Heme oxygenase 1 controls early innate immune response of macrophages toSalmonellaTyphimurium infection

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

(2015) Manfred Nairz et al.   Cell Host & Microbe

Hepcidin-Induced Hypoferremia Is a Critical Host Defense Mechanism against the Siderophilic Bacterium Vibrio vulnificus

(2015) João Arezes et al.   Cell Host & Microbe

The Iron age of host-microbe interactions

(2015) M. P. Soares et al.   EMBO REPORTS

Heme as a danger molecule in pathogen recognition

(2015) Barbara Wegiel et al.   FREE RADICAL BIOLOGY AND MEDICINE

Macrophage defense mechanisms against intracellular bacteria

(2015) Günter Weiss et al.   IMMUNOLOGICAL REVIEWS

Contrasting regulation of macrophage iron homeostasis in response to infection with Listeria monocytogenes depending on localization of bacteria

(2015) David Haschka et al.   Metallomics

Induction of heme oxygenase-1 contributes to survival of Mycobacterium abscessus in human macrophages-like THP-1 cells

(2015) Maher Y. Abdalla et al.   Redox Biology

Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man

(2014) Alexander Jais et al.   CELL

Iron ERRs with Salmonella

(2014) Ferric C. Fang et al.   Cell Host & Microbe

Distinct Roles of the Salmonella enterica Serovar Typhimurium CyaY and YggX Proteins in the Biosynthesis and Repair of Iron-Sulfur Clusters

(2014) Jyoti Velayudhan et al.   INFECTION AND IMMUNITY

Macrophages sense and kill bacteria through carbon monoxide–dependent inflammasome activation

(2014) Barbara Wegiel et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of mammalian siderophore 2,5-DHBA in the innate immune response to infection

(2014) Zhuoming Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development of a Multipurpose GATEWAY-Based Lentiviral Tetracycline-Regulated Conditional RNAi System (GLTR)

(2014) Reinhard Sigl et al.   PLoS One

Iron at the interface of immunity and infection

(2014) Manfred Nairz et al.   Frontiers in Pharmacology

Iron in Infection and Immunity

(2013) James E. Cassat et al.   Cell Host & Microbe

Heme Catabolism by Heme Oxygenase-1 Confers Host Resistance to Mycobacterium Infection

(2013) Sandro Silva-Gomes et al.   INFECTION AND IMMUNITY

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

(2013) Manfred Nairz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Iron and citrate export by a major facilitator superfamily pump regulates metabolism and stress resistance in Salmonella Typhimurium

(2013) E. R. Frawley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Mammalian Iron Homeostasis

(2012) Kostas Pantopoulos et al.   BIOCHEMISTRY

Ferroportin-mediated iron transport: Expression and regulation

(2012) Diane M. Ward et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Metabolic Adaptation to Tissue Iron Overload Confers Tolerance to Malaria

(2012) Raffaella Gozzelino et al.   Cell Host & Microbe

Carbon Monoxide and Heme Oxygenase-1 Prevent Intestinal Inflammation in Mice by Promoting Bacterial Clearance

(2012) Joseph C. Onyiah et al.   GASTROENTEROLOGY

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

Slc11a1 (Nramp1) impairs growth of Salmonella enterica serovar typhimurium in macrophages via stimulation of lipocalin-2 expression

(2012) Gernot Fritsche et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hepcidin and the Iron-Infection Axis

(2012) H. Drakesmith et al.   SCIENCE

Hepcidin regulation by innate immune and infectious stimuli

(2011) A. E. Armitage et al.   BLOOD

Iron sensing and signalling

(2011) Rayko Evstatiev et al.   GUT

Reactive Oxygen Species Mediate Bactericidal Killing Elicited by Carbon Monoxide-releasing Molecules

(2011) Ana Filipa N. Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Malaria impairs resistance to Salmonella through heme- and heme oxygenase–dependent dysfunctional granulocyte mobilization

(2011) Aubrey J Cunnington et al.   NATURE MEDICINE

Iron Homeostasis and the Inflammatory Response

(2010) Marianne Wessling-Resnick   Annual Review of Nutrition

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

The struggle for iron - a metal at the host-pathogen interface

(2010) Manfred Nairz et al.   CELLULAR MICROBIOLOGY

Divergent modulation of Chlamydia pneumoniae infection cycle in human monocytic and endothelial cells by iron, tryptophan availability and interferon gamma

(2010) Rosa Bellmann-Weiler et al.   IMMUNOBIOLOGY

Taming the Elephant: Salmonella Biology, Pathogenesis, and Prevention

(2010) H. L. Andrews-Polymenis et al.   INFECTION AND IMMUNITY

Visiting the cell biology of Salmonella infection

(2010) Amit Lahiri et al.   MICROBES AND INFECTION

Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex

(2010) Guanhu Bao et al.   Nature Chemical Biology

A Central Role for Free Heme in the Pathogenesis of Severe Sepsis

(2010) R. Larsen et al.   Science Translational Medicine

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2

(2009) M. Nairz et al.   BLOOD

Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications

(2009) I. Theurl et al.   BLOOD

Iron in innate immunity: starve the invaders

(2009) Tomas Ganz   CURRENT OPINION IN IMMUNOLOGY

Cytoprotective Function of Heme Oxygenase 1 Induced by a Nitrated Cyclic Nucleotide Formed during Murine Salmonellosis

(2009) M. H. Zaki et al.   JOURNAL OF IMMUNOLOGY

The Heme Oxygenase-1/Carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-1

(2009) X. M. Wang et al.   JOURNAL OF IMMUNOLOGY

Exploring the antimicrobial action of a carbon monoxide-releasing compound through whole-genome transcription profiling of Escherichia coli

(2009) L. S. Nobre et al.   MICROBIOLOGY-SGM

Macrophage-inflammatory protein-3α/CCL-20 is transcriptionally induced by the iron chelator desferrioxamine in human mononuclear phagocytes through nuclear factor (NF)-κB

(2009) Luigi Varesio et al.   MOLECULAR IMMUNOLOGY

Iron availability and infection

(2008) Eugene D. Weinberg   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Iron depletion limits intracellular bacterial growth in macrophages

(2008) P. N. Paradkar et al.   BLOOD

A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia

(2008) Mathieu Desmard et al.   FASEB JOURNAL

Heme oxygenase-1–derived carbon monoxide enhances the host defense response to microbial sepsis in mice

(2008) Su Wol Chung et al.   JOURNAL OF CLINICAL INVESTIGATION

The iron export protein ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome

(2008) Kristopher E. Van Zandt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Biosynthesis and IroC-dependent export of the siderophore salmochelin are essential for virulence of Salmonella enterica serovar Typhimurium

(2008) Marie-Laure V. Crouch et al.   MOLECULAR MICROBIOLOGY

Hepatocyte-Specific Deletion of Heme Oxygenase-1 Disrupts Redox Homeostasis in Basal and Oxidative Environments

(2008) Takashi Mamiya et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

The carbon monoxide-releasing molecule CORM-2 inhibits the inflammatory response induced by cytokines in Caco-2 cells

(2007) J Megías et al.   BRITISH JOURNAL OF PHARMACOLOGY