A Preliminary Study: Human Fibroid Stro-1+/CD44+ Stem Cells Isolated From Uterine Fibroids Demonstrate Decreased DNA Repair and Genomic Integrity Compared to Adjacent Myometrial Stro-1+/CD44+ Cells

Highly heterogeneous genomic landscape of uterine leiomyomas by whole exome sequencing and genome-wide arrays

(2017) Svetlana A. Yatsenko et al.   FERTILITY AND STERILITY

The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids1

(2016) Qiwei Yang et al.   BIOLOGY OF REPRODUCTION

Decreased DNA repair gene XRCC1 expression is associated with radiotherapy-induced acute side effects in breast cancer patients

(2016) Bahadir Batar et al.   GENE

Emerging Non-Canonical Functions and Regulation by p53: p53 and Stemness

(2016) David Olivos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tissue-specific mutation accumulation in human adult stem cells during life

(2016) Francis Blokzijl et al.   NATURE

Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes

(2016) Ray Kreienkamp et al.   Oncotarget

Estrogen Receptor Expression Is Associated with DNA Repair Capacity in Breast Cancer

(2016) Jaime Matta et al.   PLoS One

Differences in DNA Repair Capacity, Cell Death and Transcriptional Response after Irradiation between a Radiosensitive and a Radioresistant Cell Line

(2016) Mireia Borràs-Fresneda et al.   Scientific Reports

Endocrinology of uterine fibroids

(2015) Molly B. Moravek et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Stro-1/CD44 as putative human myometrial and fibroid stem cell markers

(2015) Aymara Mas et al.   FERTILITY AND STERILITY

DNA Repair—A Double-Edged Sword in the Genomic Stability of Cancer Cells—The Case of Chronic Myeloid Leukemia

(2015) Elzbieta Pawlowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors

(2015) Andrea J Hartlerode et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

(2015) C. Tomasetti et al.   SCIENCE

Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors

(2015) Andrea J Hartlerode et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids

(2014) Sunil K. Halder et al.   MOLECULAR GENETICS AND GENOMICS

Impact of genomic damage and ageing on stem cell function

(2014) Axel Behrens et al.   NATURE CELL BIOLOGY

Mechanisms underlying mutational signatures in human cancers

(2014) Thomas Helleday et al.   NATURE REVIEWS GENETICS

Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches

(2014) Felix Dietlein et al.   TRENDS IN GENETICS

CHK2 kinase in the DNA damage response and beyond

(2014) L. Zannini et al.   Journal of Molecular Cell Biology

Uterine Fibroids

(2013) Serdar E. Bulun   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of Uterine Leiomyomas by Whole-Genome Sequencing

(2013) Miika Mehine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Review: Human uterine stem/progenitor cells: Implications for uterine physiology and pathology

(2013) T. Maruyama et al.   PLACENTA

Triple Negative Breast Cancers Have a Reduced Expression of DNA Repair Genes

(2013) Enilze Ribeiro et al.   PLoS One

Use of the γ-H2AX Assay to Investigate DNA Repair Dynamics Following Multiple Radiation Exposures

(2013) Luca G. Mariotti et al.   PLoS One

Differences in Phosphorylated Histone H2AX Foci Formation and Removal of Cells Exposed to Low and High Linear Energy Transfer Radiation

(2012) Thomas Ernst Schmid et al.   CURRENT GENOMICS

Identification and characterization of the human leiomyoma side population as putative tumor-initiating cells

(2012) Aymara Mas et al.   FERTILITY AND STERILITY

MED12 mutations in uterine fibroids-their relationship to cytogenetic subgroups

(2012) Dominique Nadine Markowski et al.   INTERNATIONAL JOURNAL OF CANCER

Defective DNA repair systems and the development of breast and prostate cancer

(2012) YASUKO KITAGISHI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

DNA Damage Repair Pathways in Cancer Stem Cells

(2012) M. Maugeri-Sacca et al.   MOLECULAR CANCER THERAPEUTICS

Role of Stem Cells in Human Uterine Leiomyoma Growth

(2012) Masanori Ono et al.   PLoS One

DNA-Damage Response in Tissue-Specific and Cancer Stem Cells

(2011) Cedric Blanpain et al.   Cell Stem Cell

MED12, the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas

(2011) N. Makinen et al.   SCIENCE

Radiation induced DNA DSBs: Contribution from stalled replication forks?

(2010) Jane V. Harper et al.   DNA REPAIR

H2AX: functional roles and potential applications

(2009) Jennifer S. Dickey et al.   CHROMOSOMA

Uterine Leiomyomas Exhibit Fewer Stem/Progenitor Cell Characteristics When Compared With Corresponding Normal Myometrium

(2009) Henry L. Chang et al.   Reproductive Sciences

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BRCA1 regulates human mammary stem/progenitor cell fate

(2008) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA