Lymph nodes—The neglected battlefield in tuberculosis

Prevention of tuberculosis in macaques after intravenous BCG immunization

(2020) Patricia A. Darrah et al.   NATURE

Enhanced Mycobacterial Antigen–Induced Pro-Inflammatory Cytokine Production in Lymph Node Tuberculosis

(2019) Gokul Raj Kathamuthu et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Immune Response to Mycobacterium tuberculosis: A Narrative Review

(2019) Maurizio de Martino et al.   Frontiers in Pediatrics

Disparate Tuberculosis Disease Development in Macaque Species Is Associated With Innate Immunity

(2019) Karin Dijkman et al.   Frontiers in Immunology

IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Mycobacterium tuberculosis Infection

(2019) Eileen A. Wong et al.   JOURNAL OF IMMUNOLOGY

Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine

(2018) Scott G Hansen et al.   NATURE MEDICINE

Mycobacterium tuberculosis Erdman infection of cynomolgus macaques of Chinese origin

(2018) Jing Zhang et al.   Journal of Thoracic Disease

Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques

(2018) Sharie Keanne C. Ganchua et al.   PLoS Pathogens

Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques

(2018) Anthony M. Cadena et al.   PLoS Pathogens

Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1–Expressing Immune Cells

(2017) Joshua T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis

(2017) Constance J. Martin et al.   mBio

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

(2017) Alexander G. White et al.   Jove-Journal of Visualized Experiments

A Drug-Free Zone—Lymph Nodes as a Safe Haven for HIV

(2016) Anna Licht et al.   Cell Host & Microbe

Persistent HIV-1 replication maintains the tissue reservoir during therapy

(2016) Ramon Lorenzo-Redondo et al.   NATURE

Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography

(2016) Hanif Esmail et al.   NATURE MEDICINE

Ultra low dose aerosol challenge with Mycobacterium tuberculosis leads to divergent outcomes in rhesus and cynomolgus macaques

(2016) Sally Sharpe et al.   TUBERCULOSIS

The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling

(2016) Rein M. G. J. Houben et al.   PLOS MEDICINE

PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis

(2016) Philana Ling Lin et al.   PLoS Pathogens

Immunology studies in non-human primate models of tuberculosis

(2015) JoAnne L. Flynn et al.   IMMUNOLOGICAL REVIEWS

Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis

(2015) Deepak Kaushal et al.   Nature Communications

Expression profiling of lymph nodes in tuberculosis patients reveal inflammatory milieu at site of infection

(2015) Abhijit Maji et al.   Scientific Reports

Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization

(2015) Hannah Priyadarshini Gideon et al.   PLoS Pathogens

Early Changes by 18Fluorodeoxyglucose Positron Emission Tomography Coregistered with Computed Tomography Predict Outcome after Mycobacterium tuberculosis Infection in Cynomolgus Macaques

(2014) M. T. Coleman et al.   INFECTION AND IMMUNITY

Latent Tuberculosis Infection: Myths, Models, and Molecular Mechanisms

(2014) N. K. Dutta et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

(2014) Courtney V. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis

(2014) M. T. Coleman et al.   Science Translational Medicine

Mycobacterium tuberculosis Erdman infection of rhesus macaques of Chinese origin

(2014) Jing Zhang et al.   TUBERCULOSIS

Modeling Tuberculosis in Nonhuman Primates

(2014) C. A. Scanga et al.   Cold Spring Harbor Perspectives in Medicine

The Immune Response in Tuberculosis

(2013) Anne O'Garra et al.   Annual Review of Immunology

Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens

(2013) Philana Ling Lin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials

(2013) Punam Mangtani et al.   CLINICAL INFECTIOUS DISEASES

Inoculation Dose of Mycobacterium tuberculosis Does Not Influence Priming of T Cell Responses in Lymph Nodes

(2013) A. J. Myers et al.   JOURNAL OF IMMUNOLOGY

Is tuberculosis a lymphatic disease with a pulmonary portal?

(2013) Marcel A Behr et al.   LANCET INFECTIOUS DISEASES

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

(2013) Philana Ling Lin et al.   NATURE MEDICINE

Lung dendritic cells facilitate extrapulmonary bacterial dissemination during pneumococcal pneumonia

(2013) Alva Rosendahl et al.   Frontiers in Cellular and Infection Microbiology

CD4 T Cell Depletion Exacerbates Acute Mycobacterium tuberculosis While Reactivation of Latent Infection Is Dependent on Severity of Tissue Depletion in Cynomolgus Macaques

(2012) Philana Ling Lin et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques

(2012) P. L. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis

(2012) Ying Waeckerle-Men et al.   VACCINE

Nodal tuberculosis revisited: a review

(2012) Uma Handa et al.   Journal of Infection in Developing Countries

Current Diagnosis and Management of Peripheral Tuberculous Lymphadenitis

(2011) J.-M. Fontanilla et al.   CLINICAL INFECTIOUS DISEASES

Unique Type I Interferon Responses Determine the Functional Fate of Migratory Lung Dendritic Cells during Influenza Virus Infection

(2011) Bruno Moltedo et al.   PLoS Pathogens

Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load

(2010) Collin R. Diedrich et al.   PLoS One

Compartmentalization of Immune Responses in Human Tuberculosis

(2009) Sayma Rahman et al.   AMERICAN JOURNAL OF PATHOLOGY

Epidemiology of Extrapulmonary Tuberculosis in the United States, 1993–2006

(2009) Heather M. Peto et al.   CLINICAL INFECTIOUS DISEASES

Dynamics of T Cell, Antigen-Presenting Cell, and Pathogen Interactions during Recall Responses in the Lymph Node

(2009) Tatyana Chtanova et al.   IMMUNITY

Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model

(2009) P. L. Lin et al.   INFECTION AND IMMUNITY

Respiratory Dendritic Cell Subsets Differ in Their Capacity to Support the Induction of Virus-Specific Cytotoxic CD8+ T Cell Responses

(2009) Taeg S. Kim et al.   PLoS One

Extrapulmonary Dissemination of Mycobacterium bovis but Not Mycobacterium tuberculosis in a Bronchoscopic Rabbit Model of Cavitary Tuberculosis

(2008) G. G. Nedeltchev et al.   INFECTION AND IMMUNITY

Bovine tuberculosis as a model for human tuberculosis: advantages over small animal models

(2008) Ildiko Van Rhijn et al.   MICROBES AND INFECTION

Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes

(2008) Heather D Hickman et al.   NATURE IMMUNOLOGY

ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes

(2008) W. W. Reiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA