Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1–Expressing Immune Cells

Integrin-based therapeutics: biological basis, clinical use and new drugs

(2016) Klaus Ley et al.   NATURE REVIEWS DRUG DISCOVERY

PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis

(2016) Philana Ling Lin et al.   PLoS Pathogens

Immunometabolism in Tuberculosis

(2016) Lanbo Shi et al.   Frontiers in Immunology

A Sterilizing Tuberculosis Treatment Regimen Is Associated with Faster Clearance of Bacteria in Cavitary Lesions in Marmosets

(2015) Laura E. Via et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Granzyme B-expressing neutrophils correlate with bacterial load in granulomas fromMycobacterium tuberculosis-infected cynomolgus macaques

(2015) Joshua T. Mattila et al.   CELLULAR MICROBIOLOGY

Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses

(2015) Anne Lenaerts et al.   IMMUNOLOGICAL REVIEWS

The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-γ

(2015) Rui Appelberg et al.   IMMUNOLOGY

Imaging in tuberculosis

(2015) Evangelia Skoura et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling

(2015) Brendan Prideaux et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites

(2015) Isaac G. Sakala et al.   JOURNAL OF IMMUNOLOGY

The association between sterilizing activity and drug distribution into tuberculosis lesions

(2015) Brendan Prideaux et al.   NATURE MEDICINE

Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery

(2015) Meenal Datta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Within patient microevolution of Mycobacterium tuberculosis correlates with heterogeneous responses to treatment

(2015) Qingyun Liu et al.   Scientific Reports

Early Changes by 18Fluorodeoxyglucose Positron Emission Tomography Coregistered with Computed Tomography Predict Outcome after Mycobacterium tuberculosis Infection in Cynomolgus Macaques

(2014) M. T. Coleman et al.   INFECTION AND IMMUNITY

In Vivo Prediction of Tuberculosis-Associated Cavity Formation in Rabbits

(2014) Brian Luna et al.   JOURNAL OF INFECTIOUS DISEASES

PET Imaging of Very Late Antigen-4 in Melanoma: Comparison of 68Ga- and 64Cu-Labeled NODAGA and CB-TE1A1P-LLP2A Conjugates

(2014) W. Beaino et al.   JOURNAL OF NUCLEAR MEDICINE

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis

(2014) M. T. Coleman et al.   Science Translational Medicine

PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis

(2014) R. Y. Chen et al.   Science Translational Medicine

Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens

(2013) Philana Ling Lin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Differential Virulence and Disease Progression following Mycobacterium tuberculosis Complex Infection of the Common Marmoset (Callithrix jacchus)

(2013) Laura E. Via et al.   INFECTION AND IMMUNITY

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

(2013) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

(2013) Philana Ling Lin et al.   NATURE MEDICINE

FDG-PET Imaging in HIV Infection and Tuberculosis

(2013) Mike Sathekge et al.   SEMINARS IN NUCLEAR MEDICINE

A computational pipeline for quantification of pulmonary infections in small animal models using serial PET-CT imaging

(2013) Ulas Bagci et al.   EJNMMI Research

Activated B Cells in the Granulomas of Nonhuman Primates Infected with Mycobacterium tuberculosis

(2012) Jia Yao Phuah et al.   AMERICAN JOURNAL OF PATHOLOGY

Infection Dynamics and Response to Chemotherapy in a Rabbit Model of Tuberculosis using [18F]2-Fluoro-Deoxy-d-Glucose Positron Emission Tomography and Computed Tomography

(2012) Laura E. Via et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Macrophages participate in IL-17-mediated inflammation

(2011) Jobert G. Barin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The α4β1 Integrin in Localization ofMycobacterium tuberculosis–Specific T Helper Type 1 Cells to the Human Lung

(2010) Jessica R. Walrath et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model

(2009) P. L. Lin et al.   INFECTION AND IMMUNITY

Activated Integrin VLA-4 Localizes to the Lamellipodia and Mediates T Cell Migration on VCAM-1

(2009) Y.-M. Hyun et al.   JOURNAL OF IMMUNOLOGY

An α4β1 integrin antagonist decreases airway inflammation in ovalbumin-exposed mice

(2008) Nicholas J. Kenyon et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY