TXNIP Deficiency Exacerbates Endotoxic Shock via the Induction of Excessive Nitric Oxide Synthesis

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Thioredoxin-Interacting Protein Gene Expression via MondoA Is Rapidly and Transiently Suppressed during Inflammatory Responses

(2013) Yasuyoshi Kanari et al.   PLoS One

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

(2012) Alana G. Lerner et al.   Cell Metabolism

Cutting Edge: Nitric Oxide Inhibits the NLRP3 Inflammasome

(2012) E. Hernandez-Cuellar et al.   JOURNAL OF IMMUNOLOGY

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β

(2012) Bibhuti B Mishra et al.   NATURE IMMUNOLOGY

Evolutionary Conserved Regulation of HIF-1β by NF-κB

(2011) Patrick van Uden et al.   PLoS Genetics

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Nonconventional Initiation Complex Assembly by STAT and NF-κB Transcription Factors Regulates Nitric Oxide Synthase Expression

(2010) Matthias Farlik et al.   IMMUNITY

The SPRY domain–containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation

(2010) Zhihe Kuang et al.   JOURNAL OF CELL BIOLOGY

Vitamin D3 Upregulated Protein 1 Suppresses TNF- -Induced NF- B Activation in Hepatocarcinogenesis

(2010) H.-J. Kwon et al.   JOURNAL OF IMMUNOLOGY

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

(2010) Seth L Masters et al.   NATURE IMMUNOLOGY

Anti-oxidative, anti-cancer and anti-inflammatory actions by thioredoxin 1 and thioredoxin-binding protein-2

(2010) Rie Watanabe et al.   PHARMACOLOGY & THERAPEUTICS

Thioredoxin-interacting Protein (Txnip) Is a Feedback Regulator ofS-Nitrosylation

(2009) Michael T. Forrester et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

(2009) Akihiro Kimura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thioredoxin-Interacting Protein Regulates Hematopoietic Stem Cell Quiescence and Mobilization under Stress Conditions

(2009) M. Jeong et al.   JOURNAL OF IMMUNOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Thioredoxin Binding Protein-2/Thioredoxin-Interacting Protein Is a Critical Regulator of Insulin Secretion and Peroxisome Proliferator-Activated Receptor Function

(2008) Shin-ichi Oka et al.   ENDOCRINOLOGY

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics

(2008) Jon O. Lundberg et al.   NATURE REVIEWS DRUG DISCOVERY

PAI-1 inhibits neutrophil efferocytosis

(2008) Y.-J. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VDUP1 mediates nuclear export of HIF1α via CRM1-dependent pathway

(2007) Daesung Shin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH