Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques

Comparison of conventional Ziehl–Neelsen method of acid fast bacilli with modified bleach method in tuberculous lymphadenitis

(2017) SheetalG Gole et al.   Journal of Cytology

Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1–Expressing Immune Cells

(2017) Joshua T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis

(2017) Constance J. Martin et al.   mBio

Animal Models for Tuberculosis in Translational and Precision Medicine

(2017) Lingjun Zhan et al.   Frontiers in Microbiology

A Functional Role for Antibodies in Tuberculosis

(2016) Lenette L. Lu et al.   CELL

Lymph node - an organ for T-cell activation and pathogen defense

(2016) Georg Gasteiger et al.   IMMUNOLOGICAL REVIEWS

Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis

(2016) Thomas R. Lerner et al.   JOURNAL OF CLINICAL INVESTIGATION

Relationship Between HIV Coinfection, Interleukin 10 Production, andMycobacterium tuberculosisin Human Lymph Node Granulomas

(2016) Collin R. Diedrich et al.   JOURNAL OF INFECTIOUS DISEASES

Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography

(2016) Hanif Esmail et al.   NATURE MEDICINE

PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis

(2016) Philana Ling Lin et al.   PLoS Pathogens

Microscopic Observation Drug Susceptibility Assay for Rapid Diagnosis of Lymph Node Tuberculosis and Detection of Drug Resistance

(2015) Daniela E. Kirwan et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis

(2015) Deepak Kaushal et al.   Nature Communications

Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization

(2015) Hannah Priyadarshini Gideon et al.   PLoS Pathogens

GeneXpert MTB/RIF Assay for the Diagnosis of Tuberculous Lymphadenitis on Concentrated Fine Needle Aspirates in High Tuberculosis Burden Settings

(2015) Mulualem Tadesse et al.   PLoS One

Increased Cellular Activity in Thoracic Lymph Nodes in Early Human Latent Tuberculosis Infection

(2014) Nasrin Ghesani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Early Changes by 18Fluorodeoxyglucose Positron Emission Tomography Coregistered with Computed Tomography Predict Outcome after Mycobacterium tuberculosis Infection in Cynomolgus Macaques

(2014) M. T. Coleman et al.   INFECTION AND IMMUNITY

Latent Tuberculosis Infection: Myths, Models, and Molecular Mechanisms

(2014) N. K. Dutta et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis

(2014) M. T. Coleman et al.   Science Translational Medicine

Modeling Tuberculosis in Nonhuman Primates

(2014) C. A. Scanga et al.   Cold Spring Harbor Perspectives in Medicine

Unexpected Role for IL-17 in Protective Immunity against Hypervirulent Mycobacterium tuberculosis HN878 Infection

(2014) Radha Gopal et al.   PLoS Pathogens

The Immune Response in Tuberculosis

(2013) Anne O'Garra et al.   Annual Review of Immunology

Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens

(2013) Philana Ling Lin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

(2013) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Predicting lymph node output efficiency using systems biology

(2013) Chang Gong et al.   JOURNAL OF THEORETICAL BIOLOGY

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

(2013) Philana Ling Lin et al.   NATURE MEDICINE

18-fluorodeoxyglucose positron emission tomography for tuberculosis diagnosis and management: a case series

(2013) Scott K Heysell et al.   BMC Pulmonary Medicine

Essential yet limited role for CCR2+ inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming

(2013) Miriam Samstein et al.   eLife

CD4 T Cell Depletion Exacerbates Acute Mycobacterium tuberculosis While Reactivation of Latent Infection Is Dependent on Severity of Tissue Depletion in Cynomolgus Macaques

(2012) Philana Ling Lin et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Activated B Cells in the Granulomas of Nonhuman Primates Infected with Mycobacterium tuberculosis

(2012) Jia Yao Phuah et al.   AMERICAN JOURNAL OF PATHOLOGY

A Spatially-Organized Multicellular Innate Immune Response in Lymph Nodes Limits Systemic Pathogen Spread

(2012) Wolfgang Kastenmüller et al.   CELL

Diagnosis of tuberculous lymphadenitis using fine needle aspiration biopsy

(2012) J. Knox et al.   INTERNAL MEDICINE JOURNAL

Lymph Node Macrophages

(2012) Elizabeth E. Gray et al.   Journal of Innate Immunity

Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques

(2012) P. L. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current Diagnosis and Management of Peripheral Tuberculous Lymphadenitis

(2011) J.-M. Fontanilla et al.   CLINICAL INFECTIOUS DISEASES

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus

(2010) Matteo Iannacone et al.   NATURE

Epidemiology of Extrapulmonary Tuberculosis in the United States, 1993–2006

(2009) Heather M. Peto et al.   CLINICAL INFECTIOUS DISEASES

Conduits Mediate Transport of Low-Molecular-Weight Antigen to Lymph Node Follicles

(2009) Ramon Roozendaal et al.   IMMUNITY

Dynamics of T Cell, Antigen-Presenting Cell, and Pathogen Interactions during Recall Responses in the Lymph Node

(2009) Tatyana Chtanova et al.   IMMUNITY

Mesenteric Lymph Nodes Confine Dendritic Cell-Mediated Dissemination of Salmonella enterica Serovar Typhimurium and Limit Systemic Disease in Mice

(2009) S. Voedisch et al.   INFECTION AND IMMUNITY

Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model

(2009) P. L. Lin et al.   INFECTION AND IMMUNITY

Bovine tuberculosis as a model for human tuberculosis: advantages over small animal models

(2008) Ildiko Van Rhijn et al.   MICROBES AND INFECTION

Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes

(2008) Heather D Hickman et al.   NATURE IMMUNOLOGY

ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes

(2008) W. W. Reiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA