IRE1α/XBP1s branch of UPR links HIF1α activation to mediate ANGII-dependent endothelial dysfunction under particulate matter (PM) 2.5 exposure

Curcumin inhibits angiotensin II-induced inflammation and proliferation of rat vascular smooth muscle cells by elevating PPAR-γ activity and reducing oxidative stress

(2017) Hai-Yu Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Targeting IRE1 with small molecules counteracts progression of atherosclerosis

(2017) Ozlem Tufanli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deregulation of XBP1 expression contributes to myocardial vascular endothelial growth factor-A expression and angiogenesis during cardiac hypertrophyin vivo

(2016) Quanlu Duan et al.   AGING CELL

TP53-dependent autophagy links the ATR-CHEK1 axis activation to proinflammatory VEGFA production in human bronchial epithelial cells exposed to fine particulate matter (PM2.5)

(2016) Xiuduan Xu et al.   Autophagy

Environmental stressors and cardio-metabolic disease: part II–mechanistic insights

(2016) Thomas Münzel et al.   EUROPEAN HEART JOURNAL

Hypertension: Renin-Angiotensin-Aldosterone System Alterations

(2015) L. te Riet et al.   CIRCULATION RESEARCH

Involvement of the IRE1α-XBP1 Pathway and XBP1s-Dependent Transcriptional Reprogramming in Metabolic Diseases

(2015) Rong Wu et al.   DNA AND CELL BIOLOGY

Novel Mechanism of Blood Pressure Regulation By Forkhead Box Class O1–Mediated Transcriptional Control of Hepatic Angiotensinogen

(2014) Yajuan Qi et al.   HYPERTENSION

Gene Trapping Uncovers Sex-Specific Mechanisms for Upstream Stimulatory Factors 1 and 2 in Angiotensinogen Expression

(2012) Sungmi Park et al.   HYPERTENSION

Endothelial dysfunction as a cellular mechanism for vascular failure

(2011) Tetsuaki Hirase et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Particulate Matter Air Pollution and Cardiovascular Disease

(2010) Robert D. Brook et al.   CIRCULATION

A nuclear receptor, hepatocyte nuclear factor 4, differently contributes to the human and mouse angiotensinogen promoter activities

(2010) Takayuki Oishi et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase

(2009) Zhekang Ying et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vehicular Emissions Induce Vascular MMP-9 Expression and Activity Associated With Endothelin-1–Mediated Pathways

(2009) Amie K. Lund et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Synergistic co-operation of signal transducer and activator of transcription 5B with activator protein 1 in angiotensin II-induced angiotensinogen gene activation in vascular smooth muscle cells

(2009) Mei Han et al.   FEBS Journal

Air Pollution Exposure Potentiates Hypertension Through Reactive Oxygen Species-Mediated Activation of Rho/ROCK

(2008) Qinghua Sun et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Diesel Exhaust Inhalation Elicits Acute Vasoconstriction in Vivo

(2008) Alon Peretz et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Exposure to ultrafine carbon particles at levels below detectable pulmonary inflammation affects cardiovascular performance in spontaneously hypertensive rats

(2008) Swapna Upadhyay et al.   Particle and Fibre Toxicology