An integrative test strategy for cancer hazard identification

The presence of extra chromosomes leads to genomic instability

(2016) Verena Passerini et al.   Nature Communications

Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells

(2015) Julie K. Buick et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells

(2015) Heng-Hong Li et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Protection of the Gametes Embryo/Fetus From Prenatal Radiation Exposure

(2015) Robert L. Brent   HEALTH PHYSICS

Recommended protocols for the liver micronucleus test: Report of the IWGT working group

(2015) Yoshifumi Uno et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Micronucleus test in rodent tissues other than liver or erythrocytes: Report of the IWGT working group

(2015) Yoshifumi Uno et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Relationships between p53 status, apoptosis and induction of micronuclei in different human and mouse cell lines in vitro: Implications for improving existing assays

(2015) James Whitwell et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)

(2015) Günter Speit et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Approaches for identifying germ cell mutagens: Report of the 2013 IWGT workshop on germ cell assays☆

(2015) Carole L. Yauk et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding

(2015) Giel Hendriks et al.   TOXICOLOGICAL SCIENCES

Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the Health and Environmental Sciences Institute

(2015) Isabelle R. Miousse et al.   TOXICOLOGY

Gaining acceptance for the use of in vitro toxicity assays and QIVIVE in regulatory risk assessment

(2015) M.E. (Bette) Meek et al.   TOXICOLOGY

Quantitative in vitro-to-in vivo extrapolation in a high-throughput environment

(2015) Barbara A. Wetmore   TOXICOLOGY

Biotransformation in vitro: An essential consideration in the quantitative in vitro-to-in vivo extrapolation (QIVIVE) of toxicity data

(2015) Iwona Wilk-Zasadna et al.   TOXICOLOGY

In vivo murine hepatic microRNA and mRNA expression signatures predicting the (non-)genotoxic carcinogenic potential of chemicals

(2014) Joost P. M. Melis et al.   ARCHIVES OF TOXICOLOGY

Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment

(2014) G.E. Johnson et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Quantitative dose-response analysis of ethyl methanesulfonate genotoxicity in adultgpt-delta transgenic mice

(2014) Xuefei Cao et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence

(2014) M. E. Bette Meek et al.   JOURNAL OF APPLIED TOXICOLOGY

Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses

(2014) K. E. Chapman et al.   MUTAGENESIS

Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. III: Sensitivity of human cell types to known genotoxic agents

(2014) Paul Fowler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Effects of lowering the proposed top-concentration limit in an in vitro chromosomal aberration test on assay sensitivity and on the reduction of the number of false positives

(2014) Takeshi Morita et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? II. Construction and analysis of a consolidated database

(2014) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines

(2014) Hanna L Karlsson et al.   Particle and Fibre Toxicology

Cross-Platform Toxicogenomics for the Prediction of Non-Genotoxic Hepatocarcinogenesis in Rat

(2014) Michael Römer et al.   PLoS One

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)

(2014) Knut Erik Tollefsen et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Advancing the 3Rs in regulatory toxicology – Carcinogenicity testing: Scope for harmonisation and advancing the 3Rs in regulated sectors of the European Union

(2014) Erwin Annys et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans

(2014) Bas Blaauboer   ALTEX-Alternatives to Animal Experimentation

Nongenotoxic Carcinogenicity of Chemicals: Mechanisms of Action and Early Recognition through a New Set of Structural Alerts

(2013) Romualdo Benigni et al.   CHEMICAL REVIEWS

The use of genetically modified mice in cancer risk assessment: Challenges and limitations

(2013) David A. Eastmond et al.   CRITICAL REVIEWS IN TOXICOLOGY

Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment

(2013) Steven M. Bryce et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Evaluation of the utility of the lifetime mouse bioassay in the identification of cancer hazards for humans

(2013) Thomas G. Osimitz et al.   FOOD AND CHEMICAL TOXICOLOGY

New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis

(2013) M. E. Meek et al.   JOURNAL OF APPLIED TOXICOLOGY

The Utility of Modeling and Simulation in Drug Development and Regulatory Review

(2013) Shiew-Mei Huang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A Metabolomics Investigation of Non-genotoxic Carcinogenicity in the Rat

(2013) Zsuzsanna Ament et al.   JOURNAL OF PROTEOME RESEARCH

Comet assay in reconstructed 3D human epidermal skin models--investigation of intra- and inter-laboratory reproducibility with coded chemicals

(2013) A. A. Reus et al.   MUTAGENESIS

Epigenetic profiles as defined signatures of xenobiotic exposure

(2013) John P. Thomson et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment

(2013) Jos G. Bessems et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Use of Human In Vitro Skin Models for Accurate and Ethical Risk Assessment: Metabolic Considerations

(2013) Nicola J. Hewitt et al.   TOXICOLOGICAL SCIENCES

Relative Impact of Incorporating Pharmacokinetics on Predicting In Vivo Hazard and Mode of Action from High-Throughput In Vitro Toxicity Assays

(2013) Barbara A. Wetmore et al.   TOXICOLOGICAL SCIENCES

The Cosmetics Europe strategy for animal-free genotoxicity testing: Project status up-date

(2013) S. Pfuhler et al.   TOXICOLOGY IN VITRO

lazar: a modular predictive toxicology framework

(2013) Andreas Maunz et al.   Frontiers in Pharmacology

Oxidative DNA Damage and Nucleotide Excision Repair

(2012) Joost P.M. Melis et al.   ANTIOXIDANTS & REDOX SIGNALING

Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes

(2012) Mirjam M. Schaap et al.   ARCHIVES OF TOXICOLOGY

DNA methylome alterations in chemical carcinogenesis

(2012) Igor P. Pogribny et al.   CANCER LETTERS

Physiologically Based Pharmacokinetics Joined With In Vitro–In Vivo Extrapolation of ADME: A Marriage Under the Arch of Systems Pharmacology

(2012) A Rostami-Hodjegan   CLINICAL PHARMACOLOGY & THERAPEUTICS

Quantitativein vitrotoin vivoextrapolation of cell-based toxicity assay results

(2012) Miyoung Yoon et al.   CRITICAL REVIEWS IN TOXICOLOGY

Quantitative approaches for assessing dose-response relationships in genetic toxicology studies

(2012) B.B. Gollapudi et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

International round-robin study on the Ames fluctuation test

(2012) G. Reifferscheid et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Effective use of the Pig-a gene mutation assay for mutagenicity screening: measuring CD59-deficient red blood cells in rats treated with genotoxic chemicals

(2012) Takafumi Kimoto et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Automatic analysis of the micronucleus test in primary human lymphocytes using image analysis

(2012) W. Frieauff et al.   MUTAGENESIS

Recommendations for safety testing with the in vivo comet assay

(2012) Marie Z. Vasquez   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Direct comparison of the Ames microplate format (MPF) test in liquid medium with the standard Ames pre-incubation assay on agar plates by use of equivocal to weakly positive test compounds

(2012) Sini Flückiger-Isler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Discrimination of genotoxic and non-genotoxic hepatocarcinogens by statistical analysis based on gene expression profiling in the mouse liver as determined by quantitative real-time PCR

(2012) Takashi Watanabe et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. II. Importance of accurate toxicity measurement

(2012) Paul Fowler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Evaluation of chemicals requiring metabolic activation in the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay

(2012) Marilyn J. Aardema et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Can the Ames test provide an insight into nano-object mutagenicity? Investigating the interaction between nano-objects and bacteria

(2012) Martin J. D. Clift et al.   Nanotoxicology

Efficient Monitoring of In Vivo Pig-a Gene Mutation and Chromosomal Damage: Summary of 7 Published Studies and Results From 11 New Reference Compounds

(2012) Stephen D. Dertinger et al.   TOXICOLOGICAL SCIENCES

Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches

(2012) Sandra Coecke et al.   TOXICOLOGY IN VITRO

History of Chronic Toxicity and Animal Carcinogenicity Studies for Pharmaceuticals

(2012) A. C. Jacobs et al.   VETERINARY PATHOLOGY

Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

(2011) Sarah Adler et al.   ARCHIVES OF TOXICOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Using mode of action information to improve regulatory decision-making: An ECETOC/ILSI RF/HESI workshop overview

(2011) Neil Carmichael et al.   CRITICAL REVIEWS IN TOXICOLOGY

Historical perspective on the use of animal bioassays to predict carcinogenicity: Evolution in design and recognition of utility

(2011) L. A. Beyer et al.   CRITICAL REVIEWS IN TOXICOLOGY

Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment

(2011) Giel Hendriks et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenetics assays (chromosome aberrations and micronucleus)

(2011) Sheila Galloway et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

OECD Detailed Review Paper (DRP) number 31 on “Cell Transformation Assays for Detection of Chemical Carcinogens”: main results and conclusions

(2011) Paule Vasseur et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines

(2011) S.H. Doak et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. I. Choice of cell type

(2011) Paul Fowler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Evaluation of carcinogenicity studies of medicinal products for human use authorised via the European centralised procedure (1995–2009)

(2011) Anita Friedrich et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Why and how to combine evidence in environmental assessments: Weighing evidence and building cases

(2011) Glenn W. Suter et al.   SCIENCE OF THE TOTAL ENVIRONMENT

An Analysis of Pharmaceutical Experience with Decades of Rat Carcinogenicity Testing

(2011) Frank D. Sistare et al.   TOXICOLOGIC PATHOLOGY

Transgenic Animal Models in Toxicology: Historical Perspectives and Future Outlook

(2011) Darrell R. Boverhof et al.   TOXICOLOGICAL SCIENCES

The ToxTracker Assay: Novel GFP Reporter Systems that Provide Mechanistic Insight into the Genotoxic Properties of Chemicals

(2011) Giel Hendriks et al.   TOXICOLOGICAL SCIENCES

Development and Evaluation of a Genomic Signature for the Prediction and Mechanistic Assessment of Nongenotoxic Hepatocarcinogens in the Rat

(2011) Mark R. Fielden et al.   TOXICOLOGICAL SCIENCES

Prediction model of potential hepatocarcinogenicity of rat hepatocarcinogens using a large-scale toxicogenomics database

(2011) Takeki Uehara et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oxidative stress and oxidative damage in chemical carcinogenesis

(2011) James E. Klaunig et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of the genotoxic compounds, benzo[a]pyrene and cyclophosphamide on phase 1 and 2 activities in EpiDerm™ models

(2011) Christine Götz et al.   XENOBIOTICA

MEGen: a physiologically based pharmacokinetic model generator

(2011) George Loizou   Frontiers in Pharmacology

New public QSAR model for carcinogenicity

(2010) Natalja Fjodorova et al.   Chemistry Central Journal

Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review

(2010) P Zhao et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genotoxicity testing: Moving beyond qualitative “screen and bin” approach towards characterization of dose-response and thresholds

(2010) Lynn H. Pottenger et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The in vivo pig-a gene mutation assay, a potential tool for regulatory safety assessment

(2010) Vasily N. Dobrovolsky et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

GADD45α induction in the greenscreen HC indicator assay does not occur independently of cytotoxicity

(2010) Andrew J. Olaharski et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Further analysis of Ames-negative rodent carcinogens that are only genotoxic in mammalian cells in vitro at concentrations exceeding 1 mM, including retesting of compounds of concern

(2010) D. Kirkland et al.   MUTAGENESIS

Analysis of published data for top concentration considerations in mammalian cell genotoxicity testing

(2010) James M. Parry et al.   MUTAGENESIS

Adaptations of the in vitro MN assay for the genotoxicity assessment of nanomaterials

(2010) L. Gonzalez et al.   MUTAGENESIS

Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure

(2010) A. Rossnerova et al.   MUTAGENESIS

In vitro genotoxicity testing using the micronucleus assay in cell lines, human lymphocytes and 3D human skin models

(2010) M. Kirsch-Volders et al.   MUTAGENESIS

Automated image analysis of micronuclei by IMSTAR for biomonitoring

(2010) I. Decordier et al.   MUTAGENESIS

A pre-validation transferability study of the GreenScreen HC GADD45a-GFP assay with a metabolic activation system (S9)

(2010) Nicholas Billinton et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Characterizing and predicting carcinogenicity and mode of action using conventional and toxicogenomics methods

(2010) Michael D. Waters et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Evaluation of Possible Carcinogenic Risk to Humans Based on Liver Tumors in Rodent Assays

(2010) Samuel M. Cohen   TOXICOLOGIC PATHOLOGY

Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening

(2010) Daniel M. Rotroff et al.   TOXICOLOGICAL SCIENCES

Xenobiotic metabolism gene expression in the EpiDerm™ in vitro 3D human epidermis model compared to human skin

(2010) T. Hu et al.   TOXICOLOGY IN VITRO

An Evaluation of Chronic 6- and 12-Month Rat Toxicology Studies as Predictors of 2-Year Tumor Outcome

(2010) M. V. Reddy et al.   VETERINARY PATHOLOGY

Modelling and PBPK Simulation in Drug Discovery

(2009) Hannah M. Jones et al.   AAPS Journal

Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models

(2009) Martijs J. Jonker et al.   CARCINOGENESIS

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

(2009) F. Colotta et al.   CARCINOGENESIS

Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways

(2009) A. J. Schetter et al.   CARCINOGENESIS

Application of Key Events Analysis to Chemical Carcinogens and Noncarcinogens

(2009) Alan R. Boobis et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The mouse carcinogenicity study is no longer a scientifically justifiable core data requirement for the safety assessment of pesticides

(2009) Richard Billington et al.   CRITICAL REVIEWS IN TOXICOLOGY

Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme

(2009) D. A. Eastmond et al.   MUTAGENESIS

Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP ‘GreenScreen HC’ genotoxicity assay

(2009) Paul W. Hastwell et al.   MUTAGENESIS

Further development of the EpiDerm™ 3D reconstructed human skin micronucleus (RSMN) assay

(2009) Greg C. Mun et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities—Report from an ECVAM workshop

(2009) Stefan Pfuhler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

GADD45a-GFP GreenScreen HC assay results for the ECVAM recommended lists of genotoxic and non-genotoxic chemicals for assessment of new genotoxicity tests

(2009) Louise Birrell et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

(2009) Lya G. Hernández et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments

(2009) Shengde Wu et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A Data-Based Assessment of Alternative Strategies for Identification of Potential Human Cancer Hazards

(2009) Alan R. Boobis et al.   TOXICOLOGIC PATHOLOGY

Characterization and Interlaboratory Comparison of a Gene Expression Signature for Differentiating Genotoxic Mechanisms

(2009) Heidrun Ellinger-Ziegelbauer et al.   TOXICOLOGICAL SCIENCES

Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH)

(2008) W. Lilienblum et al.   ARCHIVES OF TOXICOLOGY

Windows based general PBPK/PD modeling software

(2008) Richard H. Luecke et al.   COMPUTERS IN BIOLOGY AND MEDICINE

IPCS Framework for Analyzing the Relevance of a Noncancer Mode of Action for Humans

(2008) Alan R. Boobis et al.   CRITICAL REVIEWS IN TOXICOLOGY

Development of an in vivo gene mutation assay using the endogenousPig-Agene: II. Selection ofPig-Amutant rat spleen T-cells with proaerolysin and sequencingPig-AcDNA from the mutants

(2008) Daishiro Miura et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method

(2008) Nicholas Billinton et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop

(2008) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Oxidative stress in environmental-induced carcinogenesis

(2008) Salvador Mena et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Improving prediction of chemical carcinogenicity by considering multiple mechanisms and applying toxicogenomic approaches

(2008) Kathryn Z. Guyton et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

An evaluation of the implementation of the Cramer classification scheme in the Toxtree software

(2008) G. Patlewicz et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Quantitative Interpretation of Human Biomonitoring Data

(2008) Harvey J. Clewell et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies

(2007) Heidrun Ellinger-Ziegelbauer et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS