Vitamin D3 Ameliorates DNA Damage Caused by Developmental Exposure to Endocrine Disruptors in the Uterine Myometrial Stem Cells of Eker Rats

Vitamin D supplementation alters the expression of genes associated with hypertension and did not induce DNA damage in rats

(2019) Carla Da Silva Machado et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

MRN (MRE11-RAD50-NBS1) Complex in Human Cancer and Prognostic Implications in Colorectal Cancer

(2019) Yiling Situ et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Non-enzymatic roles of human RAD51 at stalled replication forks

(2019) Jennifer M. Mason et al.   Nature Communications

ATM-Mutated Pancreatic Cancer

(2019) Candice Martino et al.   PANCREAS

miR‐29 contributes to normal endothelial function and can restore it in cardiometabolic disorders

(2018) Michael E Widlansky et al.   EMBO Molecular Medicine

1,25-Dihydroxy vitamin D prevents tumorigenesis by inhibiting oxidative stress and inducing tumor cellular senescence in mice

(2018) Lulu Chen et al.   INTERNATIONAL JOURNAL OF CANCER

A Preliminary Study: Human Fibroid Stro-1+/CD44+ Stem Cells Isolated From Uterine Fibroids Demonstrate Decreased DNA Repair and Genomic Integrity Compared to Adjacent Myometrial Stro-1+/CD44+ Cells

(2018) Lauren E. Prusinski Fernung et al.   Reproductive Sciences

Breast cancer risk associated with genes encoding DNA repair MRN complex: a study from Punjab, Pakistan

(2018) Rabbia Tariq Khan et al.   Breast Cancer

Camptothecin induces G2/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen species

(2018) Rajapaksha Gedara Prasad Tharanga Jayaso et al.   Oncotarget

Antiproliferative Activity of Non-Calcemic Vitamin D Analogs on Human Melanoma Lines in Relation to VDR and PDIA3 Receptors

(2018) Tomasz Wasiewicz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors

(2018) Marialaura Petroni et al.   Cell Death & Disease

Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment

(2018) Mohamed Ali et al.   ACTA PHARMACOLOGICA SINICA

1,25 Dihydroxyvitamin D3 Enhances the Antifibroid Effects of Ulipristal Acetate in Human Uterine Fibroids

(2018) Mohamed Ali et al.   Reproductive Sciences

BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment

(2018) Giuseppina D’Alessandro et al.   Nature Communications

Emergence of uterine fibroid driver mutations in perturbed myometrial stem cells: the role ofhypovitaminosis D

(2017) H. Elkafas et al.   FERTILITY AND STERILITY

1α,25-dihydroxyvitamin D inhibits de novo fatty acid synthesis and lipid accumulation in metastatic breast cancer cells through down-regulation of pyruvate carboxylase

(2017) Tomasz Wilmanski et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Recent Advances in Uterine Fibroid Etiology

(2017) Michelle McWilliams et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Origin of Uterine Fibroids: Conversion of Myometrial Stem Cells to Tumor-Initiating Cells

(2017) Hoda Elkafas et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication

(2016) Stephen K. Godin et al.   Biochemistry and Cell Biology

Role of Stro1+/CD44+ stem cells in myometrial physiology and uterine remodeling during pregnancy†

(2016) Aymara Mas et al.   BIOLOGY OF REPRODUCTION

The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids1

(2016) Qiwei Yang et al.   BIOLOGY OF REPRODUCTION

The Roles of Vitamin D and Its Analogs in Inflammatory Diseases

(2016) Zongtao Lin et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Vitamin D3 Inhibits Wnt/β-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid Cells

(2016) Ayman Al-Hendy et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Vitamin D3 deficiency increases DNA damage and the oxidative burst of neutrophils in a hypertensive rat model

(2016) Carla da Silva Machado et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Vitamin D/vitamin D receptor axis regulates DNA repair during oncogene-induced senescence

(2016) S Graziano et al.   ONCOGENE

Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis

(2016) Aymara Mas et al.   STEM CELLS

Early Life Adverse Environmental Exposures Increase the Risk of Uterine Fibroid Development: Role of Epigenetic Regulation

(2016) Qiwei Yang et al.   Frontiers in Pharmacology

Uterine fibroids

(2016) Elizabeth A. Stewart et al.   Nature Reviews Disease Primers

Role of vitamin D in uterine fibroid biology

(2015) Soumia Brakta et al.   FERTILITY AND STERILITY

Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin

(2015) Wendy J. Cannan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1

(2015) Amanda W. Kijas et al.   NUCLEIC ACIDS RESEARCH

Proceedings from the Third National Institutes of Health International Congress on Advances in Uterine Leiomyoma Research: comprehensive review, conference summary and future recommendations

(2014) James H. Segars et al.   HUMAN REPRODUCTION UPDATE

Paricalcitol, a Vitamin D Receptor Activator, Inhibits Tumor Formation in a Murine Model of Uterine Fibroids

(2014) Sunil K. Halder et al.   Reproductive Sciences

Estrogen Signaling and the DNA Damage Response in Hormone Dependent Breast Cancers

(2014) C. Elizabeth Caldon   Frontiers in Oncology

1,25-Dihydroxyvitamin D3 Reduces Extracellular Matrix-Associated Protein Expression in Human Uterine Fibroid Cells1

(2013) Sunil K. Halder et al.   BIOLOGY OF REPRODUCTION

Exposure to diethylstilbestrol during sensitive life stages: A legacy of heritable health effects

(2013) Casey E. Reed et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Diethylstilbestrol (DES)-Stimulated Hormonal Toxicity is Mediated by ERα Alteration of Target Gene Methylation Patterns and Epigenetic Modifiers (DNMT3A, MBD2, and HDAC2) in the Mouse Seminal Vesicle

(2013) Yin Li et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Novel roles of 1α,25(OH)2D3 on DNA repair provide new strategies for breast cancer treatment

(2013) Susana Gonzalo   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Uterine Fibroids

(2013) Serdar E. Bulun   NEW ENGLAND JOURNAL OF MEDICINE

DNA Damage Sensing by the ATM and ATR Kinases

(2013) A. Marechal et al.   Cold Spring Harbor Perspectives in Biology

Identification and characterization of the human leiomyoma side population as putative tumor-initiating cells

(2012) Aymara Mas et al.   FERTILITY AND STERILITY

BRCA1-dependent Chk1 phosphorylation triggers partial chromatin disassociation of phosphorylated Chk1 and facilitates S-phase cell cycle arrest

(2012) Ronit I. Yarden et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of Stem Cells in Human Uterine Leiomyoma Growth

(2012) Masanori Ono et al.   PLoS One

The estimated annual cost of uterine leiomyomata in the United States

(2011) Eden R. Cardozo et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The anti-cancer and anti-inflammatory actions of 1,25(OH)2D3

(2011) E. Vanoirbeek et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

A Positive Feedback Signaling Loop between ATM and the Vitamin D Receptor Is Critical for Cancer Chemoprevention by Vitamin D

(2011) H.-J. Ting et al.   CANCER RESEARCH

Early-Life Exposures and Early-Onset Uterine Leiomyomata in Black Women in the Sister Study

(2011) Aimee A. D’Aloisio et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Association of Intrauterine and Early-Life Exposures With Age at Menopause in the Sister Study

(2010) A. Z. Steiner et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase

(2010) Chakradhari Sharan et al.   FERTILITY AND STERILITY

Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement

(2009) Evanthia Diamanti-Kandarakis et al.   ENDOCRINE REVIEWS

Association of Intrauterine and Early-Life Exposures with Diagnosis of Uterine Leiomyomata by 35 Years of Age in the Sister Study

(2009) Aimee A. D’Aloisio et al.   ENVIRONMENTAL HEALTH PERSPECTIVES