MicroRNA and ROS Crosstalk in Cardiac and Pulmonary Diseases

MicroRNA-126 enhances the biological function of endothelial progenitor cells under oxidative stress via PI3K/Akt/GSK-3β and ERK1/2 signaling pathways

(2020) Qinqin Wu et al.   Bosnian Journal of Basic Medical Sciences

Oxidative Stress-Responsive MicroRNAs in Heart Injury

(2020) Branislav Kura et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genome-wide integration of microRNA and transcriptomic profiles of differentiating human alveolar epithelial cells

(2020) Alessandra Castaldi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MiR-30c/PGC-1β protects against diabetic cardiomyopathy via PPARα

(2019) Zhongwei Yin et al.   Cardiovascular Diabetology

MicroRNA‑144 attenuates cardiac ischemia/reperfusion injury by targeting FOXO1

(2019) Lusha E et al.   Experimental and Therapeutic Medicine

Ligustrazin increases lung cell autophagy and ameliorates paraquat-induced pulmonary fibrosis by inhibiting PI3K/Akt/mTOR and hedgehog signalling via increasing miR-193a expression

(2019) Ming-wei Liu et al.   BMC Pulmonary Medicine

MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer

(2019) Lu Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Down‐regulation of miR‐200c attenuates AngII‐induced cardiac hypertrophy via targeting the MLCK‐mediated pathway

(2019) Shan Hu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Tumor suppressor function of miR‑129‑5p in lung cancer

(2019) Ge Li et al.   Oncology Letters

miR-144 regulates oxidative stress tolerance of thalassemic erythroid cell via targeting NRF2

(2019) Kanitta Srinoun et al.   ANNALS OF HEMATOLOGY

Oxidant/Antioxidant Disequilibrium in Idiopathic Pulmonary Fibrosis Pathogenesis

(2019) Paolo Cameli et al.   INFLAMMATION

microRNA‐340‐5p inhibits hypoxia/reoxygenation‐induced apoptosis and oxidative stress in cardiomyocytes by regulating the Act1/NF‐κB pathway

(2019) Dong Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MiR-34c acts as a tumor suppressor in non-small cell lung cancer by inducing endoplasmic reticulum stress through targeting HMGB1

(2019) Li Tu et al.   OncoTargets and Therapy

Morin Protects Human Respiratory Cells from PM2.5 Induced Genotoxicity by Mitigating ROS and Reverting Altered miRNA Expression

(2019) Indhumathi Veerappan et al.   International Journal of Environmental Research and Public Health

Pleiotropic microRNA-21 in pulmonary remodeling: novel insights for molecular mechanism and present advancements

(2019) Congshan Jiang et al.   Allergy Asthma and Clinical Immunology

MicroRNA-122 promotes cardiomyocyte hypertrophy via targeting FoxO3

(2019) Guixian Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The extensive role of miR-155 in malignant and non-malignant diseases

(2019) Diana Gulei et al.   MOLECULAR ASPECTS OF MEDICINE

miR-154-5p Functions as an Important Regulator of Angiotensin II-Mediated Heart Remodeling

(2019) Que Wang et al.   Oxidative Medicine and Cellular Longevity

MiR-421 inhibition protects H9c2 cells against hypoxia/reoxygenation-induced oxidative stress and apoptosis by targeting Sirt3

(2019) Yu Liu et al.   PERFUSION-UK

Aloe-emodin attenuates myocardial infarction and apoptosis via up-regulating miR-133 expression

(2019) Yang Yu et al.   PHARMACOLOGICAL RESEARCH

MiR‑370 inhibits the oxidative stress and apoptosis of cardiac myocytes induced by hydrogen peroxide by targeting FOXO1

(2019) Zhanjun Qiu et al.   Experimental and Therapeutic Medicine

Serum Exosomal MicroRNAs Predict Acute Respiratory Distress Syndrome Events in Patients with Severe Community-Acquired Pneumonia

(2019) Xu Wu et al.   Biomed Research International

The Different Roles of miRNA-92a-2-5p and let-7b-5p in Mitochondrial Translation in db/db Mice

(2019) Huaping Li et al.   Molecular Therapy-Nucleic Acids

Grp78 Loss in Epithelial Progenitors Reveals an Age-Linked Role for ER Stress in Pulmonary Fibrosis

