The Wnt–β-Catenin–IL-10 Signaling Axis in Intestinal APCs Protects Mice from Colitis-Associated Colon Cancer in Response to Gut Microbiota

The Intestinal Microbiota in Colorectal Cancer

(2018) Herbert Tilg et al.   CANCER CELL

Canonical Wnt Signaling in CD11c+APCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon

(2018) Daniel Swafford et al.   JOURNAL OF IMMUNOLOGY

GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis

(2018) Punithavathi Ranganathan et al.   JOURNAL OF IMMUNOLOGY

Microbial markers in colorectal cancer detection and/or prognosis

(2018) Romain Villéger et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Preliminary Comparison of Oral and Intestinal Human Microbiota in Patients with Colorectal Cancer: A Pilot Study

(2018) Edda Russo et al.   Frontiers in Microbiology

Protein kinase p38α signaling in dendritic cells regulates colon inflammation and tumorigenesis

(2018) Tingting Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis

(2017) Jeonghyun Ahn et al.   Cell Reports

TH17 Cell and Epithelial Cell Crosstalk during Inflammatory Bowel Disease and Carcinogenesis

(2017) Jan Kempski et al.   Frontiers in Immunology

Homeostatic PPARα Signaling Limits Inflammatory Responses to Commensal Microbiota in the Intestine

(2016) Indumathi Manoharan et al.   JOURNAL OF IMMUNOLOGY

The microbiota in adaptive immune homeostasis and disease

(2016) Kenya Honda et al.   NATURE

Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury

(2016) Subhrajit Saha et al.   Nature Communications

Modulation of Inflammatory Responses by Wnt/β-Catenin Signaling in Dendritic Cells: A Novel Immunotherapy Target for Autoimmunity and Cancer

(2016) Amol Suryawanshi et al.   Frontiers in Immunology

 -Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells

(2015) Y. Hong et al.   CANCER RESEARCH

Cytokines, IBD, and Colitis-associated Cancer

(2015) Ralph Francescone et al.   INFLAMMATORY BOWEL DISEASES

Phenotypic and functional profiling of mouse intestinal antigen presenting cells

(2015) Akihito Harusato et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Canonical Wnt Signaling in Dendritic Cells Regulates Th1/Th17 Responses and Suppresses Autoimmune Neuroinflammation

(2015) Amol Suryawanshi et al.   JOURNAL OF IMMUNOLOGY

The activation of Wnt signaling by a STAT6-dependent macrophage phenotype promotes mucosal repair in murine IBD

(2015) J Cosín-Roger et al.   Mucosal Immunology

Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity

(2015) Yuan Hong et al.   OncoImmunology

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer

(2015) Annalucia Serafino et al.   Oncotarget

Dual Function of p38α MAPK in Colon Cancer: Suppression of Colitis-Associated Tumor Initiation but Requirement for Cancer Cell Survival

(2014) Jalaj Gupta et al.   CANCER CELL

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Regulation of the Immune System by the Resident Intestinal Bacteria

(2014) Nobuhiko Kamada et al.   GASTROENTEROLOGY

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Colorectal cancer in inflammatory bowel disease: The risk, pathogenesis, prevention and diagnosis

(2014) Eun Ran Kim   WORLD JOURNAL OF GASTROENTEROLOGY

Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer

(2014) Janelle C. Arthur et al.   Nature Communications

SOCS3, a Major Regulator of Infection and Inflammation

(2014) Berit Carow et al.   Frontiers in Immunology

Role of TH17 cytokines in the control of colorectal cancer

(2014) Veronica De Simone et al.   OncoImmunology

Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora

(2013) Ju Qiu et al.   IMMUNITY

Dysbiosis Signature of Fecal Microbiota in Colorectal Cancer Patients

(2013) Na Wu et al.   MICROBIAL ECOLOGY

The Gut Microbiome Modulates Colon Tumorigenesis

(2013) J. P. Zackular et al.   mBio

The Microbiome in Infectious Disease and Inflammation

(2012) Kenya Honda et al.   Annual Review of Immunology

Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APC Min/+ mice

(2012) Yinghui Li et al.   CARCINOGENESIS

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

SOCS3 in immune regulation of inflammatory bowel disease and inflammatory bowel disease-related cancer

(2012) Yi Li et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

(2012) Sergei I. Grivennikov et al.   NATURE

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

(2012) J. C. Arthur et al.   SCIENCE

Colorectal cancer in inflammatory bowel disease: What is the real magnitude of the risk?

(2012) Jessica K Dyson   WORLD JOURNAL OF GASTROENTEROLOGY

Interleukin-10 Ablation Promotes Tumor Development, Growth, and Metastasis

(2011) T. Tanikawa et al.   CANCER RESEARCH

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Dendritic cells in oral tolerance in the gut

(2011) Maria Rescigno   CELLULAR MICROBIOLOGY

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

(2011) M. Joossens et al.   GUT

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

(2011) Samuel Huber et al.   IMMUNITY

Dendritic cell control of tolerogenic responses

(2011) Santhakumar Manicassamy et al.   IMMUNOLOGICAL REVIEWS

The role of p38 mitogen-activated protein kinase in the pathogenesis of inflammatory bowel disease

(2011) Ya Jing FENG et al.   Journal of Digestive Diseases

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Homeostasis and Inflammation in the Intestine

(2010) Wendy S. Garrett et al.   CELL

Distinct Effects of p38α Deletion in Myeloid Lineage and Gut Epithelia in Mouse Models of Inflammatory Bowel Disease

(2010) Motoyuki Otsuka et al.   GASTROENTEROLOGY

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

Expression profiling of Wnt family of genes in normal and inflammatory bowel disease primary human intestinal myofibroblasts and normal human colonic crypt epithelial cells

(2010) K. R. Hughes et al.   INFLAMMATORY BOWEL DISEASES

Programming dendritic cells to induce TH2 and tolerogenic responses

(2010) Bali Pulendran et al.   NATURE IMMUNOLOGY

Activation of  -Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine

(2010) S. Manicassamy et al.   SCIENCE

Regulatory Lymphocytes and Intestinal Inflammation

(2009) Ana Izcue et al.   Annual Review of Immunology

Proinflammatory cytokines and IL-10 in inflammatory bowel disease and colorectal cancer patients

(2009) Andrzej Szkaradkiewicz et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Colitis-Associated Colorectal Cancer Driven by T-bet Deficiency in Dendritic Cells

(2009) Wendy S. Garrett et al.   CANCER CELL

Toll-like receptor 2–dependent induction of vitamin A–metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity

(2009) Santhakumar Manicassamy et al.   NATURE MEDICINE

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modulation of the Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility

(2009) Joshua M. Uronis et al.   PLoS One

Genome-wide association studies - A summary for theclinical gastroenterologist

(2009) Espen Melum et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

(2008) Andre Franke et al.   NATURE GENETICS