IRE1 Endoribonuclease Activity Modulates Hypoxic HIF-1α Signaling in Human Endothelial Cells
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
IRE1 Endoribonuclease Activity Modulates Hypoxic HIF-1α Signaling in Human Endothelial Cells
Authors
Keywords
-
Journal
Biomolecules
Volume 10, Issue 6, Pages 895
Publisher
MDPI AG
Online
2020-06-16
DOI
10.3390/biom10060895
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia
- (2020) Sylwia Bartoszewska et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum
- (2019) G. Elif Karagöz et al. Cold Spring Harbor Perspectives in Biology
- Glucose-Regulated Protein 78 Signaling Regulates Hypoxia-Induced Epithelial–Mesenchymal Transition in A549 Cells
- (2019) Ling-Ling Sun et al. Frontiers in Oncology
- Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1
- (2019) Hatem Maamoun et al. Frontiers in Physiology
- Primary endothelial–specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia
- (2019) Rafal Bartoszewski et al. FASEB JOURNAL
- miR-34c-5p modulates X-box–binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response
- (2019) Sylwia Bartoszewska et al. FASEB JOURNAL
- Hypoxic ER stress suppresses β-catenin expression and promotes cooperation between the transcription factors XBP1 and HIF1α for cell survival
- (2019) Zhixiong Xia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome‐wide mRNA profiling identifies RCAN1 and GADD45A as regulators of the transitional switch from survival to apoptosis during ER stress
- (2019) Rafal Bartoszewski et al. FEBS Journal
- The Unfolded Protein Response and Cell Fate Control
- (2018) Claudio Hetz et al. MOLECULAR CELL
- Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF1α/VEGFA axis in breast cancer angiogenesis
- (2018) Huichun Liang et al. ONCOGENE
- Abstract 2042: Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine-tune the HIF1α/VEGFA axis in breast cancer angiogenesis
- (2018) Huichun Liang et al. CANCER RESEARCH
- The endoplasmic reticulum (ER) chaperone BiP is a master regulator of ER functions: Getting by with a little help from ERdj friends
- (2018) Kristine Faye R. Pobre et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HIF-1α triggers ER stress and CHOP-mediated apoptosis in alveolar epithelial cells, a key event in pulmonary fibrosis
- (2018) Eva Delbrel et al. Scientific Reports
- miRNA networks modulate human endothelial cell adaptation to cyclic hypoxia
- (2018) Kinga Kochan-Jamrozy et al. CELLULAR SIGNALLING
- miR-200b downregulates Kruppel Like Factor 2 (KLF2) during acute hypoxia in human endothelial cells
- (2017) Rafal Bartoszewski et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Regulation of tumor-stroma interactions by the unfolded protein response
- (2017) Joanna Obacz et al. FEBS Journal
- Anastasis and the ER stress response: Solving the paradox of the unfolded protein response in cancer
- (2017) Rafael Vincent M. Manalo MEDICAL HYPOTHESES
- IRE1α/XBP1s branch of UPR links HIF1α activation to mediate ANGII-dependent endothelial dysfunction under particulate matter (PM) 2.5 exposure
- (2017) Xiuduan Xu et al. Scientific Reports
- Codon bias and the folding dynamics of the cystic fibrosis transmembrane conductance regulator
- (2016) Rafal Bartoszewski et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells
- (2016) Mohammed Bensellam et al. DIABETOLOGIA
- Cysteine Sulfenylation Directs IRE-1 to Activate the SKN-1/Nrf2 Antioxidant Response
- (2016) John M. Hourihan et al. MOLECULAR CELL
- miR-429 regulates the transition between Hypoxia-Inducible Factor (HIF)1A and HIF3A expression in human endothelial cells
- (2016) Anna Janaszak-Jasiecka et al. Scientific Reports
- ER Stress and Angiogenesis
- (2015) François Binet et al. Cell Metabolism
- SalA Attenuates Hypoxia-Induced Endothelial Endoplasmic Reticulum Stress and Apoptosis via Down-Regulation of VLDL Receptor Expression
- (2015) Ping Xie et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop
- (2015) Sylwia Bartoszewska et al. FASEB JOURNAL
- Acute hypoxia produces a superoxide burst in cells
- (2014) Pablo Hernansanz-Agustín et al. FREE RADICAL BIOLOGY AND MEDICINE
- XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway
- (2014) Xi Chen et al. NATURE
- Reference Genes for Expression Studies in Hypoxia and Hyperglycemia Models in Human Umbilical Vein Endothelial Cells
- (2014) Sherin Bakhashab et al. G3-Genes Genomes Genetics
- Endoplasmic Reticulum (ER) Stress and Hypoxia Response Pathways Interact to Potentiate Hypoxia-inducible Factor 1 (HIF-1) Transcriptional Activity on Targets Like Vascular Endothelial Growth Factor (VEGF)
- (2013) Ethel R. Pereira et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IRE1: ER stress sensor and cell fate executor
- (2013) Yani Chen et al. TRENDS IN CELL BIOLOGY
- The Unfolded Protein Response Induces the Angiogenic Switch in Human Tumor Cells through the PERK/ATF4 Pathway
- (2012) Y. Wang et al. CANCER RESEARCH
- CHOP is a multifunctional transcription factor in the ER stress response
- (2012) H. Nishitoh JOURNAL OF BIOCHEMISTRY
- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
- (2012) Claudio Hetz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
- (2012) B. C. S. Cross et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Unfolded Protein Response (UPR)-activated Transcription Factor X-box-binding Protein 1 (XBP1) Induces MicroRNA-346 Expression That Targets the Human Antigen Peptide Transporter 1 (TAP1) mRNA and Governs Immune Regulatory Genes
- (2011) Rafal Bartoszewski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Oxidized Phospholipids Regulate Expression of ATF4 and VEGF in Endothelial Cells via NRF2-Dependent Mechanism: Novel Point of Convergence Between Electrophilic and Unfolded Protein Stress Pathways
- (2010) Taras Afonyushkin et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Transcriptional Regulation of VEGF-A by the Unfolded Protein Response Pathway
- (2010) Rajarshi Ghosh et al. PLoS One
- Transcriptional and Post-Transcriptional Regulation of Proangiogenic Factors by the Unfolded Protein Response
- (2010) Ethel R. Pereira et al. PLoS One
- IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates
- (2009) Dan Han et al. CELL
- The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
- (2009) Kasper M.A. Rouschop et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3
- (2009) Hilda Mujcic et al. RADIOTHERAPY AND ONCOLOGY
- Endoplasmic reticulum stress response in murine kidney exposed to acute hypobaric hypoxia
- (2008) Jayashree Karar et al. FEBS LETTERS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started