(2019) Zea Borok et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Up-regulation of microRNA-203 inhibits myocardial fibrosis and oxidative stress in mice with diabetic cardiomyopathy through the inhibition of PI3K/Akt signaling pathway via PIK3CA

(2019) Xubin Yang et al.   GENE

PM2.5 inhibits SOD1 expression by up-regulating microRNA-206 and promotes ROS accumulation and disease progression in asthmatic mice

(2019) Lei Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Role of MicroRNAs in Diabetes-Related Oxidative Stress

(2019) Mirza Muhammad Fahd Qadir et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miR-129-5p improves cardiac function in rats with chronic heart failure through targeting HMGB1

(2019) Na Xiao et al.   MAMMALIAN GENOME

Overexpression of Mitochondrial Calcium Uniporter Causes Neuronal Death

(2019) Veronica Granatiero et al.   Oxidative Medicine and Cellular Longevity

MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer

(2019) Fu-Gang Duan et al.   Cell Death & Disease

Astragaloside-IV protects H9C2(2-1) cardiomyocytes from high glucose-induced injury via miR-34a-mediated autophagy pathway

(2019) Yaobin Zhu et al.   Artificial Cells Nanomedicine and Biotechnology

Circular RNA ANKRD36 attends to lipopolysaccharide‐aroused MRC‐5 cell injury via regulating microRNA‐31‐3p

(2019) Rui Guo et al.   BIOFACTORS

Mitochondrial dysfunction and oxidative stress in heart disease

(2019) Jessica N. Peoples et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Overview of microRNA-199a Regulation in Cancer

(2019) Qiwen Wang et al.   Cancer Management and Research

Myocardial infarction-induced microRNA-enriched exosomes contribute to cardiac Nrf2 dysregulation in chronic heart failure

(2018) Changhai Tian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Role of Sirtuins in Antioxidant and Redox Signaling

(2018) Chandra K. Singh et al.   ANTIOXIDANTS & REDOX SIGNALING

Liver X receptor α is targeted by microRNA-1 to inhibit cardiomyocyte apoptosis through a ROS-mediated mitochondrial pathway

(2018) Yongxia Cheng et al.   Biochemistry and Cell Biology

LAZ3 protects cardiac remodeling in diabetic cardiomyopathy via regulating miR-21/PPARa signaling

(2018) Lu Gao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Exosomes—Small Players, Big Sound

(2018) Diana Gulei et al.   BIOCONJUGATE CHEMISTRY

Current Mechanistic Concepts in Ischemia and Reperfusion Injury

(2018) Meng-Yu Wu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-208a Correlates Apoptosis and Oxidative Stress Induced by H2O2 through Protein Tyrosine Kinase/Phosphatase Balance in Cardiomyocytes

(2018) Aijun Liu et al.   International Heart Journal

A novel molecular mechanism of microRNA-21 inducing pulmonary fibrosis and human pulmonary fibroblast extracellular matrix through transforming growth factor β1-mediated SMADs activation

(2018) Jun Zhou et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

miR-155 Modulates Cockroach Allergen– and Oxidative Stress–Induced Cyclooxygenase-2 in Asthma

(2018) Lipeng Qiu et al.   JOURNAL OF IMMUNOLOGY

Developmental Decline in the MicroRNA 199a (miR-199a)/miR-214 Cluster in Human Fetal Lung Promotes Type II Cell Differentiation by Upregulating Key Transcription Factors

(2018) Ritu Mishra et al.   MOLECULAR AND CELLULAR BIOLOGY

The expression of microRNA-23a regulates acute myocardial infarction in patients and in�vitro through targeting PTEN

(2018) Shengli Li et al.   Molecular Medicine Reports

Human dihydrolipoamide dehydrogenase (E3) deficiency: Novel insights into the structural basis and molecular pathomechanism

(2018) Attila Ambrus et al.   NEUROCHEMISTRY INTERNATIONAL

Endothelial and cardiac progenitor cells for cardiovascular repair: A controversial paradigm in cell therapy

(2018) Vanessa Bianconi et al.   PHARMACOLOGY & THERAPEUTICS

Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets

(2018) Vikas Mishra et al.   PHARMACOLOGY & THERAPEUTICS

The Role of miRNA-132 against Apoptosis and Oxidative Stress in Heart Failure

(2018) Xuelei Liu et al.   Biomed Research International

SIRT1/PGC-1α Signaling Promotes Mitochondrial Functional Recovery and Reduces Apoptosis after Intracerebral Hemorrhage in Rats

