Advanced engineering of third-generation lysins and formulation strategies for clinical applications
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Advanced engineering of third-generation lysins and formulation strategies for clinical applications
Authors
Keywords
-
Journal
CRITICAL REVIEWS IN MICROBIOLOGY
Volume 46, Issue 5, Pages 548-564
Publisher
Informa UK Limited
Online
2020-09-05
DOI
10.1080/1040841x.2020.1809346
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Construction and characterization of a chimeric lysin ClyV with improved bactericidal activity against Streptococcus agalactiae in vitro and in vivo
- (2020) Li Huang et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Antimicrobial activity of LysSS, a novel phage endolysin, against Acinetobacter baumannii and Pseudomonas aeruginosa
- (2020) Shukho Kim et al. Journal of Global Antimicrobial Resistance
- Recombinant spider silk coatings functionalized with enzymes targeting bacteria and biofilms
- (2020) Fredrik Seijsing et al. MicrobiologyOpen
- Targeting Hidden Pathogens: Cell-Penetrating Enzybiotics Eradicate Intracellular Drug-Resistant Staphylococcus aureus
- (2020) Christian Röhrig et al. mBio
- Intracellular Staphylococcus aureus persisters upon antibiotic exposure
- (2020) Frédéric Peyrusson et al. Nature Communications
- A Rapid Lysostaphin Production Approach and a Convenient Novel Lysostaphin Loaded Nano-emulgel; As a Sustainable Low-Cost Methicillin-Resistant Staphylococcus aureus Combating Platform
- (2020) Hanzada T. Nour El-Din et al. Biomolecules
- A VersaTile-driven platform for rapid hit-to-lead development of engineered lysins
- (2020) H. Gerstmans et al. Science Advances
- Encapsulation of the Antistaphylococcal Endolysin LysRODI in pH-Sensitive Liposomes
- (2020) Silvia Portilla et al. Antibiotics-Basel
- A Novel Phage PD-6A3, and Its Endolysin Ply6A3, With Extended Lytic Activity Against Acinetobacter baumannii
- (2019) Minle Wu et al. Frontiers in Microbiology
- Lysocins: Bioengineered Antimicrobials That Deliver Lysins across the Outer Membrane of Gram-Negative Bacteria
- (2019) Ryan D. Heselpoth et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The Influence of Dimerization on the Pharmacokinetics and Activity of an Antibacterial Enzyme Lysostaphin
- (2019) Alexander V. Grishin et al. MOLECULES
- Bioactive Silk Coatings Reduce the Adhesion of Staphylococcus aureus while Supporting Growth of Osteoblast-like Cells
- (2019) Linnea Nilebäck et al. ACS Applied Materials & Interfaces
- The bactericidal effect of lysostaphin coupled with liposomal vancomycin as a dual combating system applied directly on methicillin-resistant Staphylococcus aureus infected skin wounds in mice
- (2019) Fahimeh Hajiahmadi et al. International Journal of Nanomedicine
- Preparation and characterization of endolysin-containing liposomes and evaluation of their antimicrobial activities against gram-negative bacteria
- (2019) Jaewoo Bai et al. ENZYME AND MICROBIAL TECHNOLOGY
- Fusion of Lysostaphin to an Albumin Binding Domain Prolongs Its Half-Life and Bactericidal Activity in the Systemic Circulation
- (2019) Alexander V. Grishin et al. MOLECULES
- Exebacase demonstrates in vitro synergy with a broad range of antibiotics against both methicillin-resistant and methicillin-susceptible Staphylococcus aureus
- (2019) Aubrey Watson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Comprehensive evaluation of chitosan nanoparticle based phage lysin delivery system; a novel approach to counter S. pneumoniae infections
- (2019) Vijay Singh Gondil et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The global preclinical antibacterial pipeline
- (2019) Ursula Theuretzbacher et al. NATURE REVIEWS MICROBIOLOGY
- Synergistic Anti-Staphylococcal Activity Of Niosomal Recombinant Lysostaphin-LL-37
- (2019) Somayeh Sadeghi et al. International Journal of Nanomedicine
- Synthetic biology of modular endolysins
- (2018) Hans Gerstmans et al. BIOTECHNOLOGY ADVANCES
- Preparation, characterization and efficacy of lysostaphin-chitosan gel against Staphylococcus aureus
- (2018) Sai Nithya et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Skin wound healing in humans and mice: Challenges in translational research
- (2018) Helena D. Zomer et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Determination of Pathogens in Postoperative Wound Infection After Surgically Reduced Calcaneal Fractures and Implications for Prophylaxis and Treatment
- (2018) Manouk Backes et al. Journal of Foot & Ankle Surgery
- Hydrogel delivery of lysostaphin eliminates orthopedic implant infection byStaphylococcus aureusand supports fracture healing
- (2018) Christopher T. Johnson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Ointment Consisting of the Phage Lysin LysGH15 and Apigenin for Decolonization of Methicillin-Resistant Staphylococcus aureus from Skin Wounds
- (2018) Mengjun Cheng et al. Viruses-Basel
- Effects of a Chimeric Lysin against Planktonic and Sessile Enterococcus faecalis Hint at Potential Application in Endodontic Therapy
- (2018) Wuyou Li et al. Viruses-Basel
- Effects of Phage Endolysin SAL200 Combined with Antibiotics on Staphylococcus aureus Infection
- (2018) Nak-Hyun Kim et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Phage Lysin Fused to a Cell-Penetrating Peptide Kills Intracellular Methicillin-Resistant Staphylococcus aureus in Keratinocytes and Has Potential as a Treatment for Skin Infections in Mice
- (2018) ZhaoFei Wang et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Nanoemulsions in drug delivery: formulation to medical application
- (2018) Hossam H Tayeb et al. Nanomedicine
- Analysis of the clinical antibacterial and antituberculosis pipeline
- (2018) Ursula Theuretzbacher et al. LANCET INFECTIOUS DISEASES
- Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis
- (2018) Alessandro Cassini et al. LANCET INFECTIOUS DISEASES
- Engineering Microbial Living Therapeutics: The Synthetic Biology Toolbox
- (2018) Danielle B. Pedrolli et al. TRENDS IN BIOTECHNOLOGY
- Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal
- (2018) Marek Harhala et al. Viruses-Basel
- Improved Biodistribution and Extended Serum Half-Life of a Bacteriophage Endolysin by Albumin Binding Domain Fusion
- (2018) Johan Seijsing et al. Frontiers in Microbiology
- Thermally triggered release of the bacteriophage endolysin CHAPK and the bacteriocin lysostaphin for the control of methicillin resistant Staphylococcus aureus (MRSA)
- (2017) Hollie Hathaway et al. JOURNAL OF CONTROLLED RELEASE
- Pseudomonas predators: understanding and exploiting phage–host interactions
- (2017) Jeroen De Smet et al. NATURE REVIEWS MICROBIOLOGY
- A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
- (2017) Chia-Jung Chang et al. Nature Communications
- Effect of aerobic exercise and diet on liver fat in pre-diabetic patients with non-alcoholic-fatty-liver-disease: A randomized controlled trial
- (2017) Sulin Cheng et al. Scientific Reports
- A novel chimeric lysin with robust antibacterial activity against planktonic and biofilm methicillin-resistant Staphylococcus aureus
- (2017) Hang Yang et al. Scientific Reports
- Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii
- (2016) Valerie Defraine et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Pharmacokinetics of the phage endolysin-based candidate drug SAL200 in monkeys and its appropriate intravenous dosing period
- (2016) Soo Youn Jun et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- T4 lysozyme fused with cellulose-binding module for antimicrobial cellulosic wound dressing materials
- (2016) A. Abouhmad et al. JOURNAL OF APPLIED MICROBIOLOGY
- PEGylation of Biopharmaceuticals: A Review of Chemistry and Nonclinical Safety Information of Approved Drugs
- (2016) Peter L. Turecek et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Alternatives to antibiotics—a pipeline portfolio review
- (2016) Lloyd Czaplewski et al. LANCET INFECTIOUS DISEASES
- A secreted bacterial peptidoglycan hydrolase enhances tolerance to enteric pathogens
- (2016) K. J. Rangan et al. SCIENCE
- A bacteriophage endolysin that eliminates intracellular streptococci
- (2016) Yang Shen et al. eLife
- Triple-acting Lytic Enzyme Treatment of Drug-Resistant and Intracellular Staphylococcus aureus
- (2016) Stephen C. Becker et al. Scientific Reports
- LysGH15 kills Staphylococcus aureus without being affected by the humoral immune response or inducing inflammation
- (2016) Lei Zhang et al. Scientific Reports
- Incidence of skin and soft tissue infections in ambulatory and inpatient settings, 2005–2010
- (2015) Loren G. Miller et al. BMC INFECTIOUS DISEASES
- Depletion of T Cell Epitopes in Lysostaphin Mitigates Anti-Drug Antibody Response and Enhances Antibacterial Efficacy In Vivo
- (2015) Hongliang Zhao et al. CHEMISTRY & BIOLOGY
- Breaking barriers: expansion of the use of endolysins as novel antibacterials against Gram-negative bacteria
- (2015) Yves Briers et al. Future Microbiology
- Apigenin-7-Glycoside Prevents LPS-Induced Acute Lung Injury via Downregulation of Oxidative Enzyme Expression and Protein Activation through Inhibition of MAPK Phosphorylation
- (2015) Kun-Cheng Li et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epidemiology of Clinically Relevant Bacterial Pathogens in a Burn Center in the Netherlands Between 2005 and 2011
- (2015) Bram M. W. Diederen et al. Journal of Burn Care & Research
- Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes
- (2015) Sinu Paul et al. JOURNAL OF IMMUNOLOGICAL METHODS
- NonstableStaphylococcus aureusSmall-Colony Variants Are Induced by Low pH and Sensitized to Antimicrobial Therapy by Phagolysosomal Alkalinization
- (2015) Nadja Leimer et al. JOURNAL OF INFECTIOUS DISEASES
- Antibacterial and Antibiofilm Surfaces through Polydopamine-Assisted Immobilization of Lysostaphin as an Antibacterial Enzyme
- (2015) Gil Yeroslavsky et al. LANGMUIR
- Community-acquired pneumonia: An overview
- (2015) Lionel A. Mandell POSTGRADUATE MEDICINE
- Methicillin-Resistant Staphylococcus aureus Adaptation to Human Keratinocytes
- (2015) Grace Soong et al. mBio
- Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance
- (2015) Kristina Blazanovic et al. Molecular Therapy-Methods & Clinical Development
- Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa
- (2014) Yves Briers et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Animal models in burn research
- (2014) A. Abdullahi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Chitosan-protein scaffolds loaded with lysostaphin as potential antistaphylococcal wound dressing materials
- (2014) P. Szweda et al. JOURNAL OF APPLIED MICROBIOLOGY
- Effective Removal of Staphylococcal Biofilms by the Endolysin LysH5
- (2014) Diana Gutiérrez et al. PLoS One
- Lysostaphin-Coated Titan-Implants Preventing Localized Osteitis by Staphylococcus aureus in a Mouse Model
- (2014) Ceylan D. Windolf et al. PLoS One
- Engineered Endolysin-Based "Artilysins" To Combat Multidrug-Resistant Gram-Negative Pathogens
- (2014) Y. Briers et al. mBio
- Site-Specific N-Glycosylation of Caprine Lysostaphin Restricts its Bacteriolytic Activity TowardStaphylococcus Aureus
- (2013) Ching-Ying Huang et al. ANIMAL BIOTECHNOLOGY
- Pathways of Antigen Processing
- (2013) Janice S. Blum et al. Annual Review of Immunology
- Novel Bacteriophage Lysin with Broad Lytic Activity Protects against Mixed Infection by Streptococcus pyogenes and Methicillin-Resistant Staphylococcus aureus
- (2013) Daniel B. Gilmer et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Expression and delivery of an endolysin to combat Clostridium perfringens
- (2013) Teresa Gervasi et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia
- (2013) J. M. Doehn et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Structure-Guided Deimmunization of Therapeutic Proteins
- (2013) Andrew S. Parker et al. JOURNAL OF COMPUTATIONAL BIOLOGY
- Combination Therapy With Lysin CF-301 and Antibiotic Is Superior to Antibiotic Alone for Treating Methicillin-Resistant Staphylococcus aureus–Induced Murine Bacteremia
- (2013) Raymond Schuch et al. JOURNAL OF INFECTIOUS DISEASES
- The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells
- (2013) William R Heath et al. NATURE IMMUNOLOGY
- Platforms for antibiotic discovery
- (2013) Kim Lewis NATURE REVIEWS DRUG DISCOVERY
- Src kinase is a direct target of apigenin against UVB-induced skin inflammation
- (2012) Sanguine Byun et al. CARCINOGENESIS
- Effect of PEGylation on Protein Hydrodynamics
- (2012) Yatin R. Gokarn et al. MOLECULAR PHARMACEUTICS
- Structural engineering of a phage lysin that targets Gram-negative pathogens
- (2012) P. Lukacik et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biomaterial-Associated Infection: Locating the Finish Line in the Race for the Surface
- (2012) H. J. Busscher et al. Science Translational Medicine
- Effects of potassium apigenin and verbena extract on the wound healing process of SKH-1 mouse skin
- (2012) Pia Lopez-Jornet et al. International Wound Journal
- Inhibition of Staphylococcus aureus by Lysostaphin-Expressing Lactobacillus plantarum WCFS1 in a Modified Genital Tract Secretion Medium
- (2011) Huanli Liu et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Antibacterial activity of Acinetobacter baumannii phage ϕAB2 endolysin (LysAB2) against both Gram-positive and Gram-negative bacteria
- (2011) Meng-Jiun Lai et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Lysostaphin-functionalized cellulose fibers with antistaphylococcal activity for wound healing applications
- (2011) Jianjun Miao et al. BIOMATERIALS
- Strategies for extended serum half-life of protein therapeutics
- (2011) Roland E Kontermann CURRENT OPINION IN BIOTECHNOLOGY
- A stable phage lysin (Cpl-1) dimer with increased antipneumococcal activity and decreased plasma clearance
- (2011) Gregory Resch et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- PEGylating a bacteriophage endolysin inhibits its bactericidal activity
- (2011) Gregory Resch et al. AMB Express
- Biology of Clostridium difficile: Implications for Epidemiology and Diagnosis
- (2010) Carroll Karen C. et al. Annual Review of Microbiology
- A Novel Chimeric Lysin Shows Superiority to Mupirocin for Skin Decolonization of Methicillin-Resistant and -SensitiveStaphylococcus aureusStrains
- (2010) Mina Pastagia et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Glycosylation of Therapeutic Proteins
- (2010) Ricardo J. Solá et al. BIODRUGS
- Cellulose Nanocrystals: Chemistry, Self-Assembly, and Applications
- (2010) Youssef Habibi et al. CHEMICAL REVIEWS
- Discovery and basic pharmacology of erythropoiesis-stimulating agents (ESAs), including the hyperglycosylated ESA, darbepoetin alfa: an update of the rationale and clinical impact
- (2010) Zoltán Kiss et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Novel insights into the epidemiology of Clostridium perfringens type A food poisoning
- (2010) Miia Lindström et al. FOOD MICROBIOLOGY
- Predicting MHC-II Binding Affinity Using Multiple Instance Regression
- (2010) Yasser EL-Manzalawy et al. IEEE-ACM Transactions on Computational Biology and Bioinformatics
- Surgical Approaches to Create Murine Models of Human Wound Healing
- (2010) Victor W. Wong et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Highly glycosylated human alpha interferon: An insight into a new therapeutic candidate
- (2010) Natalia Ceaglio et al. JOURNAL OF BIOTECHNOLOGY
- A Clinical Investigation into the Relationship between Increased Periwound Skin Temperature and Local Wound Infection in Patients with Chronic Leg Ulcers
- (2010) Marjorie Fierheller et al. Advances in Skin & Wound Care
- LysK CHAP endopeptidase domain is required for lysis of live staphylococcal cells
- (2009) Stephen C. Becker et al. FEMS MICROBIOLOGY LETTERS
- Staphylococcus epidermidis — the 'accidental' pathogen
- (2009) Michael Otto NATURE REVIEWS MICROBIOLOGY
- National Trends in Ambulatory Visits and Antibiotic Prescribing for Skin and Soft-Tissue Infections
- (2008) Adam L. Hersh ARCHIVES OF INTERNAL MEDICINE
- Engineering of a femtomolar affinity binding protein to human serum albumin
- (2008) A. Jonsson et al. PROTEIN ENGINEERING DESIGN & SELECTION
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started