Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin

DNA end resection is needed for the repair of complex lesions in G1-phase human cells

(2014) Nicole B Averbeck et al.   CELL CYCLE

The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability

(2014) Stephan Hamperl et al.   DNA REPAIR

Base excision repair: A critical player in many games

(2014) Susan S. Wallace   DNA REPAIR

Chromatin structure and radiation-induced DNA damage: From structural biology to radiobiology

(2014) Christophe Lavelle et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Nucleosomes Suppress the Formation of Double-strand DNA Breaks during Attempted Base Excision Repair of Clustered Oxidative Damages

(2014) Wendy J. Cannan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Point/Counterpoint: Low-dose radiation is beneficial, not harmful

(2014) Mohan Doss et al.   MEDICAL PHYSICS

An impenetrable barrier to ultrarelativistic electrons in the Van Allen radiation belts

(2014) D. N. Baker et al.   NATURE

An update on PARP inhibitors—moving to the adjuvant setting

(2014) Amir Sonnenblick et al.   Nature Reviews Clinical Oncology

Recombination and Replication

(2014) A. H. Syeda et al.   Cold Spring Harbor Perspectives in Biology

Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair

(2014) A. Mehta et al.   Cold Spring Harbor Perspectives in Biology

Knock-In Reporter Mice Demonstrate that DNA Repair by Non-homologous End Joining Declines with Age

(2014) Amita Vaidya et al.   PLoS Genetics

Systematic Review: Charged-Particle Radiation Therapy for Cancer

(2013) Teruhiko Terasawa   ANNALS OF INTERNAL MEDICINE

Initiation of Meiotic Recombination: How and Where? Conservation and Specificities Among Eukaryotes

(2013) Bernard de Massy   Annual Review of Genetics

Break-induced replication: functions and molecular mechanism

(2013) Anna Malkova et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The complexity of DNA double strand breaks is a critical factor enhancing end-resection

(2013) Hirohiko Yajima et al.   DNA REPAIR

Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomes

(2013) Robyn L. Maher et al.   DNA REPAIR

The Structural Location of DNA Lesions in Nucleosome Core Particles Determines Accessibility by Base Excision Repair Enzymes

(2013) Yesenia Rodriguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

(2013) L. N. Truong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Base Excision Repair

(2013) H. E. Krokan et al.   Cold Spring Harbor Perspectives in Biology

The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability

(2013) Lamia Wahba et al.   eLife

Mutations Arising During Repair of Chromosome Breaks

(2012) Anna Malkova et al.   Annual Review of Genetics

Enzymatic Excision of Uracil Residues in Nucleosomes Depends on the Local DNA Structure and Dynamics

(2012) Yu Ye et al.   BIOCHEMISTRY

Chromothripsis and Human Disease: Piecing Together the Shattering Process

(2012) Christopher A. Maher et al.   CELL

Systematic Review and Meta-analysis of Circulatory Disease from Exposure to Low-Level Ionizing Radiation and Estimates of Potential Population Mortality Risks

(2012) Mark P. Little et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Chromatin organization — The 30nm fiber

(2012) Sergei A. Grigoryev et al.   EXPERIMENTAL CELL RESEARCH

Mating-Type Genes and MAT Switching in Saccharomyces cerevisiae

(2012) J. E. Haber   GENETICS

Rules of engagement for base excision repair in chromatin

(2012) Ian D. Odell et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic response

(2012) Ho Lam Tang et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of DSB Processing Requires Phosphorylation of CtIP by ATR

(2012) Shaun E. Peterson et al.   MOLECULAR CELL

Ionizing radiation biomarkers for potential use in epidemiological studies

(2012) Eileen Pernot et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography

(2012) Larry H. Thompson   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

DNA breaks and chromosome pulverization from errors in mitosis

(2012) Karen Crasta et al.   NATURE

The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage

(2012) Pamela Reynolds et al.   NUCLEIC ACIDS RESEARCH

Beyond Repair Foci: DNA Double-Strand Break Repair in Euchromatic and Heterochromatic Compartments Analyzed by Transmission Electron Microscopy

(2012) Yvonne Lorat et al.   PLoS One

Chromosomes without a 30-nm chromatin fiber

(2012) Yasumasa Joti et al.   Nucleus

Cancer Genomes Evolve by Pulverizing Single Chromosomes

(2011) Matthew Meyerson et al.   CELL

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

When catastrophe strikes a cell

(2011) Jose M. C. Tubio et al.   NATURE

Base excision repair of 8-oxoG in dinucleosomes

(2011) Hervé Menoni et al.   NUCLEIC ACIDS RESEARCH

The consequences of structural genomic alterations in humans: Genomic Disorders, genomic instability and cancer

(2011) Rita Colnaghi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Complex regulation and function of activation-induced cytidine deaminase

(2011) Janet Stavnezer   TRENDS IN IMMUNOLOGY

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

DNA damage signaling in response to double-strand breaks during mitosis

(2010) Simona Giunta et al.   JOURNAL OF CELL BIOLOGY

Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation

(2010) Aroumougame Asaithamby et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Delayed repair of radiation induced clustered DNA damage: Friend or foe?

(2010) Laura J. Eccles et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Clustered DNA lesion repair in eukaryotes: Relevance to mutagenesis and cell survival

(2010) Evelyne Sage et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Higher-order chromatin structure in DSB induction, repair and misrepair

(2010) Martin Falk et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

DNA interstrand cross-links induced by ionizing radiation: An unsung lesion

(2010) Marie-Eve Dextraze et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae

(2010) T. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse Embryonic Stem Cells, but Not Somatic Cells, Predominantly Use Homologous Recombination to Repair Double-Strand DNA Breaks

(2010) Elisia D. Tichy et al.   STEM CELLS AND DEVELOPMENT

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

(2010) Marcel A. T. M. van Vugt et al.   PLOS BIOLOGY

Teraelectronvolt Astronomy

(2009) J.A. Hinton et al.   Annual Review of Astronomy and Astrophysics

DNA Repair in Mammalian Cells

(2009) A. B. Robertson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tyrosyl-DNA phosphodiesterase and the repair of 3′-phosphoglycolate-terminated DNA double-strand breaks

(2009) Tong Zhou et al.   DNA REPAIR

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle

(2009) Maximina H. Yun et al.   NATURE

Single-Strand Annealing, Conservative Homologous Recombination, Nonhomologous DNA End Joining, and the Cell Cycle-Dependent Repair of DNA Double-Strand Breaks Induced by Sparsely or Densely Ionizing Radiation

(2009) Marlis Frankenberg-Schwager et al.   RADIATION RESEARCH

Nucleases and helicases take center stage in homologous recombination

(2009) Eleni P. Mimitou et al.   TRENDS IN BIOCHEMICAL SCIENCES

Developmental genome rearrangements in ciliates: a natural genomic subtraction mediated by non-coding transcripts

(2009) Sandra Duharcourt et al.   TRENDS IN GENETICS

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Chromatin structure influences the sensitivity of DNA to γ-radiation

(2008) Martin Falk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

(2008) Muralidhar L Hegde et al.   CELL RESEARCH

CDK targets Sae2 to control DNA-end resection and homologous recombination

(2008) Pablo Huertas et al.   NATURE