IFN-γ immune priming of macrophages in vivo induces prolonged STAT1 binding and protection against Cryptococcus neoformans

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

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BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis

(2018) Eva Kaufmann et al.   CELL

Metabolic Induction of Trained Immunity through the Mevalonate Pathway

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BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity

(2018) Rob J.W. Arts et al.   Cell Host & Microbe

A Call to Arms: Quest for a Cryptococcal Vaccine

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Induction of Broad-Spectrum Protective Immunity against Disparate Cryptococcus Serotypes

(2017) Marley C. Caballero Van Dyke et al.   Frontiers in Immunology

Dectin-3 Is Not Required for Protection against Cryptococcus neoformans Infection

(2017) Althea Campuzano et al.   PLoS One

Molecular control of activation and priming in macrophages

(2016) Christopher K Glass et al.   NATURE IMMUNOLOGY

Defective trained immunity in patients with STAT-1-dependent chronic mucocutaneaous candidiasis

(2015) D. C. Ifrim et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

STAT1 Signaling within Macrophages Is Required for Antifungal Activity against Cryptococcus neoformans

(2015) Chrissy M. Leopold Wager et al.   INFECTION AND IMMUNITY

Trained innate immunity as underlying mechanism for the long-term, nonspecific effects of vaccines

(2015) Bastiaan A. Blok et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Trained immunity: A smart way to enhance innate immune defence

(2015) Jos W.M. van der Meer et al.   MOLECULAR IMMUNOLOGY

Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

(2015) Xiaodi Su et al.   NATURE IMMUNOLOGY

Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts

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STAT1 deficiency redirects IFN signalling toward suppression of TLR response through a feedback activation of STAT3

(2015) Hun Sik Kim et al.   Scientific Reports

Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex

(2015) Sebastian Wienerroither et al.   Cell Reports

Innate immune memory: towards a better understanding of host defense mechanisms

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STAT1 Signaling Is Essential for Protection againstCryptococcus neoformansInfection in Mice

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Classical versus alternative macrophage activation: the Ying and the Yang in host defense against pulmonary fungal infections

(2014) C M Leopold Wager et al.   Mucosal Immunology

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

A neglected epidemic: fungal infections in HIV/AIDS

(2014) Darius Armstrong-James et al.   TRENDS IN MICROBIOLOGY

An Opportunistic Infection Associated With Ruxolitinib, a Novel Janus Kinase 1,2 Inhibitor

(2013) Nicholas G. Wysham et al.   CHEST

Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling

(2013) Yu Qiao et al.   IMMUNITY

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Cytokine Induced Phenotypic and Epigenetic Signatures Are Key to Establishing Specific Macrophage Phenotypes

(2013) Nicolai A. Kittan et al.   PLoS One

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Protective Immunity against Pulmonary Cryptococcosis Is Associated with STAT1-Mediated Classical Macrophage Activation

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Trained Immunity: A Memory for Innate Host Defense

(2011) Mihai G. Netea et al.   Cell Host & Microbe

Protective Immunity against Experimental Pulmonary Cryptococcosis in T Cell-Depleted Mice

(2011) Karen L. Wozniak et al.   Clinical and Vaccine Immunology

The contribution of epigenetic memory to immunologic memory

(2011) Valerie P Zediak et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Epigenetic control of macrophage polarization

(2011) Osamu Takeuch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of Cytokine Interplay on Macrophage Polarization during Chronic Pulmonary Infection with Cryptococcus neoformans

(2011) Shikha Arora et al.   INFECTION AND IMMUNITY

Internal standard-based analysis of microarray data2—Analysis of functional associations between HVE-genes

(2011) Igor M. Dozmorov et al.   NUCLEIC ACIDS RESEARCH

Pulmonary Infection with an Interferon-γ-Producing Cryptococcus neoformans Strain Results in Classical Macrophage Activation and Protection

(2010) Sarah E. Hardison et al.   AMERICAN JOURNAL OF PATHOLOGY

Interferon-γ reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages

(2009) Dorothée Duluc et al.   INTERNATIONAL JOURNAL OF CANCER

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Internal standard-based analysis of microarray data. Part 1: analysis of differential gene expressions

(2009) I. Dozmorov et al.   NUCLEIC ACIDS RESEARCH

Insights into the Mechanisms of Protective Immunity against Cryptococcus neoformans Infection Using a Mouse Model of Pulmonary Cryptococcosis

(2009) Karen L. Wozniak et al.   PLoS One

A proteomic-based approach for the identification of immunodominant Cryptococcus neoformans proteins

(2009) Mattie Young et al.   PROTEOMICS