BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF

BMP‐2 Signaling and Mechanotransduction Synergize to Drive Osteogenic Differentiation via YAP/TAZ

(2020) Qiang Wei et al.   Advanced Science

BMP2 secretion from hepatocellular carcinoma cell HepG2 enhances angiogenesis and tumor growth in endothelial cells via activation of the MAPK/p38 signaling pathway

(2019) Peng-Cheng Feng et al.   Stem Cell Research & Therapy

Fox proteins are modular competency factors for facial cartilage and tooth specification

(2018) Pengfei Xu et al.   DEVELOPMENT

Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms

(2018) Tiffany B. Duong et al.   DEVELOPMENTAL BIOLOGY

Hippo signaling determines the number of venous pole cells that originate from the anterior lateral plate mesoderm in zebrafish

(2018) Hajime Fukui et al.   eLife

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

(2018) Filipa Neto et al.   eLife

Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumor Microenvironment: Implications for Immunotherapy

(2018) Adriana Albini et al.   Frontiers in Immunology

Epithelioid Hemangioendothelioma as a Model of YAP/TAZ-Driven Cancer: Insights from a Rare Fusion Sarcoma

(2018) John Lamar et al.   Cancers

The role of YAP/TAZ activity in cancer metabolic reprogramming

(2018) Xiaodong Zhang et al.   Molecular Cancer

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

Beyond endothelial cells: Vascular endothelial growth factors in heart, vascular anomalies and placenta

(2018) Johanna P. Laakkonen et al.   VASCULAR PHARMACOLOGY

Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up

(2017) Juha Hartikainen et al.   EUROPEAN HEART JOURNAL

Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk vs. tip cell competence

(2017) Andreas Benn et al.   FASEB JOURNAL

YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation

(2017) Jongshin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions

(2017) Henri Niskanen et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial InfarctionCLINICAL PERSPECTIVE

(2017) Minna U. Kaikkonen et al.   Circulation-Cardiovascular Genetics

Growth Differentiation Factor 6 Promotes Vascular Stability by Restraining Vascular Endothelial Growth Factor Signaling

(2017) Shlomo Krispin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8

(2016) Johanna P. Laakkonen et al.   ANGIOGENESIS

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6

(2016) Kevin P. Mouillesseaux et al.   Nature Communications

RhBMP-2 Activates Hippo Signaling through RASSF1 in Esophageal Cancer Cells

(2016) Soo Mi Kim et al.   Scientific Reports

Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways

(2016) Wei-han Zuo et al.   Scientific Reports

Recent Advancements in Cardiovascular Gene Therapy and Vascular Biology

(2015) Johanna P. Laakkonen et al.   HUMAN GENE THERAPY

Expression of theCTCFLGene during Mouse Embryogenesis Causes Growth Retardation, Postnatal Lethality, and Dysregulation of the Transforming Growth Factor β Pathway

(2015) Leyla Sati et al.   MOLECULAR AND CELLULAR BIOLOGY

YAP and TAZ: a nexus for Hippo signaling and beyond

(2015) Carsten Gram Hansen et al.   TRENDS IN CELL BIOLOGY

Angiogenic sprouting is regulated by endothelial cell expression of Slug

(2014) K. M. Welch-Reardon et al.   JOURNAL OF CELL SCIENCE

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

(2014) Minna U. Kaikkonen et al.   NUCLEIC ACIDS RESEARCH

BMP4 is a novel transcriptional target and mediator of mammary cell migration downstream of the Hippo pathway component TAZ

(2013) Dulcie Lai et al.   CELLULAR SIGNALLING

EndMT contributes to the onset and progression of cerebral cavernous malformations

(2013) Luigi Maddaluno et al.   NATURE

Activin-Like Kinase 2 Functions in Peri-implantation Uterine Signaling in Mice and Humans

(2013) Caterina Clementi et al.   PLoS Genetics

TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin

(2012) Nuo Yang et al.   CELL CYCLE

BMP signaling in vascular diseases

(2012) Jie Cai et al.   FEBS LETTERS

Gremlin-1 Induces BMP-Independent Tumor Cell Proliferation, Migration, and Invasion

(2012) Minsoo Kim et al.   PLoS One

The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation

(2011) Andrew C. Newman et al.   MOLECULAR BIOLOGY OF THE CELL

Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

(2011) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

(2011) T. Heallen et al.   SCIENCE

Bone Morphogenetic Protein-2-Induced Signaling and Osteogenesis Is Regulated by Cell Shape, RhoA/ROCK, and Cytoskeletal Tension

(2011) Yang-Kao Wang et al.   STEM CELLS AND DEVELOPMENT

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

(2010) S. Rey et al.   CARDIOVASCULAR RESEARCH

Neogenin, a Receptor for Bone Morphogenetic Proteins

(2010) Meiko Hagihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hippo signaling at a glance

(2010) Bin Zhao et al.   JOURNAL OF CELL SCIENCE

Heat Shock Protein 70 Enhances Vascular Bone Morphogenetic Protein-4 Signaling by Binding Matrix Gla Protein

(2009) Yucheng Yao et al.   CIRCULATION RESEARCH

Bone morphogenetic protein receptors and signal transduction

(2009) K. Miyazono et al.   JOURNAL OF BIOCHEMISTRY

TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

(2009) Heng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt–β-catenin and Wnt–RhoA–Rac1 pathways

(2009) Vinicio A. de Jesus Perez et al.   JOURNAL OF CELL BIOLOGY

The VEGF-induced transcriptional response comprises gene clusters at the crossroad of angiogenesis and inflammation

(2009) Bernhard Schweighofer et al.   THROMBOSIS AND HAEMOSTASIS

Vascular permeability, vascular hyperpermeability and angiogenesis

(2008) Janice A. Nagy et al.   ANGIOGENESIS

Regulation of Vascular Endothelial Growth Factor D by Orphan Receptors Hepatocyte Nuclear Factor-4  and Chicken Ovalbumin Upstream Promoter Transcription Factors 1 and 2

(2008) G. Schafer et al.   CANCER RESEARCH

SM22 -targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis

(2008) N. El-Bizri et al.   DEVELOPMENT