Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication

Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans

(2016) T. Brooke McClendon et al.   GENETICS

Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans

(2016) T. Brooke McClendon et al.   GENETICS

Association between the XRCC3 Thr241Met Polymorphism and Risk of Colorectal Cancer: a Meta Analysis of 5,193 Cases and 6,645 Controls

(2015) Abolfazl Namazi et al.   Asian Pacific Journal of Cancer Prevention

Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination

(2015) Martin R.G. Taylor et al.   CELL

DNA Sequence Alignment by Microhomology Sampling during Homologous Recombination

(2015) Zhi Qi et al.   CELL

The DNA Damage Response and Checkpoint Adaptation in Saccharomyces cerevisiae: Distinct Roles for the Replication Protein A2 (Rfa2) N-Terminus

(2015) P. L. Ghospurkar et al.   GENETICS

Evolutionary and Functional Analysis of the Invariant SWIM Domain in the Conserved Shu2/SWS1 Protein Family from Saccharomyces cerevisiae to Homo sapiens

(2015) Stephen K. Godin et al.   GENETICS

DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous Recombination

(2015) Petr Cejka   JOURNAL OF BIOLOGICAL CHEMISTRY

Top3-Rmi1 Dissolve Rad51-Mediated D Loops by a Topoisomerase-Based Mechanism

(2015) Clare L. Fasching et al.   MOLECULAR CELL

A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination

(2015) Anderson T. Wang et al.   MOLECULAR CELL

Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart

(2015) Kumar Somyajit et al.   NUCLEIC ACIDS RESEARCH

A novel role for non-ubiquitinated FANCD2 in response to hydroxyurea-induced DNA damage

(2015) X Chen et al.   ONCOGENE

Single Nucleotide Polymorphisms (SNPs) of RAD51-G172T and XRCC2-41657C/T Homologous Recombination Repair Genes and the Risk of Triple- Negative Breast Cancer in Polish Women

(2015) Magdalena M. Michalska et al.   PATHOLOGY & ONCOLOGY RESEARCH

Base triplet stepping by the Rad51/RecA family of recombinases

(2015) J. Y. Lee et al.   SCIENCE

Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins

(2015) Rohit Prakash et al.   Cold Spring Harbor Perspectives in Biology

FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51

(2015) Wai Kit Chu et al.   Nature Communications

A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51

(2015) Najim Ameziane et al.   Nature Communications

Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52

(2015) William A. Gaines et al.   Nature Communications

Evolutionary and Functional Analysis of the Invariant SWIM Domain in the Conserved Shu2/SWS1 Protein Family from Saccharomyces cerevisiae to Homo sapiens

(2015) Stephen K. Godin et al.   GENETICS

RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer families

(2015) Liisa M Pelttari et al.   SpringerPlus

PALB2: The hub of a network of tumor suppressors involved in DNA damage responses

(2014) Jung-Young Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families

(2014) Ana Blanco et al.   BREAST CANCER RESEARCH AND TREATMENT

Enhanced non-homologous end joining contributes toward synthetic lethality of pathological RAD51C mutants with poly (ADP-ribose) polymerase

(2014) Kumar Somyajit et al.   CARCINOGENESIS

RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA

(2014) N. Manfrini et al.   EMBO REPORTS

BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells

(2014) Marcel Reuter et al.   JOURNAL OF CELL BIOLOGY

Visualization of recombination-mediated damage bypass by template switching

(2014) Michele Giannattasio et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules

(2014) Bryan Gibb et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor

(2014) Taha Shahid et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization

(2013) Anand D Jeyasekharan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55–Rad57 to mediate error-free recombination

(2013) Stephen Godin et al.   NUCLEIC ACIDS RESEARCH

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

(2013) J-Y Park et al.   ONCOGENE

The Yeast Shu Complex Utilizes Homologous Recombination Machinery for Error-free Lesion Bypass via Physical Interaction with a Rad51 Paralogue

(2013) Xin Xu et al.   PLoS One

Combined optical and topographic imaging reveals different arrangements of human RAD54 with presynaptic and postsynaptic RAD51-DNA filaments

(2013) H. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells

(2013) Lorenzo Costantino et al.   SCIENCE

Break-Induced DNA Replication

(2013) R. P. Anand et al.   Cold Spring Harbor Perspectives in Biology

A new protein complex promoting the assembly of Rad51 filaments

(2013) Hiroyuki Sasanuma et al.   Nature Communications

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

(2012) Katharina Schlacher et al.   CANCER CELL

From yeast to mammals: Recent advances in genetic control of homologous recombination

(2012) Yoav Karpenshif et al.   DNA REPAIR

Structural and SAXS analysis of the budding yeast SHU-complex proteins

(2012) Zhun She et al.   FEBS LETTERS

Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families

(2012) Ana Osorio et al.   HUMAN MOLECULAR GENETICS

Structural Analysis of Shu Proteins Reveals a DNA Binding Role Essential for Resisting Damage

(2012) Yuyong Tao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exome sequencing reveals a novel Fanconi group defined by XRCC2 mutation: Figure 1

(2012) Hanan E Shamseldin et al.   JOURNAL OF MEDICAL GENETICS

Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway

(2012) J. Chun et al.   MOLECULAR AND CELLULAR BIOLOGY

A Novel Antirecombinase Gains PARIty

(2012) Hocine W. Mankouri et al.   MOLECULAR CELL

Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes

(2011) Erin K. Schwartz et al.   CHROMOSOMA

DNA end resection—Unraveling the tail

(2011) Eleni P. Mimitou et al.   DNA REPAIR

Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients

(2011) Ella R. Thompson et al.   HUMAN MUTATION

hSWS1·SWSAP1 Is an Evolutionarily Conserved Complex Required for Efficient Homologous Recombination Repair

(2011) Ting Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase

(2011) Kara A. Bernstein et al.   MOLECULAR BIOLOGY OF THE CELL

Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI

(2011) George-Lucian Moldovan et al.   MOLECULAR CELL

Rad51 paralogues Rad55–Rad57 balance the antirecombinase Srs2 in Rad51 filament formation

(2011) Jie Liu et al.   NATURE

The MRE11 complex: starting from the ends

(2011) Travis H. Stracker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RAD51C Germline Mutations in Breast and Ovarian Cancer Cases from High-Risk Families

(2011) Jessica Clague et al.   PLoS One

Regulation of Homologous Recombination in Eukaryotes

(2010) Wolf-Dietrich Heyer et al.   Annual Review of Genetics

The RecQ DNA Helicases in DNA Repair

(2010) Kara A. Bernstein et al.   Annual Review of Genetics

Mre11–Rad50–Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks

(2010) Gareth J. Williams et al.   DNA REPAIR

Making the best of the loose ends: Mre11/Rad50 complexes and Sae2 promote DNA double-strand break resection

(2010) Tanya T. Paull   DNA REPAIR

Ring-shaped Rad51 Paralog Protein Complexes Bind Holliday Junctions and Replication Forks as Visualized by Electron Microscopy

(2010) Sarah A. Compton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overlapping Mechanisms Promote Postsynaptic RAD-51 Filament Disassembly during Meiotic Double-Strand Break Repair

(2010) Jordan D. Ward et al.   MOLECULAR CELL

Purified human BRCA2 stimulates RAD51-mediated recombination

(2010) Ryan B. Jensen et al.   NATURE

Fanconi anemia and breast cancer susceptibility meet again

(2010) Ephrat Levy-Lahad   NATURE GENETICS

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

(2010) Alfons Meindl et al.   NATURE GENETICS

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA

(2010) Jie Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA

(2010) Tina Thorslund et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

(2010) Yoshitami Hashimoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Loss of Rad51c Leads to Embryonic Lethality and Modulation of Trp53-Dependent Tumorigenesis in Mice

(2009) S. G. Kuznetsov et al.   CANCER RESEARCH

At Loose Ends: Resecting a Double-Strand Break

(2009) Kara A. Bernstein et al.   CELL

The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51

(2009) Aura Carreira et al.   CELL

The yeast Shu complex couples error-free post-replication repair to homologous recombination

(2009) Lindsay G. Ball et al.   MOLECULAR MICROBIOLOGY

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

Homologous recombination in DNA repair and DNA damage tolerance

(2008) Xuan Li et al.   CELL RESEARCH

Functional Interactions Between Sae2 and the Mre11 Complex

(2008) H.-S. Kim et al.   GENETICS

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

(2008) Eleni P. Mimitou et al.   NATURE

CDK targets Sae2 to control DNA-end resection and homologous recombination

(2008) Pablo Huertas et al.   NATURE

Identification of Holliday junction resolvases from humans and yeast

(2008) Stephen C. Y. Ip et al.   NATURE