A genetic memory initiates the epigenetic loop necessary to preserve centromere position

From evolution to function: Two sides of the same CENP-B coin?

(2020) Riccardo Gamba et al.   EXPERIMENTAL CELL RESEARCH

CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly

(2020) Koichiro Otake et al.   JOURNAL OF CELL SCIENCE

Phosphorylation of CENP-A on serine 7 does not control centromere function

(2019) Viviana Barra et al.   Nature Communications

Human Artificial Chromosomes that Bypass Centromeric DNA

(2019) Glennis A. Logsdon et al.   CELL

De novo formation and epigenetic maintenance of centromere chromatin

(2019) Junichirou Ohzeki et al.   CURRENT OPINION IN CELL BIOLOGY

DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres

(2019) Yael Nechemia-Arbely et al.   NATURE CELL BIOLOGY

Keeping the Centromere under Control: A Promising Role for DNA Methylation

(2019) Scelfo et al.   Cells

Quiescent Cells Actively Replenish CENP-A Nucleosomes to Maintain Centromere Identity and Proliferative Potential

(2019) S. Zachary Swartz et al.   DEVELOPMENTAL CELL

Human chromosome‐specific aneuploidy is influenced by DNA ‐dependent centromeric features

(2019) Marie Dumont et al.   EMBO JOURNAL

Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing

(2019) Dongqing Pan et al.   Nature Communications

Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation

(2018) Georg O.M. Bobkov et al.   JOURNAL OF CELL BIOLOGY

Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80

(2018) Marion E. Pesenti et al.   MOLECULAR CELL

An intrinsic S/G2 checkpoint enforced by ATR

(2018) Joshua C. Saldivar et al.   SCIENCE

Centromere DNA Destabilizes H3 Nucleosomes to Promote CENP-A Deposition during the Cell Cycle

(2018) Manu Shukla et al.   CURRENT BIOLOGY

High-resolution mapping of centromeric protein association using APEX-chromatin fibers

(2018) Eftychia Kyriacou et al.   Epigenetics & Chromatin

The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA

(2018) V. Barra et al.   Nature Communications

Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres

(2017) Hua Xiao et al.   GENES & DEVELOPMENT

Rapid molecular assays to study human centromere genomics

(2017) Rafael Contreras-Galindo et al.   GENOME RESEARCH

Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

(2017) Valerie A. Schneider et al.   GENOME RESEARCH

Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points

(2017) Yael Nechemia-Arbely et al.   JOURNAL OF CELL BIOLOGY

A Dual Inhibitory Mechanism Sufficient to Maintain Cell-Cycle-Restricted CENP-A Assembly

(2017) Ana Stankovic et al.   MOLECULAR CELL

CENP-B protects centromere chromatin integrity by facilitating histone deposition via the H3.3-specific chaperone Daxx

(2017) Viacheslav M. Morozov et al.   Epigenetics & Chromatin

CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading

(2017) Dongqing Pan et al.   eLife

An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites

(2017) Peter J Skene et al.   eLife

KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation

(2016) Jun-ichirou Ohzeki et al.   DEVELOPMENTAL CELL

Licensing of Centromeric Chromatin Assembly through the Mis18α-Mis18β Heterotetramer

(2016) Isaac K. Nardi et al.   MOLECULAR CELL

Insights from biochemical reconstitution into the architecture of human kinetochores

(2016) John R. Weir et al.   NATURE

Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining

(2016) Peter Ly et al.   NATURE CELL BIOLOGY

Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression

(2016) Antoine Aze et al.   NATURE CELL BIOLOGY

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

Inheritance of the CENP-A chromatin domain is spatially and temporally constrained at human centromeres

(2016) Justyne E. Ross et al.   Epigenetics & Chromatin

Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres

(2016) Wei-Hao Shang et al.   Nature Communications

CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly

(2016) Sebastian Hoffmann et al.   Cell Reports

Differential Binding Partners of the Mis18α/β YIPPEE Domains Regulate Mis18 Complex Recruitment to Centromeres

(2016) Madison E. Stellfox et al.   Cell Reports

CENP-A Ubiquitylation Is Inherited through Dimerization between Cell Divisions

(2016) Yohei Niikura et al.   Cell Reports

CENP-A K124 Ubiquitylation Is Required for CENP-A Deposition at the Centromere

(2015) Yohei Niikura et al.   DEVELOPMENTAL CELL

Establishment of Centromeric Chromatin by the CENP-A Assembly Factor CAL1 Requires FACT-Mediated Transcription

(2015) Chin-Chi Chen et al.   DEVELOPMENTAL CELL

DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere Function

(2015) Daniele Fachinetti et al.   DEVELOPMENTAL CELL

CENP-C is a blueprint for constitutive centromere–associated network assembly within human kinetochores

(2015) Kerstin Klare et al.   JOURNAL OF CELL BIOLOGY

CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly

(2015) N. Shono et al.   JOURNAL OF CELL SCIENCE

ProLuCID: An improved SEQUEST-like algorithm with enhanced sensitivity and specificity

(2015) T. Xu et al.   Journal of Proteomics

Identification of the Post-translational Modifications Present in Centromeric Chromatin

(2015) Aaron O. Bailey et al.   MOLECULAR & CELLULAR PROTEOMICS

The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface

(2015) Kara L. McKinley et al.   MOLECULAR CELL

The molecular basis for centromere identity and function

(2015) Kara L. McKinley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stable complex formation of CENP-B with the CENP-A nucleosome

(2015) Risa Fujita et al.   NUCLEIC ACIDS RESEARCH

CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere

(2015) S. J. Falk et al.   SCIENCE

Depth-of-Focus Correction in Single-Molecule Data Allows Analysis of 3D Diffusion of the Glucocorticoid Receptor in the Nucleus

(2015) Rolf Harkes et al.   PLoS One

Polo-like Kinase 1 Licenses CENP-A Deposition at Centromeres

(2014) Kara L. McKinley et al.   CELL

The Centromere: Chromatin Foundation for the Kinetochore Machinery

(2014) Tatsuo Fukagawa et al.   DEVELOPMENTAL CELL

Centromere reference models for human chromosomes X and Y satellite arrays

(2014) K. H. Miga et al.   GENOME RESEARCH

A novel Alu-based real-time PCR method for the quantitative detection of plasma circulating cell-free DNA: Sensitivity and specificity for the diagnosis of myocardial infarction

(2014) XIAOLI LOU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Mitotic Regulator Mis18β Interacts with and Specifies the Centromeric Assembly of Molecular Chaperone Holliday Junction Recognition Protein (HJURP)

(2014) Jianyu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mislocalization of the Centromeric Histone Variant CenH3/CENP-A in Human Cells Depends on the Chaperone DAXX

(2014) Nicolas Lacoste et al.   MOLECULAR CELL

Phosphorylation and DNA Binding of HJURP Determine Its Centromeric Recruitment and Function in CenH3CENP-A Loading

(2014) Sebastian Müller et al.   Cell Reports

The quantitative architecture of centromeric chromatin

(2014) Dani L Bodor et al.   eLife

A long non-coding RNA is required for targeting centromeric protein A to the human centromere

(2014) Delphine Quénet et al.   eLife

Chromosome Engineering Allows the Efficient Isolation of Vertebrate Neocentromeres

(2013) Wei-Hao Shang et al.   DEVELOPMENTAL CELL

The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly

(2013) Tetsuya Hori et al.   JOURNAL OF CELL BIOLOGY

A two-step mechanism for epigenetic specification of centromere identity and function

(2013) Daniele Fachinetti et al.   NATURE CELL BIOLOGY

Nap1 regulates proper CENP-B binding to nucleosomes

(2013) Hiroaki Tachiwana et al.   NUCLEIC ACIDS RESEARCH

A Conserved Mechanism for Centromeric Nucleosome Recognition by Centromere Protein CENP-C

(2013) H. Kato et al.   SCIENCE

HJURP Uses Distinct CENP-A Surfaces to Recognize and to Stabilize CENP-A/Histone H4 for Centromere Assembly

(2012) Emily A. Bassett et al.   DEVELOPMENTAL CELL

An inverse relationship to germline transcription defines centromeric chromatin in C. elegans

(2012) Reto Gassmann et al.   NATURE

Active transcription and essential role of RNA polymerase II at the centromere during mitosis

(2012) F. L. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells

(2012) A. J. Holland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional epialleles at an endogenous human centromere

(2012) K. A. Maloney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin

(2012) Silvia Dambacher et al.   Nucleus

Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A Nucleosomes

(2011) Karen E. Gascoigne et al.   CELL

Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells

(2011) Lori L. Sullivan et al.   CHROMOSOME RESEARCH

Cdk Activity Couples Epigenetic Centromere Inheritance to Cell Cycle Progression

(2011) Mariana C.C. Silva et al.   DEVELOPMENTAL CELL

CENP-C recruits M18BP1 to centromeres to promote CENP-A chromatin assembly

(2011) Ben Moree et al.   JOURNAL OF CELL BIOLOGY

HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore

(2011) Meghan C. Barnhart et al.   JOURNAL OF CELL BIOLOGY

XenopusHJURP and condensin II are required for CENP-A assembly

(2011) Rafael Bernad et al.   JOURNAL OF CELL BIOLOGY

In vitro centromere and kinetochore assembly on defined chromatin templates

(2011) Annika Guse et al.   NATURE

A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System

(2010) Mari Iwamoto et al.   CHEMISTRY & BIOLOGY

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore

(2010) Jan H Bergmann et al.   EMBO JOURNAL

Dual recognition of CENP-A nucleosomes is required for centromere assembly

(2010) Christopher W. Carroll et al.   JOURNAL OF CELL BIOLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

HJURP Is a Cell-Cycle-Dependent Maintenance and Deposition Factor of CENP-A at Centromeres

(2009) Elaine M. Dunleavy et al.   CELL

Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP

(2009) Daniel R. Foltz et al.   CELL

The life and miracles of kinetochores

(2009) Stefano Santaguida et al.   EMBO JOURNAL

Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N

(2009) Christopher W. Carroll et al.   NATURE CELL BIOLOGY

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

CCAN Makes Multiple Contacts with Centromeric DNA to Provide Distinct Pathways to the Outer Kinetochore

(2008) Tetsuya Hori et al.   CELL

Highly inclined thin illumination enables clear single-molecule imaging in cells

(2008) Makio Tokunaga et al.   NATURE METHODS

Epigenetic regulation of centromeric chromatin: old dogs, new tricks?

(2008) Robin C. Allshire et al.   NATURE REVIEWS GENETICS