Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes

Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis—Persistent pollutants affect programmed cell death

(2011) Martin Chopra et al.   CRITICAL REVIEWS IN TOXICOLOGY

Phenobarbital Mediates an Epigenetic Switch at the Constitutive Androstane Receptor (CAR) Target Gene Cyp2b10 in the Liver of B6C3F1 Mice

(2011) Harri Lempiäinen et al.   PLoS One

Development and Evaluation of a Genomic Signature for the Prediction and Mechanistic Assessment of Nongenotoxic Hepatocarcinogens in the Rat

(2011) Mark R. Fielden et al.   TOXICOLOGICAL SCIENCES

Deregulation of Cancer-Related Pathways in Primary Hepatocytes Derived from DNA Repair-Deficient Xpa−/−p53+/− Mice upon Exposure to Benzo[a]pyrene

(2011) Petra C. E. van Kesteren et al.   TOXICOLOGICAL SCIENCES

Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis

(2010) Sayeepriyadarshini Anakk et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene expression profiling in primary mouse hepatocytes discriminates true from false-positive genotoxic compounds

(2010) K. Mathijs et al.   MUTAGENESIS

Characterizing and predicting carcinogenicity and mode of action using conventional and toxicogenomics methods

(2010) Michael D. Waters et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Differential Gene Regulation by the Human and Mouse Aryl Hydrocarbon Receptor

(2010) Colin A. Flaveny et al.   TOXICOLOGICAL SCIENCES

Assessing the Metabolic Competence of Sandwich-Cultured Mouse Primary Hepatocytes

(2009) K. Mathijs et al.   DRUG METABOLISM AND DISPOSITION

New molecular insights into the mechanisms of cholestasis

(2009) Martin Wagner et al.   JOURNAL OF HEPATOLOGY

Overexpression of sterol carrier protein-2 differentially alters hepatic cholesterol accumulation in cholesterol-fed mice

(2009) Barbara P. Atshaves et al.   JOURNAL OF LIPID RESEARCH

Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy

(2009) Mitsuhiro Hirode et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

(2009) Lya G. Hernández et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Use of Short-term Transcriptional Profiles to Assess the Long-term Cancer-Related Safety of Environmental and Industrial Chemicals

(2009) Russell S. Thomas et al.   TOXICOLOGICAL SCIENCES

Aroclor 1254 induced cytotoxicity and mitochondrial dysfunction in isolated rat hepatocytes

(2009) Hamdy A.A. Aly et al.   TOXICOLOGY

Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH)

(2008) W. Lilienblum et al.   ARCHIVES OF TOXICOLOGY

Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms

(2008) Detmar Beyersmann et al.   ARCHIVES OF TOXICOLOGY

A Preliminary Operational Classification System for Nonmutagenic Modes of Action for Carcinogenesis

(2008) D. Hattis et al.   CRITICAL REVIEWS IN TOXICOLOGY

Human health risk assessment for peroxisome proliferators: More than 30 years of research

(2008) Marco Fidaleo   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Low-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the aryl hydrocarbon receptor-mediated pathway in mouse liver

(2008) Shoko Sato et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY