DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres

Unexpected conformational variations of the human centromeric chromatin complex

(2018) Jitendra Thakur et al.   GENES & DEVELOPMENT

Defective RNA polymerase III is negatively regulated by the SUMO-Ubiquitin-Cdc48 pathway

(2018) Zheng Wang et al.   eLife

Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP

(2018) Ewelina Zasadzińska et al.   DEVELOPMENTAL CELL

Essential role for centromeric factors following p53 loss and oncogenic transformation

(2017) Dan Filipescu et al.   GENES & DEVELOPMENT

Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

(2017) Valerie A. Schneider et al.   GENOME RESEARCH

Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points

(2017) Yael Nechemia-Arbely et al.   JOURNAL OF CELL BIOLOGY

Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells

(2017) Roshan L. Shrestha et al.   Oncotarget

Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores

(2016) Arsen Petrovic et al.   CELL

Elevated expression of the centromere protein-A(CENP-A)-encoding gene as a prognostic and predictive biomarker in human cancers

(2016) Xia Sun et al.   INTERNATIONAL JOURNAL OF CANCER

Insights from biochemical reconstitution into the architecture of human kinetochores

(2016) John R. Weir et al.   NATURE

Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining

(2016) Peter Ly et al.   NATURE CELL BIOLOGY

Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy

(2016) Weiguo Zhang et al.   Nature Communications

CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly

(2016) Sebastian Hoffmann et al.   Cell Reports

Distinct Organization and Regulation of the Outer Kinetochore KMN Network Downstream of CENP-C and CENP-T

(2015) Florencia Rago et al.   CURRENT BIOLOGY

CENP-C is a blueprint for constitutive centromere–associated network assembly within human kinetochores

(2015) Kerstin Klare et al.   JOURNAL OF CELL BIOLOGY

A unique binding mode enables MCM2 to chaperone histones H3–H4 at replication forks

(2015) Hongda Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A unique binding mode enables MCM2 to chaperone histones H3–H4 at replication forks

(2015) Hongda Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional annotation of HOT regions in the human genome: implications for human disease and cancer

(2015) Hao Li et al.   Scientific Reports

A unique chromatin complex occupies young  -satellite arrays of human centromeres

(2015) J. G. Henikoff et al.   Science Advances

Centromere reference models for human chromosomes X and Y satellite arrays

(2014) K. H. Miga et al.   GENOME RESEARCH

Mislocalization of the Centromeric Histone Variant CenH3/CENP-A in Human Cells Depends on the Chaperone DAXX

(2014) Nicolas Lacoste et al.   MOLECULAR CELL

Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosome

(2014) Indri Erliandri et al.   NUCLEIC ACIDS RESEARCH

The quantitative architecture of centromeric chromatin

(2014) Dani L Bodor et al.   eLife

Octameric CENP-A Nucleosomes Are Present at Human Centromeres throughout the Cell Cycle

(2013) Abbas Padeganeh et al.   CURRENT BIOLOGY

The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly

(2013) Tetsuya Hori et al.   JOURNAL OF CELL BIOLOGY

A two-step mechanism for epigenetic specification of centromere identity and function

(2013) Daniele Fachinetti et al.   NATURE CELL BIOLOGY

The octamer is the major form of CENP-A nucleosomes at human centromeres

(2013) Dan Hasson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins

(2013) L. Teytelman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genomic and Transcriptomic Landscape of a HeLa Cell Line

(2013) Jonathan J. M. Landry et al.   G3-Genes Genomes Genetics

Cell-Cycle-Dependent Structural Transitions in the Human CENP-A Nucleosome In Vivo

(2012) Minh Bui et al.   CELL

Replicating centromeric chromatin: Spatial and temporal control of CENP-A assembly

(2012) Yael Nechemia-Arbely et al.   EXPERIMENTAL CELL RESEARCH

Sequences Associated with Centromere Competency in the Human Genome

(2012) K. E. Hayden et al.   MOLECULAR AND CELLULAR BIOLOGY

A Rapid FACS-Based Strategy to Isolate Human Gene Knockin and Knockout Clones

(2012) João F. Mata et al.   PLoS One

Functional epialleles at an endogenous human centromere

(2012) K. A. Maloney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A Nucleosomes

(2011) Karen E. Gascoigne et al.   CELL

Cdk Activity Couples Epigenetic Centromere Inheritance to Cell Cycle Progression

(2011) Mariana C.C. Silva et al.   DEVELOPMENTAL CELL

In vitro centromere and kinetochore assembly on defined chromatin templates

(2011) Annika Guse et al.   NATURE

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Epigenomics of centromere assembly and function

(2010) Kaitlin M Stimpson et al.   CURRENT OPINION IN CELL BIOLOGY

Dual recognition of CENP-A nucleosomes is required for centromere assembly

(2010) Christopher W. Carroll et al.   JOURNAL OF CELL BIOLOGY

A clustering approach for identification of enriched domains from histone modification ChIP-Seq data

(2009) Chongzhi Zang et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

HJURP Is a Cell-Cycle-Dependent Maintenance and Deposition Factor of CENP-A at Centromeres

(2009) Elaine M. Dunleavy et al.   CELL

Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP

(2009) Daniel R. Foltz et al.   CELL

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

(2009) R. S. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neocentromeres: New Insights into Centromere Structure, Disease Development, and Karyotype Evolution

(2008) Owen J. Marshall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CCAN Makes Multiple Contacts with Centromeric DNA to Provide Distinct Pathways to the Outer Kinetochore

(2008) Tetsuya Hori et al.   CELL

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY