Natural products and their derivatives regulating the janus kinase/signal transducer and activator of transcription pathway

Kurarinone regulates immune responses through regulation of the JAK/STAT and TCR-mediated signaling pathways

(2013) Byung-Hak Kim et al.   BIOCHEMICAL PHARMACOLOGY

Current-driven dynamics of chiral ferromagnetic domain walls

(2013) Satoru Emori et al.   NATURE MATERIALS

Involvement of JAK/STAT signaling in the pathogenesis of inflammatory bowel disease

(2013) Mehmet Coskun et al.   PHARMACOLOGICAL RESEARCH

Withaferin A inhibits JAK/STAT3 signaling and induces apoptosis of human renal carcinoma Caki cells

(2012) Hee Jung Um et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Small Molecule Activators of the Janus Kinase/Signal Transducer and Activator of Transcription Pathway Using a Cell-Based Screen

(2012) Zheng Fu Tai et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

STAT-3 Inhibitory Bisabolanes from Carthamus glaucus

(2012) Orazio Taglialatela-Scafati et al.   JOURNAL OF NATURAL PRODUCTS

Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells

(2012) Sangkil Nam et al.   Molecular Oncology

Flavanocoumarins from Guazuma ulmifolia bark and evaluation of their affinity for STAT1

(2012) Mariateresa Maldini et al.   PHYTOCHEMISTRY

Curcumin Blocks Small Cell Lung Cancer Cells Migration, Invasion, Angiogenesis, Cell Cycle and Neoplasia through Janus Kinase-STAT3 Signalling Pathway

(2012) Cheng-Liang Yang et al.   PLoS One

Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT Pathways

(2011) Taiga Tamiya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Homosecoiridoids from the Flower Buds ofLonicera japonica

(2011) Yang Yu et al.   JOURNAL OF NATURAL PRODUCTS

Effects of Flavonoids on Matrix Metalloproteinase-13 Expression of Interleukin-1β–Treated Articular Chondrocytes and Their Cellular Mechanisms: Inhibition of c-Fos/AP-1 and JAK/STAT Signaling Pathways

(2011) Hyun Lim et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Cardamonin suppresses nitric oxide production via blocking the IFN-γ/STAT pathway in endotoxin-challenged peritoneal macrophages of ICR mice

(2011) Amane Takahashi et al.   LIFE SCIENCES

Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway

(2010) Y. Dong et al.   CARCINOGENESIS

Inhibition of lipopolysaccharide-induced inflammatory responses by piperine

(2010) Gi-Sang Bae et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of Th1 and Th17 Cell Differentiation and Amelioration of Experimental Autoimmune Encephalomyelitis by Natural Product Compound Berberine

(2010) X. Qin et al.   JOURNAL OF IMMUNOLOGY

Luteolin inhibits cytokine expression in endotoxin/cytokine-stimulated microglia

(2010) Tsung-Kuei Kao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapy

(2010) R R Ruela-de-Sousa et al.   Cell Death & Disease

The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury

(2009) Katerina Vafeiadou et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Two enone fatty acids isolated from Gracilaria verrucosa suppress the production of inflammatory mediators by down-regulating NF-κB and STAT1 activity in lipopolysaccharide-stimulated RAW 264.7 cells

(2009) Hye-Ja Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Capsaicin inhibits the IL-6/STAT3 pathway by depleting intracellular gp130 pools through endoplasmic reticulum stress

(2009) Hyun Kyoung Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cucurbitane-Type Triterpenoids from the Stems ofCucumis melo

(2009) Chuan Chen et al.   JOURNAL OF NATURAL PRODUCTS

Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts

(2009) Yoshitaka Hosokawa et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation

(2009) Xuejun Xu et al.   PLoS One

Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation

(2008) Megumi Funakoshi-Tago et al.   BIOCHEMICAL PHARMACOLOGY

The Year Ahead

(2008) F. J. Rauscher   CANCER RESEARCH

HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride

(2008) Konstantin Tsoyi et al.   CELLULAR SIGNALLING

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

(2008) Kavon Rezai-Zadeh et al.   Journal of Neuroinflammation

Inteferons pen the JAK–STAT pathway

(2008) Christian Schindler et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Anthraquinones of edible wild vegetable Cassia tora stimulate proliferation of human CD4+ T lymphocytes and secretion of interferon-gamma or interleukin 10

(2007) Jaw-Ming Cherng et al.   FOOD CHEMISTRY