Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment

gamma-H2AX: Can it be established as a classical cancer prognostic factor?

(2017) Viktoria-Varvara Palla et al.   TUMOR BIOLOGY

DNA mismatch repair and the DNA damage response

(2016) Zhongdao Li et al.   DNA REPAIR

Vitamin D3 Inhibits Wnt/β-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid Cells

(2016) Ayman Al-Hendy et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Vitamin D3 deficiency increases DNA damage and the oxidative burst of neutrophils in a hypertensive rat model

(2016) Carla da Silva Machado et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Vitamin D/vitamin D receptor axis regulates DNA repair during oncogene-induced senescence

(2016) S Graziano et al.   ONCOGENE

Identification of Polycomb Group Protein EZH2-Mediated DNA Mismatch Repair Gene MSH2 in Human Uterine Fibroids

(2016) Qiwei Yang et al.   Reproductive Sciences

Uterine fibroids

(2016) Elizabeth A. Stewart et al.   Nature Reviews Disease Primers

Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3

(2016) H. Dorota Halicka et al.   Aging-US

Role of vitamin D in uterine fibroid biology

(2015) Soumia Brakta et al.   FERTILITY AND STERILITY

Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin

(2015) Wendy J. Cannan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

1,25-Dihydroxyvitamin D3 Regulates Expression of Sex Steroid Receptors in Human Uterine Fibroid Cells

(2015) Ayman Al-Hendy et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Med12 gain-of-function mutation causes leiomyomas and genomic instability

(2015) Priya Mittal et al.   JOURNAL OF CLINICAL INVESTIGATION

Homologous Recombination Repair Factors Rad51 and BRCA1 Are Necessary for Productive Replication of Human Papillomavirus 31

(2015) William H. Chappell et al.   JOURNAL OF VIROLOGY

Role of Vitamin D Metabolism and Activity on Carcinogenesis

(2015) Xiayu Wu et al.   ONCOLOGY RESEARCH

MED12 exon 2 mutations are common in uterine leiomyomas from South African patients

(2015) Netta Mäkinen et al.   Oncotarget

Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids

(2014) Sunil K. Halder et al.   MOLECULAR GENETICS AND GENOMICS

Tumour Suppressor Mechanisms in the Control of Chromosome Stability: Insights from BRCA2

(2014) Ashok R. Venkitaraman   MOLECULES AND CELLS

Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches

(2014) Felix Dietlein et al.   TRENDS IN GENETICS

Is homologous recombination really an error-free process?

(2014) Josée Guirouilh-Barbat et al.   Frontiers in Genetics

Estrogen Signaling and the DNA Damage Response in Hormone Dependent Breast Cancers

(2014) C. Elizabeth Caldon   Frontiers in Oncology

1,25-Dihydroxyvitamin D3 Reduces Extracellular Matrix-Associated Protein Expression in Human Uterine Fibroid Cells1

(2013) Sunil K. Halder et al.   BIOLOGY OF REPRODUCTION

Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells

(2013) S. K. Halder et al.   HUMAN REPRODUCTION

Novel roles of 1α,25(OH)2D3 on DNA repair provide new strategies for breast cancer treatment

(2013) Susana Gonzalo   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation

(2013) Liam D. Cassidy et al.   Molecular Oncology

γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies

(2013) Vanessa Valdiglesias et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Characterization of Uterine Leiomyomas by Whole-Genome Sequencing

(2013) Miika Mehine et al.   NEW ENGLAND JOURNAL OF MEDICINE

1,25-Dihydroxyvitamin D3 Treatment Shrinks Uterine Leiomyoma Tumors in the Eker Rat Model1

(2012) Sunil K. Halder et al.   BIOLOGY OF REPRODUCTION

Whole Exome Sequencing in a Random Sample of North American Women with Leiomyomas Identifies MED12 Mutations in Majority of Uterine Leiomyomas

(2012) Megan M. McGuire et al.   PLoS One

The estimated annual cost of uterine leiomyomata in the United States

(2011) Eden R. Cardozo et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Vitamin D and cancer: a review of molecular mechanisms

(2011) James C. Fleet et al.   BIOCHEMICAL JOURNAL

Réparation des cassures double-brin de l’ADN, un mécanisme peut en cacher un autre : la ligature d’extrémités non homologues alternative

(2011) E. Rass et al.   Cancer Radiotherapie

A Positive Feedback Signaling Loop between ATM and the Vitamin D Receptor Is Critical for Cancer Chemoprevention by Vitamin D

(2011) H.-J. Ting et al.   CANCER RESEARCH

1,25-Dihydroxyvitamin D3Reduces TGF-β3-Induced Fibrosis-Related Gene Expression in Human Uterine Leiomyoma Cells

(2011) Sunil K. Halder et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The MRE11 complex: starting from the ends

(2011) Travis H. Stracker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms

(2011) A. Carreira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mre11–Rad50–Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks

(2010) Gareth J. Williams et al.   DNA REPAIR

The Vitamin D Receptor: New Paradigms for the Regulation of Gene Expression by 1,25-Dihydroxyvitamin D3

(2010) J. Wesley Pike et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase

(2010) Chakradhari Sharan et al.   FERTILITY AND STERILITY