Targeting STAT3 in cancer: how successful are we?

JSI-124 inhibits glioblastoma multiforme cell proliferation through G2/M cell cycle arrest and apoptosis augmentation

(2010) Yuhang Su et al.   CANCER BIOLOGY & THERAPY

Transcription Factor Oligodeoxynucleotides to NF-κB Inhibit Transcription of IL-8 in Bronchial Cells

(2008) Valentino Bezzerri et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Discovery of the catechol structural moiety as a Stat3 SH2 domain inhibitor by virtual screening

(2008) Wenshan Hao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Indirubin-3′-monoxime, a derivative of a Chinese anti-leukemia medicine, inhibits Notch1 signaling

(2008) Mi-Jee Lee et al.   CANCER LETTERS

Growth inhibition of human hepatocellular carcinoma cells by blocking STAT3 activation with decoy-ODN

(2008) Xiaoxia Sun et al.   CANCER LETTERS

STAT3 as a target for inducing apoptosis in solid and hematological tumors

(2008) Khandaker Al Zaid Siddiquee et al.   CELL RESEARCH

Molecular Approaches towards the Inhibition of the Signal Transducer and Activator of Transcription 3 (Stat3) Protein

(2008) Steven Fletcher et al.   ChemMedChem

Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer

(2008) Tingyan Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-κB and STAT3 pathways in Hodgkin's lymphoma cells

(2008) Gerardo G. Mackenzie et al.   INTERNATIONAL JOURNAL OF CANCER

Cucurbitacin I Inhibits Stat3 and Induces Apoptosis in Sézary Cells

(2008) Marloes S. van Kester et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Decoy oligodeoxynucleotide targeting activator protein-1 (AP-1) attenuates intestinal inflammation in murine experimental colitis

(2008) Ichiro Moriyama et al.   LABORATORY INVESTIGATION

Monomeric Recombinant Peptide Aptamers Are Required for Efficient Intracellular Uptake and Target Inhibition

(2008) C. Borghouts et al.   MOLECULAR CANCER RESEARCH

Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes

(2008) Amanda M Gonzales et al.   Nutrition & Metabolism

Paradigm shifts in the cell biology of STAT signaling

(2008) Pravin B. Sehgal   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Design, synthesis, and studies of small molecule STAT3 inhibitors

(2007) Deepak Bhasin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS