Homeostatic PPARα Signaling Limits Inflammatory Responses to Commensal Microbiota in the Intestine

Intestinal Antigen-Presenting Cells

(2015) Kyle L. Flannigan et al.   AMERICAN JOURNAL OF PATHOLOGY

Phenotypic and functional profiling of mouse intestinal antigen presenting cells

(2015) Akihito Harusato et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Canonical Wnt Signaling in Dendritic Cells Regulates Th1/Th17 Responses and Suppresses Autoimmune Neuroinflammation

(2015) Amol Suryawanshi et al.   JOURNAL OF IMMUNOLOGY

PPARα-dependent exacerbation of experimental colitis by the hypolipidemic drug fenofibrate

(2014) Yunpeng Qi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Chemokine Receptor CXCR6 Controls the Functional Topography of Interleukin-22 Producing Intestinal Innate Lymphoid Cells

(2014) Naoko Satoh-Takayama et al.   IMMUNITY

Segmented Filamentous Bacteria Antigens Presented by Intestinal Dendritic Cells Drive Mucosal Th17 Cell Differentiation

(2014) Yoshiyuki Goto et al.   IMMUNITY

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

CX3CR1+mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22

(2014) Randy S. Longman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review

(2014) Bogna Grygiel-Górniak   Nutrition Journal

PPAR-Gamma in Ulcerative Colitis: A Novel Target for Intervention

(2013) Benjamin Bertin et al.   CURRENT DRUG TARGETS

Palmitoylethanolamide improves colon inflammation through an enteric glia/toll like receptor 4-dependent PPAR-α activation

(2013) Giuseppe Esposito et al.   GUT

Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora

(2013) Ju Qiu et al.   IMMUNITY

IL-22 Deficiency Alters Colonic Microbiota To Be Transmissible and Colitogenic

(2013) L. A. Zenewicz et al.   JOURNAL OF IMMUNOLOGY

Nutritional protective mechanisms against gut inflammation

(2013) Monica Viladomiu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

IL-23R+ innate lymphoid cells induce colitis via interleukin-22-dependent mechanism

(2013) A Eken et al.   Mucosal Immunology

The Microbiome in Infectious Disease and Inflammation

(2012) Kenya Honda et al.   Annual Review of Immunology

Dietary and commensal derived nutrients: shaping mucosal and systemic immunity

(2012) Sean P Spencer et al.   CURRENT OPINION IN IMMUNOLOGY

The Peroxisome Proliferator-activated Receptor γ (PPARγ) Controls Natural Protective Mechanisms against Lipid Peroxidation in Amyotrophic Lateral Sclerosis

(2012) Valeria Benedusi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

(2012) Michael H. Shaw et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CX3CR1+ macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium

(2012) C Manta et al.   Mucosal Immunology

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

(2011) Ju Qiu et al.   IMMUNITY

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

Dietary conjugated linoleic acid and n-3 polyunsaturated fatty acids in inflammatory bowel disease

(2010) Josep Bassaganya-Riera et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the Gut

(2010) Gregory F. Sonnenberg et al.   IMMUNITY

PPARα contributes to colonic protection in mice with DSS-induced colitis

(2010) Yasu-Taka Azuma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling

(2010) Hergen Spits et al.   NATURE IMMUNOLOGY

Programming dendritic cells to induce TH2 and tolerogenic responses

(2010) Bali Pulendran et al.   NATURE IMMUNOLOGY

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of  -Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine

(2010) S. Manicassamy et al.   SCIENCE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

PPAR  blocks glucocorticoid receptor  -mediated transactivation but cooperates with the activated glucocorticoid receptor   for transrepression on NF- B

(2009) N. Bougarne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-α MODULATES THE ANTI-INFLAMMATORY EFFECT OF GLUCOCORTICOIDS IN A MODEL OF INFLAMMATORY BOWEL DISEASE IN MICE

(2009) Luisa Riccardi et al.   SHOCK

PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression

(2008) Heleen M de Vogel-van den Bosch et al.   BMC GENOMICS

Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease

(2008) Lauren A. Zenewicz et al.   IMMUNITY

IL-22 in mucosal immunity

(2008) W Ouyang et al.   Mucosal Immunology

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

(2008) Marina Cella et al.   NATURE

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE