Pseudomonas predators: understanding and exploiting phage–host interactions

Virus taxonomy in the age of metagenomics

(2017) Peter Simmonds et al.   NATURE REVIEWS MICROBIOLOGY

Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii

(2016) Valerie Defraine et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phage Therapy Is Effective in a Mouse Model of Bacterial Equine Keratitis

(2016) Takaaki Furusawa et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

From endolysins to Artilysin(R)s: novel enzyme-based approaches to kill drug-resistant bacteria

(2016) H. Gerstmans et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Adaptation to abiotic conditions drives local adaptation in bacteria and viruses coevolving in heterogeneous environments

(2016) Florien A. Gorter et al.   Biology Letters

Biosynthesis and Function of Modified Bases in Bacteria and Their Viruses

(2016) Peter Weigele et al.   CHEMICAL REVIEWS

Phage Therapy in Bacterial Infections Treatment: One Hundred Years After the Discovery of Bacteriophages

(2016) Agata Anna Cisek et al.   CURRENT MICROBIOLOGY

Cryptic prophages as targets for drug development

(2016) Xiaoxue Wang et al.   DRUG RESISTANCE UPDATES

Temperate phages enhance pathogen fitness in chronic lung infection

(2016) Emily V Davies et al.   ISME Journal

Prophages mediate defense against phage infection through diverse mechanisms

(2016) Joseph Bondy-Denomy et al.   ISME Journal

High coverage metabolomics analysis reveals phage-specific alterations to Pseudomonas aeruginosa physiology during infection

(2016) Jeroen De Smet et al.   ISME Journal

Phospholipid vesicles encapsulated bacteriophage: A novel approach to enhance phage biodistribution

(2016) S. Singla et al.   JOURNAL OF VIROLOGICAL METHODS

Alternatives to antibiotics—a pipeline portfolio review

(2016) Lloyd Czaplewski et al.   LANCET INFECTIOUS DISEASES

Genetically Engineered Phages: a Review of Advances over the Last Decade

(2016) Diana P. Pires et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Pseudolysogeny and sequential mutations build multiresistance to virulent bacteriophages in Pseudomonas aeruginosa

(2016) Libera Latino et al.   MICROBIOLOGY-SGM

Pf4 bacteriophage produced by Pseudomonas aeruginosa inhibits Aspergillus fumigatus metabolism via iron sequestration

(2016) Jack C. Penner et al.   MICROBIOLOGY-SGM

The bacteriophage-derived transcriptional regulator, LscR, activates the expression of levansucrase genes inPseudomonas syringae

(2016) Khaled Abdallah et al.   MOLECULAR MICROBIOLOGY

Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections

(2016) Sharon S. Y. Leung et al.   PHARMACEUTICAL RESEARCH

Temperate phages both mediate and drive adaptive evolution in pathogen biofilms

(2016) Emily V. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies

(2016) Hélène Chabas et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Viral interference of the bacterial RNA metabolism machinery

(2016) Tom Dendooven et al.   RNA Biology

Explosive cell lysis as a mechanism for the biogenesis of bacterial membrane vesicles and biofilms

(2016) Lynne Turnbull et al.   Nature Communications

Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa

(2016) Anne Chevallereau et al.   PLoS Genetics

Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome

(2016) An Van den Bossche et al.   eLife

Characterization of Novel Bacteriophages for Biocontrol of Bacterial Blight in Leek Caused by Pseudomonas syringae pv. porri

(2016) Sofie Rombouts et al.   Frontiers in Microbiology

Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species

(2016) April Pawluk et al.   Nature Microbiology

Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa

(2016) Benjamin K. Chan et al.   Scientific Reports

A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections

(2016) Katarzyna Danis-Wlodarczyk et al.   Scientific Reports

In vitro and in vivo antibacterial activity of environmental bacteriophages against Pseudomonas aeruginosa strains from cystic fibrosis patients

(2015) Tomasz Olszak et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Filamentous Bacteriophage Promote Biofilm Assembly and Function

(2015) Patrick R. Secor et al.   Cell Host & Microbe

Parasite Exposure Drives Selective Evolution of Constitutive versus Inducible Defense

(2015) Edze R. Westra et al.   CURRENT BIOLOGY

Assessing phage therapy against Pseudomonas aeruginosa using a Galleria mellonella infection model

(2015) M.L. Beeton et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Bacteriophage Delivery by Nebulization and Efficacy Against Phenotypically DiversePseudomonas aeruginosafrom Cystic Fibrosis Patients

(2015) Jaspreet Singh Sahota et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Genes Required for Free Phage Production are Essential forPseudomonas aeruginosaChronic Lung Infections

(2015) Andrée-Ann Lemieux et al.   JOURNAL OF INFECTIOUS DISEASES

Dark Matter of the Biosphere: the Amazing World of Bacteriophage Diversity

(2015) Graham F. Hatfull   JOURNAL OF VIROLOGY

Coevolution with Bacteriophages Drives Genome-Wide Host Evolution and Constrains the Acquisition of Abiotic-Beneficial Mutations

(2015) Pauline D. Scanlan et al.   MOLECULAR BIOLOGY AND EVOLUTION

Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins

(2015) Joseph Bondy-Denomy et al.   NATURE

A new perspective on lysogeny: prophages as active regulatory switches of bacteria

(2015) Ron Feiner et al.   NATURE REVIEWS MICROBIOLOGY

Quality and Safety Requirements for Sustainable Phage Therapy Products

(2015) Jean-Paul Pirnay et al.   PHARMACEUTICAL RESEARCH

Phylogenetic Distribution of CRISPR-Cas Systems in Antibiotic-Resistant Pseudomonas aeruginosa

(2015) Alex van Belkum et al.   mBio

Mammalian Host-Versus-Phage immune response determines phage fate in vivo

(2015) Katarzyna Hodyra-Stefaniak et al.   Scientific Reports

Downstream processing and chromatography based analytical methods for production of vaccines, gene therapy vectors, and bacteriophages

(2015) Petra Kramberger et al.   Human Vaccines & Immunotherapeutics

Viral Transmission Dynamics at Single-Cell Resolution Reveal Transiently Immune Subpopulations Caused by a Carrier State Association

(2015) William Cenens et al.   PLoS Genetics

Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

(2015) Luca Freschi et al.   Frontiers in Microbiology

Antibacterial phage ORFans of Pseudomonas aeruginosa phage LUZ24 reveal a novel MvaT inhibiting protein

(2015) Jeroen Wagemans et al.   Frontiers in Microbiology

Core and accessory genome architecture in a group of Pseudomonas aeruginosa Mu-like phages

(2015) Adrián Cazares et al.   BMC GENOMICS

Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa

(2014) Yves Briers et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Functional elucidation of antibacterial phage ORFans targetingPseudomonas aeruginosa

(2014) Jeroen Wagemans et al.   CELLULAR MICROBIOLOGY

Effectiveness of bacteriophages in the sputum of cystic fibrosis patients

(2014) E. Saussereau et al.   CLINICAL MICROBIOLOGY AND INFECTION

Bacteriophage-based synthetic biology for the study of infectious diseases

(2014) Robert J Citorik et al.   CURRENT OPINION IN MICROBIOLOGY

FreeingPseudomonas putida KT2440 of its proviral load strengthens endurance to environmental stresses

(2014) Esteban Martínez-García et al.   ENVIRONMENTAL MICROBIOLOGY

Instability of bacteriophages in spray-dried trehalose powders is caused by crystallization of the matrix

(2014) Dieter Vandenheuvel et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Phages can constrain protist predation-driven attenuation of Pseudomonas aeruginosa virulence in multienemy communities

(2014) Ville-Petri Friman et al.   ISME Journal

Lytic activity by temperate phages of Pseudomonas aeruginosa in long-term cystic fibrosis chronic lung infections

(2014) Chloe E James et al.   ISME Journal

Systematic Identification of Hypothetical Bacteriophage Proteins Targeting Key Protein Complexes of Pseudomonas aeruginosa

(2014) An Van den Bossche et al.   JOURNAL OF PROTEOME RESEARCH

Development of Giant Bacteriophage  KZ Is Independent of the Host Transcription Apparatus

(2014) P.-J. Ceyssens et al.   JOURNAL OF VIROLOGY

Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

(2014) Robert J Citorik et al.   NATURE BIOTECHNOLOGY

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials

(2014) David Bikard et al.   NATURE BIOTECHNOLOGY

A phage protein that inhibits the bacterial ATPase required for type IV pilus assembly

(2014) I.-Y. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phage Neutralization by Sera of Patients Receiving Phage Therapy

(2014) Marzanna Łusiak-Szelachowska et al.   VIRAL IMMUNOLOGY

Engineered Endolysin-Based "Artilysins" To Combat Multidrug-Resistant Gram-Negative Pathogens

(2014) Y. Briers et al.   mBio

A New Group of Phage Anti-CRISPR Genes Inhibits the Type I-E CRISPR-Cas System of Pseudomonas aeruginosa

(2014) A. Pawluk et al.   mBio

Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa

(2014) Shuai Le et al.   Scientific Reports

PredictingIn VivoEfficacy of Therapeutic Bacteriophages Used To Treat Pulmonary Infections

(2013) Marine Henry et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evolution of Pseudomonas aeruginosa Virulence as a Result of Phage Predation

(2013) Zeinab Hosseinidoust et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Formation of biofilms under phage predation: considerations concerning a biofilm increase

(2013) Zeinab Hosseinidoust et al.   BIOFOULING

Novel bacteriophage therapy for controlling metallo-beta-lactamase producing Pseudomonas aeruginosa infection in Catfish

(2013) Krishna Khairnar et al.   BMC Veterinary Research

Feasibility of spray drying bacteriophages into respirable powders to combat pulmonary bacterial infections

(2013) Dieter Vandenheuvel et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Structure and function of a cyanophage-encoded peptide deformylase

(2013) Jeremy A Frank et al.   ISME Journal

Coevolution with phages does not influence the evolution of bacterial mutation rates in soil

(2013) Pedro Gómez et al.   ISME Journal

The D3 Bacteriophage  -Polymerase Inhibitor (Iap) Peptide Disrupts O-Antigen Biosynthesis through Mimicry of the Chain Length Regulator Wzz in Pseudomonas aeruginosa

(2013) V. L. Taylor et al.   JOURNAL OF BACTERIOLOGY

Bacterial motility confers fitness advantage in the presence of phages

(2013) T. B. Taylor et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Structure of the Tubulin/FtsZ-Like Protein TubZ from Pseudomonas Bacteriophage ΦKZ

(2013) Christopher H.S. Aylett et al.   JOURNAL OF MOLECULAR BIOLOGY

Stability and purity of a bacteriophage cocktail preparation for nebulizer delivery

(2013) C.J. Cooper et al.   LETTERS IN APPLIED MICROBIOLOGY

Revenge of the phages: defeating bacterial defences

(2013) Julie E. Samson et al.   NATURE REVIEWS MICROBIOLOGY

Mapping the Tail Fiber as the Receptor Binding Protein Responsible for Differential Host Specificity of Pseudomonas aeruginosa Bacteriophages PaP1 and JG004

(2013) Shuai Le et al.   PLoS One

Self-organization of bacterial biofilms is facilitated by extracellular DNA

(2013) E. S. Gloag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A non-bacterial transcription factor inhibits bacterial transcription by a multipronged mechanism

(2013) Carol Sheppard et al.   RNA Biology

Metabolic Engineering: Past and Future

(2013) Benjamin M. Woolston et al.   Annual Review of Chemical and Biomolecular Engineering

A Multifaceted Study of Pseudomonas aeruginosa Shutdown by Virulent Podovirus LUZ19

(2013) R. Lavigne et al.   mBio

Importance of prophages to evolution and virulence of bacterial pathogens

(2013) Louis-Charles Fortier et al.   Virulence

Expression of a Novel P22 ORFan Gene Reveals the Phage Carrier State in Salmonella Typhimurium

(2013) William Cenens et al.   PLoS Genetics

Metabonomic Study of Host–Phage Interaction by Nuclear Magnetic Resonance- and Statistical Total Correlation Spectroscopy-Based Analysis

(2012) Kanchan Sonkar et al.   ANALYTICAL CHEMISTRY

High Diversity and Novel Species of Pseudomonas aeruginosa Bacteriophages

(2012) Omar Sepúlveda-Robles et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Phage Tubulin Assembles Dynamic Filaments by an Atypical Mechanism to Center Viral DNA within the Host Cell

(2012) James A. Kraemer et al.   CELL

Silencing of foreign DNA in bacteria

(2012) Sabrina S Ali et al.   CURRENT OPINION IN MICROBIOLOGY

Effects of predation on real-time host-parasite coevolutionary dynamics

(2012) Ville-Petri Friman et al.   ECOLOGY LETTERS

Phages limit the evolution of bacterial antibiotic resistance in experimental microcosms

(2012) Quan-Guo Zhang et al.   Evolutionary Applications

The CRISPR/Cas Adaptive Immune System of Pseudomonas aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages

(2012) K. C. Cady et al.   JOURNAL OF BACTERIOLOGY

Basis for the Essentiality of H-NS Family Members in Pseudomonas aeruginosa

(2012) Sandra Castang et al.   JOURNAL OF BACTERIOLOGY

Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system

(2012) Joe Bondy-Denomy et al.   NATURE

Identification of EPS-degrading activity within the tail spikes of the novel Pseudomonas putida phage AF

(2012) Anneleen Cornelissen et al.   VIROLOGY

CIM® monolithic anion-exchange chromatography as a useful alternative to CsCl gradient purification of bacteriophage particles

(2012) Evelien M. Adriaenssens et al.   VIROLOGY

Host RNA polymerase inhibitors encoded by ϕKMV-like phages of pseudomonas

(2012) Evgeny Klimuk et al.   VIROLOGY

Coevolving parasites enhance the diversity-decreasing effect of dispersal

(2011) T. Vogwill et al.   Biology Letters

Host-parasite coevolutionary arms races give way to fluctuating selection

(2011) Alex R. Hall et al.   ECOLOGY LETTERS

Co-evolution with lytic phage selects for the mucoid phenotype of Pseudomonas fluorescens SBW25

(2011) Pauline Deirdre Scanlan et al.   ISME Journal

Comparative metagenomics of microbial traits within oceanic viral communities

(2011) Itai Sharon et al.   ISME Journal

Recent advances in bacteriophage therapy: how delivery routes, formulation, concentration and timing influence the success of phage therapy

(2011) Elizabeth M. Ryan et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The novel Pseudomonas aeruginosa two-component regulator BfmR controls bacteriophage-mediated lysis and DNA release during biofilm development through PhdA

(2011) Olga E. Petrova et al.   MOLECULAR MICROBIOLOGY

Consider something viral in your research

(2011) Forest Rohwer et al.   NATURE REVIEWS MICROBIOLOGY

Pulmonary Bacteriophage Therapy on Pseudomonas aeruginosa Cystic Fibrosis Strains: First Steps Towards Treatment and Prevention

(2011) Eric Morello et al.   PLoS One

The T7-Related Pseudomonas putida Phage φ15 Displays Virion-Associated Biofilm Degradation Properties

(2011) Anneleen Cornelissen et al.   PLoS One

Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism

(2011) L. R. Thompson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteria-Phage Antagonistic Coevolution in Soil

(2011) P. Gomez et al.   SCIENCE

Pseudomonas aeruginosa: all roads lead to resistance

(2011) Elena B.M. Breidenstein et al.   TRENDS IN MICROBIOLOGY

Bacteriophages and their genomes

(2011) Graham F Hatfull et al.   Current Opinion in Virology

Bacteriophages and cancer

(2010) Paulina Budynek et al.   ARCHIVES OF MICROBIOLOGY

The virus as metabolic engineer

(2010) Nathaniel D. Maynard et al.   Biotechnology Journal

Genomic analysis of oceanic cyanobacterial myoviruses compared with T4-like myoviruses from diverse hosts and environments

(2010) Matthew B. Sullivan et al.   ENVIRONMENTAL MICROBIOLOGY

Bacteriophages ofPseudomonas

(2010) Pieter-Jan Ceyssens et al.   Future Microbiology

Bacteriophage endolysins: A novel anti-infective to control Gram-positive pathogens

(2010) Vincent A. Fischetti   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The Accessory Genome of Pseudomonas aeruginosa

(2010) V. L. Kung et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Pseudomonas aeruginosa generalized transducing phage  PA3 is a new member of the  KZ-like group of 'jumbo' phages, and infects model laboratory strains and clinical isolates from cystic fibrosis patients

(2010) R. Monson et al.   MICROBIOLOGY-SGM

Genetic basis of infectivity evolution in a bacteriophage

(2010) PAULINE D. SCANLAN et al.   MOLECULAR ECOLOGY

A phage-encoded inhibitor of Escherichia coli DNA replication targets the DNA polymerase clamp loader

(2010) Sho T. Yano et al.   MOLECULAR MICROBIOLOGY

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

(2010) Josiane E. Garneau et al.   NATURE

Antagonistic coevolution accelerates molecular evolution

(2010) Steve Paterson et al.   NATURE

The Phage Therapy Paradigm: Prêt-à-Porter or Sur-mesure?

(2010) Jean-Paul Pirnay et al.   PHARMACEUTICAL RESEARCH

Bacteriophages as potential new therapeutics to replace or supplement antibiotics

(2010) Mzia Kutateladze et al.   TRENDS IN BIOTECHNOLOGY

Topical treatment of Pseudomonas aeruginosa otitis of dogs with a bacteriophage mixture: A before/after clinical trial

(2010) Catherine Hawkins et al.   VETERINARY MICROBIOLOGY

Classification of Myoviridae bacteriophages using protein sequence similarity

(2009) Rob Lavigne et al.   BMC MICROBIOLOGY

A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistantPseudomonas aeruginosa; a preliminary report of efficacy

(2009) A. Wright et al.   CLINICAL OTOLARYNGOLOGY

Survey ofPseudomonas aeruginosaand its phages:de novopeptide sequencing as a novel tool to assess the diversity of worldwide collected viruses

(2009) Pieter-Jan Ceyssens et al.   ENVIRONMENTAL MICROBIOLOGY

The role of interactions between phage and bacterial proteins within the infected cell: a diverse and puzzling interactome

(2009) Bart Roucourt et al.   ENVIRONMENTAL MICROBIOLOGY

Occurrence of phosphate acquisition genes inProchlorococcuscells from different ocean regions

(2009) Adam C. Martiny et al.   ENVIRONMENTAL MICROBIOLOGY

Bacteriophage-derived enzyme that depolymerizes the alginic acid capsule associated with cystic fibrosis isolates ofPseudomonas aeruginosa

(2009) T. Glonti et al.   JOURNAL OF APPLIED MICROBIOLOGY

Quality-Controlled Small-Scale Production of a Well-Defined Bacteriophage Cocktail for Use in Human Clinical Trials

(2009) Maya Merabishvili et al.   PLoS One

Identification and investigation of ORFans in the viral world

(2008) Yanbin Yin et al.   BMC GENOMICS

The biofilm life cycle and virulence of Pseudomonas aeruginosa are dependent on a filamentous prophage

(2008) Scott A Rice et al.   ISME Journal

Global-scale processes with a nanoscale drive: the role of marine viruses

(2008) Corina P D Brussaard et al.   ISME Journal

Phage therapy experience at the Eliava Institute

(2008) M. Kutateladze et al.   MEDECINE ET MALADIES INFECTIEUSES

H-NS family members function coordinately in an opportunistic pathogen

(2008) S. Castang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unifying classical and molecular taxonomic classification: analysis of the Podoviridae using BLASTP-based tools

(2008) Rob Lavigne et al.   RESEARCH IN MICROBIOLOGY