High-resolution mapping of centromeric protein association using APEX-chromatin fibers

Linear assembly of a human centromere on the Y chromosome

(2018) Miten Jain et al.   NATURE BIOTECHNOLOGY

Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80

(2018) Marion E. Pesenti et al.   MOLECULAR CELL

Stepwise unfolding supports a subunit model for vertebrate kinetochores

(2017) Giulia Vargiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition

(2017) Lucie Y. Guo et al.   Nature Communications

CENPT bridges adjacent CENPA nucleosomes on young human α-satellite dimers

(2016) Jitendra Thakur et al.   GENOME RESEARCH

Insights from biochemical reconstitution into the architecture of human kinetochores

(2016) John R. Weir et al.   NATURE

Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2

(2016) Victoria Hung et al.   Nature Protocols

CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres

(2016) Samantha J Falk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Filling the Void: Proximity-Based Labeling of Proteins in Living Cells

(2016) Dae In Kim et al.   TRENDS IN CELL BIOLOGY

Inheritance of the CENP-A chromatin domain is spatially and temporally constrained at human centromeres

(2016) Justyne E. Ross et al.   Epigenetics & Chromatin

CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres

(2016) Samantha J Falk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere Function

(2015) Daniele Fachinetti et al.   DEVELOPMENTAL CELL

CENP-C is a blueprint for constitutive centromere–associated network assembly within human kinetochores

(2015) Kerstin Klare et al.   JOURNAL OF CELL BIOLOGY

Both tails and the centromere targeting domain of CENP-A are required for centromere establishment

(2015) Glennis A. Logsdon et al.   JOURNAL OF CELL BIOLOGY

CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly

(2015) N. Shono et al.   JOURNAL OF CELL SCIENCE

Identification of the Post-translational Modifications Present in Centromeric Chromatin

(2015) Aaron O. Bailey et al.   MOLECULAR & CELLULAR PROTEOMICS

The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface

(2015) Kara L. McKinley et al.   MOLECULAR CELL

The molecular basis for centromere identity and function

(2015) Kara L. McKinley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere

(2015) S. J. Falk et al.   SCIENCE

The Architecture of CCAN Proteins Creates a Structural Integrity to Resist Spindle Forces and Achieve Proper Intrakinetochore Stretch

(2014) Aussie Suzuki et al.   DEVELOPMENTAL CELL

Centromere reference models for human chromosomes X and Y satellite arrays

(2014) K. H. Miga et al.   GENOME RESEARCH

Directed evolution of APEX2 for electron microscopy and proximity labeling

(2014) Stephanie S Lam et al.   NATURE METHODS

A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle

(2014) C. Dornblut et al.   Open Biology

The Past, Present, and Future of Human Centromere Genomics

(2014) Megan Aldrup-MacDonald et al.   Genes

The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly

(2013) Tetsuya Hori et al.   JOURNAL OF CELL BIOLOGY

A two-step mechanism for epigenetic specification of centromere identity and function

(2013) Daniele Fachinetti et al.   NATURE CELL BIOLOGY

A Conserved Mechanism for Centromeric Nucleosome Recognition by Centromere Protein CENP-C

(2013) H. Kato et al.   SCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Functional epialleles at an endogenous human centromere

(2012) K. A. Maloney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells

(2011) Lori L. Sullivan et al.   CHROMOSOME RESEARCH

Direct Binding of Cenp-C to the Mis12 Complex Joins the Inner and Outer Kinetochore

(2011) Emanuela Screpanti et al.   CURRENT BIOLOGY

HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore

(2011) Meghan C. Barnhart et al.   JOURNAL OF CELL BIOLOGY

In vitro centromere and kinetochore assembly on defined chromatin templates

(2011) Annika Guse et al.   NATURE

Drosophila CENH3 Is Sufficient for Centromere Formation

(2011) M. J. Mendiburo et al.   SCIENCE

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore

(2010) Jan H Bergmann et al.   EMBO JOURNAL

Dual recognition of CENP-A nucleosomes is required for centromere assembly

(2010) Christopher W. Carroll et al.   JOURNAL OF CELL BIOLOGY

A super-resolution map of the vertebrate kinetochore

(2010) S. A. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissection of CENP-C–directed Centromere and Kinetochore Assembly

(2009) Kirstin J. Milks et al.   MOLECULAR BIOLOGY OF THE CELL

Condensin Regulates the Stiffness of Vertebrate Centromeres

(2009) Susana A. Ribeiro et al.   MOLECULAR BIOLOGY OF THE CELL

Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N

(2009) Christopher W. Carroll et al.   NATURE CELL BIOLOGY

CCAN Makes Multiple Contacts with Centromeric DNA to Provide Distinct Pathways to the Outer Kinetochore

(2008) Tetsuya Hori et al.   CELL

Epigenetic regulation of centromeric chromatin: old dogs, new tricks?

(2008) Robin C. Allshire et al.   NATURE REVIEWS GENETICS