Canonical Wnt Signaling in CD11c+APCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon

Homeostatic Immunity and the Microbiota

(2017) Yasmine Belkaid et al.   IMMUNITY

Retinoic Acid Regulates Immune Responses by Promoting IL-22 and Modulating S100 Proteins in Viral Hepatitis

(2017) Zuliang Jie et al.   JOURNAL OF IMMUNOLOGY

Endothelial Wnt/β-catenin signaling reduces immune cell infiltration in multiple sclerosis

(2017) Justin E. Lengfeld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Homeostatic PPARα Signaling Limits Inflammatory Responses to Commensal Microbiota in the Intestine

(2016) Indumathi Manoharan et al.   JOURNAL OF IMMUNOLOGY

Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses

(2016) Wujing Dai et al.   MEDIATORS OF INFLAMMATION

Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury

(2016) Subhrajit Saha et al.   Nature Communications

Moringin activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis

(2016) Sabrina Giacoppo et al.   Drug Design Development and Therapy

Modulation of Inflammatory Responses by Wnt/β-Catenin Signaling in Dendritic Cells: A Novel Immunotherapy Target for Autoimmunity and Cancer

(2016) Amol Suryawanshi et al.   Frontiers in Immunology

 -Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells

(2015) Y. Hong et al.   CANCER RESEARCH

Phenotypic and functional profiling of mouse intestinal antigen presenting cells

(2015) Akihito Harusato et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Canonical Wnt Signaling in Dendritic Cells Regulates Th1/Th17 Responses and Suppresses Autoimmune Neuroinflammation

(2015) Amol Suryawanshi et al.   JOURNAL OF IMMUNOLOGY

The activation of Wnt signaling by a STAT6-dependent macrophage phenotype promotes mucosal repair in murine IBD

(2015) J Cosín-Roger et al.   Mucosal Immunology

IL-22BP is produced by eosinophils in human gut and blocks IL-22 protective actions during colitis

(2015) J C Martin et al.   Mucosal Immunology

Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy

(2015) A. Holtzhausen et al.   Cancer Immunology Research

Tumors induce immune tolerance through activation of β-catenin/TCF4 signaling in dendritic cells: A novel therapeutic target for cancer immunotherapy

(2015) Amol Suryawanshi et al.   OncoImmunology

Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity

(2015) Yuan Hong et al.   OncoImmunology

Interleukin-10 Enhances the Intestinal Epithelial Barrier in the Presence of Corticosteroids through p38 MAPK Activity in Caco-2 Monolayers: A Possible Mechanism for Steroid Responsiveness in Ulcerative Colitis

(2015) Violeta Lorén et al.   PLoS One

Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis

(2015) C. Henrique Alves et al.   PLoS One

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

TLR2-Dependent Activation of β-Catenin Pathway in Dendritic Cells Induces Regulatory Responses and Attenuates Autoimmune Inflammation

(2014) Indumathi Manoharan et al.   JOURNAL OF IMMUNOLOGY

Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis

(2014) A. Mortha et al.   SCIENCE

Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora

(2013) Ju Qiu et al.   IMMUNITY

Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation

(2013) Lisa A. Mielke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-22 Deficiency Alters Colonic Microbiota To Be Transmissible and Colitogenic

(2013) L. A. Zenewicz et al.   JOURNAL OF IMMUNOLOGY

Canonical and Noncanonical Wnt Proteins Program Dendritic Cell Responses for Tolerance

(2013) C. Oderup et al.   JOURNAL OF IMMUNOLOGY

IL-23R+ innate lymphoid cells induce colitis via interleukin-22-dependent mechanism

(2013) A Eken et al.   Mucosal Immunology

M2 Macrophages Activate WNT Signaling Pathway in Epithelial Cells: Relevance in Ulcerative Colitis

(2013) Jesús Cosín-Roger et al.   PLoS One

The Microbiome in Infectious Disease and Inflammation

(2012) Kenya Honda et al.   Annual Review of Immunology

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Intestinal Commensal Microbes as Immune Modulators

(2012) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Dietary and commensal derived nutrients: shaping mucosal and systemic immunity

(2012) Sean P Spencer et al.   CURRENT OPINION IN IMMUNOLOGY

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

(2012) Michael H. Shaw et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Dendritic cells in oral tolerance in the gut

(2011) Maria Rescigno   CELLULAR MICROBIOLOGY

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

(2011) M. Joossens et al.   GUT

The Role of Retinoic Acid in Tolerance and Immunity

(2011) Jason A. Hall et al.   IMMUNITY

Lrp5 and Lrp6 play compensatory roles in mouse intestinal development

(2011) Zhendong Zhong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Wnt5a Skews Dendritic Cell Differentiation to an Unconventional Phenotype with Tolerogenic Features

(2011) Jaris Valencia et al.   JOURNAL OF IMMUNOLOGY

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Homeostasis and Inflammation in the Intestine

(2010) Wendy S. Garrett et al.   CELL

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the Gut

(2010) Gregory F. Sonnenberg et al.   IMMUNITY

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling

(2010) Hergen Spits et al.   NATURE IMMUNOLOGY

Programming dendritic cells to induce TH2 and tolerogenic responses

(2010) Bali Pulendran et al.   NATURE IMMUNOLOGY

Activation of  -Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine

(2010) S. Manicassamy et al.   SCIENCE

Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease

(2008) Lauren A. Zenewicz et al.   IMMUNITY

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

(2008) Ken Sugimoto et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-22 in mucosal immunity

(2008) W Ouyang et al.   Mucosal Immunology

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE