Receptor-interacting Protein 1 Increases Chemoresistance by Maintaining Inhibitor of Apoptosis Protein Levels and Reducing Reactive Oxygen Species through a microRNA-146a-mediated Catalase Pathway

Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIPL and IAP proteins

(2013) Lan Yang et al.   APOPTOSIS

RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species

(2013) Qiong Wang et al.   CARCINOGENESIS

The Novel SMAC Mimetic Birinapant Exhibits Potent Activity against Human Melanoma Cells

(2013) C. Krepler et al.   CLINICAL CANCER RESEARCH

Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation

(2012) Weiyang He et al.   Autophagy

ARD1 binding to RIP1 mediates doxorubicin-induced NF-κB activation

(2012) Jonggyu Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Redox modulation of the DNA damage response

(2012) Fanny Caputo et al.   BIOCHEMICAL PHARMACOLOGY

RIP1 Protein-dependent Assembly of a Cytosolic Cell Death Complex Is Required for Inhibitor of Apoptosis (IAP) Inhibitor-mediated Sensitization to Lexatumumab-induced Apoptosis

(2012) Farhan Basit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiangiogenic Agents in Combination with Chemotherapy in Patients with Advanced Non-Small Cell Lung Cancer

(2011) Susanna V. Ulahannan et al.   CANCER INVESTIGATION

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Many stimuli pull the necrotic trigger, an overview

(2011) N Vanlangenakker et al.   CELL DEATH AND DIFFERENTIATION

RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis

(2011) S Löder et al.   LEUKEMIA

A Cytosolic ATM/NEMO/RIP1 Complex Recruits TAK1 To Mediate the NF- B and p38 Mitogen-Activated Protein Kinase (MAPK)/MAPK-Activated Protein 2 Responses to DNA Damage

(2011) Y. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

(2011) Tencho Tenev et al.   MOLECULAR CELL

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Cancer cell killing via ROS: To increase or decrease, that is the question

(2010) Jie Wang et al.   CANCER BIOLOGY & THERAPY

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

(2010) Jasmin N Dynek et al.   EMBO JOURNAL

Advances in chemotherapy in advanced non-small-cell lung cancer

(2010) Paolo Maione et al.   EXPERT OPINION ON PHARMACOTHERAPY

Chemotherapy, chemoresistance and the changing treatment landscape for NSCLC

(2010) Alex Chang   LUNG CANCER

The NF-κB activation pathways, emerging molecular targets for cancer prevention and therapy

(2009) Yong Lin et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

IKK -mediated nuclear factor- B activation attenuates smac mimetic-induced apoptosis in cancer cells

(2009) L. Bai et al.   MOLECULAR CANCER THERAPEUTICS

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Mitochondrial Targeting of a Catalase Transgene Product by Plasmid Liposomes Increases RadioresistanceIn VitroandIn Vivo

(2009) Michael W. Epperly et al.   RADIATION RESEARCH

TNF-α Induces Two Distinct Caspase-8 Activation Pathways

(2008) Lai Wang et al.   CELL

Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy

(2008) Yong Lin et al.   CURRENT CANCER DRUG TARGETS

c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation

(2008) Eugene Varfolomeev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IAP-targeted therapies for cancer

(2008) E C LaCasse et al.   ONCOGENE