(2018) Yang Zhou et al.   Frontiers in Molecular Neuroscience

Downregulation of TLR4 by miR-181a Provides Negative Feedback Regulation to Lipopolysaccharide-Induced Inflammation

(2018) Kangfeng Jiang et al.   Frontiers in Pharmacology

MiR-21 protected against diabetic cardiomyopathy induced diastolic dysfunction by targeting gelsolin

(2018) Beibei Dai et al.   Cardiovascular Diabetology

Targeting Peroxisome Proliferator Activated Receptor α (PPAR α) for the Prevention of Mitochondrial Impairment and Hypertrophy in Cardiomyocytes

(2018) Dipak Kar et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Exosomes Derived from miR-214-Enriched Bone Marrow-Derived Mesenchymal Stem Cells Regulate Oxidative Damage in Cardiac Stem Cells by Targeting CaMKII

(2018) Yan Wang et al.   Oxidative Medicine and Cellular Longevity

Upregulated expression of miR-421 is associated with poor prognosis in non-small-cell lung cancer

(2018) Yunxia Li et al.   Cancer Management and Research

Interplay of N acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs

(2018) Tahir Ali et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Absence of miR-223-3p ameliorates hypoxia-induced injury through repressing cardiomyocyte apoptosis and oxidative stress by targeting KLF15

(2018) Qing Tang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

MicroRNA miR-24-3p Reduces Apoptosis and Regulates Keap1-Nrf2 Pathway in Mouse Cardiomyocytes Responding to Ischemia/Reperfusion Injury

(2018) Xu Xiao et al.   Oxidative Medicine and Cellular Longevity

Chidamide-induced ROS accumulation and miR-129-3p-dependent cell cycle arrest in non-small lung cancer cells

(2018) Yueh-Feng Wu et al.   PHYTOMEDICINE

Long noncoding RNA FOXD3-AS1 regulates oxidative stress-induced apoptosis via sponging microRNA-150

(2017) Duo Zhang et al.   FASEB JOURNAL

Physiological role of reactive oxygen species as promoters of natural defenses

(2017) Jérôme Roy et al.   FASEB JOURNAL

MicroRNA-31 promotes adverse cardiac remodeling and dysfunction in ischemic heart disease

(2017) Eliana C. Martinez et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Impact of Oxidative Stress on the Heart and Vasculature

(2017) Thomas Münzel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Suberoylanilide hydroxamic acid induces thioredoxin1-mediated apoptosis in lung cancer cells via up-regulation of miR-129-5p

(2017) Bo Ra You et al.   MOLECULAR CARCINOGENESIS

miR-23a Regulates Cardiomyocyte Apoptosis by Targeting Manganese Superoxide Dismutase

(2017) Bo Long et al.   MOLECULES AND CELLS

MicroRNA Regulation of Oxidative Stress-Induced Cellular Senescence

(2017) Huaije Bu et al.   Oxidative Medicine and Cellular Longevity

Reduction–oxidation pathways involved in cancer development: a systematic review of literature reviews

(2017) Xīn Gào et al.   Oncotarget

Thymoquinone, as an anticancer molecule: from basic research to clinical investigation

(2017) Md. Asaduzzaman Khan et al.   Oncotarget

Suppression of microRNA-16 protects against acute myocardial infarction by reversing beta2-adrenergic receptor down-regulation in rats

(2017) Jiaqi Liu et al.   Oncotarget

MicroRNA-98 negatively regulates myocardial infarction-induced apoptosis by down-regulating Fas and caspase-3

(2017) Chuan Sun et al.   Scientific Reports

miR-503 Is Involved in the Protective Effect of Phase II Enzyme Inducer (CPDT) in Diabetic Cardiomyopathy via Nrf2/ARE Signaling Pathway

(2017) Ying Miao et al.   Biomed Research International

Mitochondria Associated MicroRNA Expression Profiling of Heart Failure

(2017) Xiaoxia Wang et al.   Biomed Research International

Thymoquinone as a Potential Adjuvant Therapy for Cancer Treatment: Evidence from Preclinical Studies

(2017) A.G.M. Mostofa et al.   Frontiers in Pharmacology

miR-185 mediates lung epithelial cell death after oxidative stress

(2016) Duo Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

P66Shc-Induced MicroRNA-34a Causes Diabetic Endothelial Dysfunction by Downregulating Sirtuin1Highlights

(2016) Qiuxia Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial deletion of protein tyrosine phosphatase-1B protects against pressure overload-induced heart failure in mice

(2016) Rajinikanth Gogiraju et al.   CARDIOVASCULAR RESEARCH

Oxidative stress, microRNAs and cytosolic calcium homeostasis

(2016) Alessandra Magenta et al.   CELL CALCIUM

2-Oxoglutarate dehydrogenase is a more significant source of O 2 ·− /H 2 O 2 than pyruvate dehydrogenase in cardiac and liver tissue

(2016) Ryan J. Mailloux et al.   FREE RADICAL BIOLOGY AND MEDICINE

Upregulation of microRNA-22 contributes to myocardial ischemia-reperfusion injury by interfering with the mitochondrial function

(2016) Jian-Kui Du et al.   FREE RADICAL BIOLOGY AND MEDICINE

Irradiation with UV-C inhibits TNF-α-dependent activation of the NF-κB pathway in a mechanism potentially mediated by reactive oxygen species

(2016) Katarzyna Szoltysek et al.   GENES TO CELLS

Polygonatum odoratum lectin induces apoptosis and autophagy by regulation of microRNA-1290 and microRNA-15a-3p in human lung adenocarcinoma A549 cells

(2016) Lei Wu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

miR-106a promotes cardiac hypertrophy by targeting mitofusin 2

(2016) Xiaoxiang Guan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Physiological and pathological cardiac hypertrophy

(2016) Ippei Shimizu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MiR-145 and miR-203 represses TGF-β-induced epithelial-mesenchymal transition and invasion by inhibiting SMAD3 in non-small cell lung cancer cells

(2016) Haibo Hu et al.   LUNG CANCER

The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis

(2016) G Li et al.   ONCOGENE

miR-99a regulates ROS-mediated invasion and migration of lung adenocarcinoma cells by targeting NOX4

(2016) MEI SUN et al.   ONCOLOGY REPORTS

Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion

(2016) Lalchhandami Tochhawng et al.   Oncotarget

Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling

(2016) Poyil Pratheeshkumar et al.   Oncotarget

TLR4/ROS/miRNA-21 pathway underlies lipopolysaccharide instructed primary tumor outgrowth in lung cancer patients

(2016) Xianqi Zhang et al.   Oncotarget

Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-PDCD4 signaling pathway

(2016) Poyil Pratheeshkumar et al.   Oncotarget

Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs

(2016) Heedoo Lee et al.   Scientific Reports

Concise Review: Endothelial Progenitor Cells in Regenerative Medicine: Applications and Challenges

(2016) Mark Seow Khoon Chong et al.   Stem Cells Translational Medicine

Resveratrol Ameliorates Cardiac Hypertrophy by Down‐regulation of miR‐155 Through Activation of Breast Cancer Type 1 Susceptibility Protein

(2016) Yuhua Fan et al.   Journal of the American Heart Association

Restriction of Aerobic Metabolism by Acquired or Innate Arylsulfatase B Deficiency: A New Approach to the Warburg Effect

(2016) Sumit Bhattacharyya et al.   Scientific Reports

MicroRNA-155 aggravates ischemia–reperfusion injury by modulation of inflammatory cell recruitment and the respiratory oxidative burst

(2015) Steffen U. Eisenhardt et al.   BASIC RESEARCH IN CARDIOLOGY

ROS-mediated bidirectional regulation of miRNA results in distinct pathologic heart conditions

(2015) Seahyoung Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Schisandrin B shows neuroprotective effect in 6-OHDA-induced Parkinson’s disease via inhibiting the negative modulation of miR-34a on Nrf2 pathway

(2015) Qinghua Ba et al.   BIOMEDICINE & PHARMACOTHERAPY

MicroRNA-23a enhances migration and invasion through PTEN in osteosarcoma

(2015) K Tian et al.   CANCER GENE THERAPY

Pivotal role of miR-448 in the development of ROS-induced cardiomyopathy

(2015) Sergii Kyrychenko et al.   CARDIOVASCULAR RESEARCH

Mitochondrial ROS Signaling in Organismal Homeostasis

(2015) Gerald S. Shadel et al.   CELL

MicroRNA-1 aggravates cardiac oxidative stress by post-transcriptional modification of the antioxidant network

(2015) Lu Wang et al.   CELL STRESS & CHAPERONES

TGF  Triggers miR-143/145 Transfer From Smooth Muscle Cells to Endothelial Cells, Thereby Modulating Vessel Stabilization

(2015) M. Climent et al.   CIRCULATION RESEARCH

Silencing of miR-195 reduces diabetic cardiomyopathy in C57BL/6 mice

(2015) Dong Zheng et al.   DIABETOLOGIA

miR-9-5p suppresses pro-fibrogenic transformation of fibroblasts and prevents organ fibrosis by targeting NOX4 and TGFBR2

(2015) M. Fierro-Fernandez et al.   EMBO REPORTS

MicroRNA profiling unveils hyperglycaemic memory in the diabetic heart

(2015) Sarah Costantino et al.   EUROPEAN HEART JOURNAL

The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis

(2015) Chunlian Liang et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

SOD2 targeted gene editing by CRISPR/Cas9 yields Human cells devoid of MnSOD

(2015) Kimberly Cramer-Morales et al.   FREE RADICAL BIOLOGY AND MEDICINE

MiR-25 Protects Cardiomyocytes against Oxidative Damage by Targeting the Mitochondrial Calcium Uniporter

(2015) Lei Pan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective Effects of Diallyl Sulfide on Ovalbumin-Induced Pulmonary Inflammation of Allergic Asthma Mice by MicroRNA-144, -34a, and -34b/c-Modulated Nrf2 Activation

(2015) Cheng-Ying Ho et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Human mitochondrial COX1 assembly into cytochrome c oxidase at a glance

(2015) S. Dennerlein et al.   JOURNAL OF CELL SCIENCE

Oxidant stress promotes disease by activating CaMKII

(2015) Mark E. Anderson   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

APACHE Score, Severity Index of Paraquat Poisoning, and Serum Lactic Acid Concentration in the Prognosis of Paraquat Poisoning of Chinese Patients

(2015) Shuyun Xu et al.   PEDIATRIC EMERGENCY CARE

Critical role of miR-155/FoxO1/ROS axis in the regulation of non-small cell lung carcinomas

(2015) Likun Hou et al.   TUMOR BIOLOGY

Role of miR-182 in response to oxidative stress in the cell fate of human fallopian tube epithelial cells

(2015) Yugang Liu et al.   Oncotarget

Oxidative stress-mediated HMGB1 biology

(2015) Yan Yu et al.   Frontiers in Physiology

miR-150 Deficiency Protects against FAS-Induced Acute Liver Injury in Mice through Regulation of AKT

(2015) Weina Chen et al.   PLoS One

The microRNA-218~Survivin axis regulates migration, invasion, and lymph node metastasis in cervical cancer

(2015) Ryunosuke Kogo et al.   Oncotarget

The role of TGF-β1–miR-21–ROS pathway in bystander responses induced by irradiated non-small-cell lung cancer cells

(2014) Y Jiang et al.   BRITISH JOURNAL OF CANCER

Dietary flaxseed modulates the miRNA profile in irradiated and non-irradiated murine lungs

(2014) Melpo Christofidou-Solomidou et al.   CANCER BIOLOGY & THERAPY

A signaling pathway consisting of miR-551b, catalase and MUC1 contributes to acquired apoptosis resistance and chemoresistance

(2014) Xiuling Xu et al.   CARCINOGENESIS

Liver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice

(2014) Qing He et al.   Cardiovascular Diabetology

MicroRNA-133 Modulates the β 1 -Adrenergic Receptor Transduction Cascade

(2014) Alessandra Castaldi et al.   CIRCULATION RESEARCH

Chronic Arsenic Exposure and Angiogenesis in Human Bronchial Epithelial Cells via the ROS/miR-199a-5p/HIF-1α/COX-2 Pathway

(2014) Jun He et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Receptor-interacting Protein 1 Increases Chemoresistance by Maintaining Inhibitor of Apoptosis Protein Levels and Reducing Reactive Oxygen Species through a microRNA-146a-mediated Catalase Pathway

(2014) Qiong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Upregulation of miR-760 and miR-186 Is Associated with Replicative Senescence in Human Lung Fibroblast Cells

(2014) Young-Hoon Lee et al.   MOLECULES AND CELLS

Selective killing of lung cancer cells by miRNA-506 molecule through inhibiting NF-κB p65 to evoke reactive oxygen species generation and p53 activation

(2014) M Yin et al.   ONCOGENE

miR-181c Regulates the Mitochondrial Genome, Bioenergetics, and Propensity for Heart Failure In Vivo

(2014) Samarjit Das et al.   PLoS One

miR-133a Enhances the Protective Capacity of Cardiac Progenitors Cells after Myocardial Infarction

(2014) Alberto Izarra et al.   Stem Cell Reports

Epigenetic Regulation ofmiR-17∼92Contributes to the Pathogenesis of Pulmonary Fibrosis

(2013) Duaa Dakhlallah et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MicroRNA-326 Regulates Profibrotic Functions of Transforming Growth Factor-β in Pulmonary Fibrosis

(2013) Sudipta Das et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Essential Role of NADPH Oxidase-Dependent Reactive Oxygen Species Generation in Regulating MicroRNA-21 Expression and Function in Prostate Cancer

(2013) Sarvesh Jajoo et al.   ANTIOXIDANTS & REDOX SIGNALING

How Much H2O2 Is Produced by Recombinant D-Amino Acid Oxidase in Mammalian Cells?

(2013) Mikhail E. Matlashov et al.   ANTIOXIDANTS & REDOX SIGNALING

Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIPL and IAP proteins

(2013) Lan Yang et al.   APOPTOSIS

MicroRNA-145 suppresses ROS-induced Ca2+ overload of cardiomyocytes by targeting CaMKIIδ

(2013) Min-Ji Cha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Low-dose radiation activates Nrf1/2 through reactive species and the Ca2+/ERK1/2 signaling pathway in human skin fibroblast cells

(2013) Eun Kyeong Lee et al.   BMB Reports

Oxidative Stress in COPD

(2013) Paul A. Kirkham et al.   CHEST

Induction of miR-21-PDCD4 signaling by UVB in JB6 cells involves ROS-mediated MAPK pathways

(2013) Lichao Hou et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Oxidative Stress and MicroRNAs in Vascular Diseases

(2013) Alessandra Magenta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis

(2013) Anju Singh et al.   JOURNAL OF CLINICAL INVESTIGATION

RNH1 regulation of reactive oxygen species contributes to histone deacetylase inhibitor resistance in gastric cancer cells

(2013) Y Zhu et al.   ONCOGENE

miRNA-29c Suppresses Lung Cancer Cell Adhesion to Extracellular Matrix and Metastasis by Targeting Integrin β1 and Matrix Metalloproteinase2 (MMP2)

(2013) Heyong Wang et al.   PLoS One

Low-Dose Gamma Irradiation Enhances Superoxide Anion Production by Nonirradiated Cells Through TGF-β1-Dependent Bystander Signaling

(2013) Jennifer Temme et al.   RADIATION RESEARCH

miR-1 and miR-206 target different genes to have opposing roles during angiogenesis in zebrafish embryos

(2013) Cheng-Yung Lin et al.   Nature Communications

Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms

(2013) Athanasios Valavanidis et al.   International Journal of Environmental Research and Public Health

miR-199a-5p Is Upregulated during Fibrogenic Response to Tissue Injury and Mediates TGFbeta-Induced Lung Fibroblast Activation by Targeting Caveolin-1

(2013) Christian Lacks Lino Cardenas et al.   PLoS Genetics

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

(2013) Casey L. Quinlan et al.   Redox Biology

Redox and Reactive Oxygen Species Regulation of Mitochondrial Cytochrome c Oxidase Biogenesis

(2012) Myriam Bourens et al.   ANTIOXIDANTS & REDOX SIGNALING

MicroRNA-21 Modulates the Levels of Reactive Oxygen Species by Targeting SOD3 and TNF 

(2012) X. Zhang et al.   CANCER RESEARCH

SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway

(2012) Antonio Cittadini et al.   CARDIOVASCULAR RESEARCH

MicroRNA-199a-5p Is Associated With Hypoxia-Inducible Factor-1α Expression in Lungs From Patients With COPD

(2012) Shiro Mizuno et al.   CHEST

Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylation

(2012) Jun He et al.   EMBO REPORTS

Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation

(2012) Min Ling et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide

(2012) Liang-Jun Yan et al.   FREE RADICAL RESEARCH

Lung Oxidative Damage by Hypoxia

(2012) O. F. Araneda et al.   Oxidative Medicine and Cellular Longevity

MicroRNA-145 Protects Cardiomyocytes against Hydrogen Peroxide (H2O2)-Induced Apoptosis through Targeting the Mitochondria Apoptotic Pathway

(2012) Ruotian Li et al.   PLoS One

Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene

(2012) Jimmy Fourtounis et al.   RESPIRATORY RESEARCH

Participation of miR-200 in Pulmonary Fibrosis

(2011) Shanzhong Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

Arsenite induces cell transformation by reactive oxygen species, AKT, ERK1/2, and p70S6K1

(2011) Richard L. Carpenter et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1

(2011) Huaqing Zhu et al.   CARDIOVASCULAR RESEARCH

microRNAs in hypertrophy and heart failure

(2011) Michael V G Latronico et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

MicroRNA changes in human arterial endothelial cells with senescence: Relation to apoptosis, eNOS and inflammation

(2011) Catarina Rippe et al.   EXPERIMENTAL GERONTOLOGY

Stimulation of reactive oxygen species generation by disease-causing mutations of lipoamide dehydrogenase

(2011) Attila Ambrus et al.   HUMAN MOLECULAR GENETICS

Integrating mechanisms of pulmonary fibrosis

(2011) Thomas A. Wynn   JOURNAL OF EXPERIMENTAL MEDICINE

TNF Mediates the Sustained Activation of Nrf2 in Human Monocytes

(2011) S. A. Rushworth et al.   JOURNAL OF IMMUNOLOGY

Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study

(2010) Lei Kong et al.   ACTA DIABETOLOGICA

MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration

(2010) Joy Sarkar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inhibition and Role of let-7d in Idiopathic Pulmonary Fibrosis

(2010) Kusum V. Pandit et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

High-Mobility Group Box 1, Oxidative Stress, and Disease

(2010) Daolin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

Advances in chemotherapy in advanced non-small-cell lung cancer

(2010) Paolo Maione et al.   EXPERT OPINION ON PHARMACOTHERAPY

A Novel Function of Sphingosine Kinase 1 Suppression of JNK Activity in Preventing Inflammation and Injury

(2010) Anke Di et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

4-Hydroxy-2-nonenal protects against cardiac ischemia–reperfusion injury via the Nrf2-dependent pathway

(2010) Yan Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Induction of Bystander Response in Human Glioma Cells using High-Energy Electrons: A Role for TGF-β1

(2010) M. D. Gow et al.   RADIATION RESEARCH

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGF 1-induced fibroblast differentiation into myofibroblasts

(2010) N. Amara et al.   THORAX

MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts

(2009) Scot J. Matkovich et al.   CIRCULATION RESEARCH

Resveratrol inhibits right ventricular hypertrophy induced by monocrotaline in rats

(2009) Dan-Li Yang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

MicroRNA-21 protects against the H2O2-induced injury on cardiac myocytes via its target gene PDCD4

(2009) Yunhui Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid

(2009) Attila Ambrus et al.   JOURNAL OF NEUROCHEMISTRY

The p53-p21Cip1/WAF1 pathway is necessary for cellular senescence induced by the inhibition of protein kinase CKII in human colon cancer cells

(2009) Ji-Young Kang et al.   MOLECULES AND CELLS

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Counterbalance between RB inactivation and miR-17–92 overexpression in reactive oxygen species and DNA damage induction in lung cancers

(2009) H Ebi et al.   ONCOGENE

The redox switch: dynamic regulation of protein function by cysteine modifications

(2009) Davide Spadaro et al.   PHYSIOLOGIA PLANTARUM

Glucose induces apoptosis of cardiomyocytes via microRNA-1 and IGF-1

(2008) Xi-Yong Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Foxo3a Inhibits Cardiomyocyte Hypertrophy through Transactivating Catalase

(2008) Wei-Qi Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA and cardiac pathologies

(2008) Michael V. G. Latronico et al.   PHYSIOLOGICAL GENOMICS