Structure of the TRPV1 ion channel determined by electron cryo-microscopy

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

Targeting TRP channels for pain relief

(2013) Jill-Desiree Brederson et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids

(2013) Erhu Cao et al.   NEURON

Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles

(2013) Xiao-chen Bai et al.   eLife

Exome Sequencing Reveals Mutations in TRPV3 as a Cause of Olmsted Syndrome

(2012) Zhimiao Lin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel

(2012) Hitoshi Inada et al.   BIOCHEMISTRY

Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel

(2012) Stepana Boukalova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

China must provide education on HIV

(2012) Jian Zhang et al.   NATURE

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Amphipols From A to Z*

(2011) J.-L. Popot et al.   Annual Review of Biophysics

Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1

(2011) Thorsten Althoff et al.   EMBO JOURNAL

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Increased Basal Activity Is a Key Determinant in the Severity of Human Skeletal Dysplasia Caused by TRPV4 Mutations

(2011) Stephen Loukin et al.   PLoS One

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Kinetic and Energetic Analysis of Thermally Activated TRPV1 Channels

(2010) Jing Yao et al.   BIOPHYSICAL JOURNAL

3.3 Å Cryo-EM Structure of a Nonenveloped Virus Reveals a Priming Mechanism for Cell Entry

(2010) Xing Zhang et al.   CELL

A 3.5-nm Structure of Rat TRPV4 Cation Channel Revealed by Zernike Phase-contrast Cryoelectron Microscopy

(2010) Hideki Shigematsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conserved Residues within the Putative S4–S5 Region Serve Distinct Functions among Thermosensitive Vanilloid Transient Receptor Potential (TRPV) Channels

(2010) Stepana Boukalova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ion Channel Voltage Sensors: Structure, Function, and Pathophysiology

(2010) William A. Catterall   NEURON

Transient receptor potential channelopathies

(2010) Bernd Nilius et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Structural determinants of gating in the TRPV1 channel

(2009) Héctor Salazar et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure–functional intimacies of transient receptor potential channels

(2009) Ramon Latorre et al.   QUARTERLY REVIEWS OF BIOPHYSICS

A primer on ankyrin repeat function in TRP channels and beyond

(2008) Rachelle Gaudet   Molecular BioSystems

Sensing voltage across lipid membranes

(2008) Kenton J. Swartz   NATURE

3.88 Å structure of cytoplasmic polyhedrosis virus by cryo-electron microscopy

(2008) Xuekui Yu et al.   NATURE

TRPV1 shows dynamic ionic selectivity during agonist stimulation

(2008) Man-Kyo Chung et al.   NATURE NEUROSCIENCE

A Yeast Genetic Screen Reveals a Critical Role for the Pore Helix Domain in TRP Channel Gating

(2008) Benjamin R. Myers et al.   NEURON

Structure of TRPV1 channel revealed by electron cryomicroscopy

(2008) V. Y. Moiseenkova-Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies

(2008) Abhiram Dukkipati et al.   PROTEIN EXPRESSION AND PURIFICATION