynamically Adapts to Changes in Cytokine Microenvironments in Cryptococcus neoformans Infection

(2013) M. J. Davis et al.   mBio

TXNIP Deficiency Exacerbates Endotoxic Shock via the Induction of Excessive Nitric Oxide Synthesis

(2013) Young-Jun Park et al.   PLoS Pathogens

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Cryptococcusinteractions with macrophages: evasion and manipulation of the phagosome by a fungal pathogen

(2012) Simon A. Johnston et al.   CELLULAR MICROBIOLOGY

A Purified Capsular Polysaccharide Markedly Inhibits Inflammatory Response during Endotoxic Shock

(2012) M. Piccioni et al.   INFECTION AND IMMUNITY

Protective Immunity against Pulmonary Cryptococcosis Is Associated with STAT1-Mediated Classical Macrophage Activation

(2012) S. E. Hardison et al.   JOURNAL OF IMMUNOLOGY

Aspergillus fumigatusmitochondrial electron transport chain mediates oxidative stress homeostasis, hypoxia responses and fungal pathogenesis

(2012) Nora Grahl et al.   MOLECULAR MICROBIOLOGY

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

High-Resolution Transcriptome of Human Macrophages

(2012) Marc Beyer et al.   PLoS One

Fungal-Induced Cell Cycle Impairment, Chromosome Instability and Apoptosis via Differential Activation of NF-κB

(2012) Mariem Ben-Abdallah et al.   PLoS Pathogens

Effect of Cytokine Interplay on Macrophage Polarization during Chronic Pulmonary Infection with Cryptococcus neoformans

(2011) Shikha Arora et al.   INFECTION AND IMMUNITY

SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformans

(2011) Methee Chayakulkeeree et al.   MOLECULAR MICROBIOLOGY

Contributions of the MyD88-Dependent Receptors IL-18R, IL-1R, and TLR9 to Host Defenses following Pulmonary Challenge with Cryptococcus neoformans

(2011) Jennifer P. Wang et al.   PLoS One

Nonlytic Exocytosis of Cryptococcus neoformans from Macrophages Occurs In Vivo and Is Influenced by Phagosomal pH

(2011) A. M. Nicola et al.   mBio

Pulmonary Infection with an Interferon-γ-Producing Cryptococcus neoformans Strain Results in Classical Macrophage Activation and Protection

(2010) Sarah E. Hardison et al.   AMERICAN JOURNAL OF PATHOLOGY

Immunomodulatory Effects of Serotype B Glucuronoxylomannan from Cryptococcus gattii Correlate with Polysaccharide Diameter

(2010) F. L. Fonseca et al.   INFECTION AND IMMUNITY

Negative Feedback Regulation of NF- B Action by CITED2 in the Nucleus

(2010) X. Lou et al.   JOURNAL OF IMMUNOLOGY

Glucose Controls Nuclear Accumulation, Promoter Binding, and Transcriptional Activity of the MondoA-Mlx Heterodimer

(2010) C. W. Peterson et al.   MOLECULAR AND CELLULAR BIOLOGY

Robust Th1 and Th17 Immunity Supports Pulmonary Clearance but Cannot Prevent Systemic Dissemination of Highly Virulent Cryptococcus neoformans H99

(2009) Yanmei Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Cryptococcal Urease Promotes the Accumulation of Immature Dendritic Cells and a Non-Protective T2 Immune Response within the Lung

(2009) John J. Osterholzer et al.   AMERICAN JOURNAL OF PATHOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Innate immune responses of primary murine macrophage-lineage cells and RAW 264.7 cells to ligands of Toll-like receptors 2, 3, and 4

(2009) Londa J. Berghaus et al.   COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

Role of Dendritic Cells and Alveolar Macrophages in Regulating Early Host Defense against Pulmonary Infection with Cryptococcus neoformans

(2009) J. J. Osterholzer et al.   INFECTION AND IMMUNITY

Cytokine Signaling Regulates the Outcome of Intracellular Macrophage Parasitism by Cryptococcus neoformans

(2009) K. Voelz et al.   INFECTION AND IMMUNITY

Th2 but Not Th1 Immune Bias Results in Altered Lung Functions in a Murine Model of Pulmonary Cryptococcus neoformans Infection

(2009) A. V. Jain et al.   INFECTION AND IMMUNITY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Cryptococcus neoformans inhibits nitric oxide synthesis caused by CpG-oligodeoxynucleotide-stimulated macrophages in a fashion independent of capsular polysaccharides

(2008) Gang Xiao et al.   MICROBIOLOGY AND IMMUNOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark