Suberoylanilide hydroxamic acid induces thioredoxin1-mediated apoptosis in lung cancer cells via up-regulation of miR-129-5p

MicroRNA regulation of stem cell differentiation and diseases of the bone and adipose tissue: Perspectives on miRNA biogenesis and cellular transcriptome

(2016) E.C. Martin et al.   BIOCHIMIE

Role of EMT in Metastasis and Therapy Resistance

(2016) Bethany Smith et al.   Journal of Clinical Medicine

Inhibition of thioredoxin-1 with siRNA exacerbates apoptosis by activating the ASK1-JNK/p38 pathway in brain of a stroke model rats

(2015) Xiaoying Wu et al.   BRAIN RESEARCH

Reactive oxygen species in redox cancer therapy

(2015) Lingying Tong et al.   CANCER LETTERS

Myc Induces miRNA-Mediated Apoptosis in Response to HDAC Inhibition in Hematologic Malignancies

(2015) C. M. Adams et al.   CANCER RESEARCH

MicroRNA-575 targets BLID to promote growth and invasion of non-small cell lung cancer cells

(2015) Hongwei Wang et al.   FEBS LETTERS

Antimycin A induces death of the human pulmonary fibroblast cells via ROS increase and GSH depletion

(2015) WOO HYUN PARK et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Down-Regulation of Thioredoxin1 Is Involved in Death of Calu-6 Lung Cancer Cells Treated With Suberoyl Bishydroxamic Acid

(2015) Bo Ra You et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity

(2015) K Cao et al.   ONCOGENE

Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma

(2015) Changping Li et al.   Oncotarget

DNA methylation alterations in response to prenatal exposure of maternal cigarette smoking: A persistent epigenetic impact on health from maternal lifestyle?

(2014) Christina H. Nielsen et al.   ARCHIVES OF TOXICOLOGY

Histone deacetylase inhibitors and cell death

(2014) Jing Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Activation of NADPH oxidase subunit NCF4 induces ROS-mediated EMT signaling in HeLa cells

(2014) Young Mee Kim et al.   CELLULAR SIGNALLING

Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels

(2014) BO RA YOU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1

(2014) Dengbo Ji et al.   Molecular Cancer

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reactive oxygen species, glutathione, and thioredoxin influence suberoyl bishydroxamic acid-induced apoptosis in A549 lung cancer cells

(2014) Bo Ra You et al.   TUMOR BIOLOGY

A Paradoxical Chemoresistance and Tumor Suppressive Role of Antioxidant in Solid Cancer Cells: A Strange Case of Dr. Jekyll and Mr. Hyde

(2014) Jolie Kiemlian Kwee   Biomed Research International

MicroRNA-25 functions as a potential tumor suppressor in colon cancer by targeting Smad7

(2013) Qiang Li et al.   CANCER LETTERS

Dual Role of the Antioxidant Enzyme Peroxiredoxin 6 in Skin Carcinogenesis

(2013) F. Rolfs et al.   CANCER RESEARCH

RNH1 regulation of reactive oxygen species contributes to histone deacetylase inhibitor resistance in gastric cancer cells

(2013) Y Zhu et al.   ONCOGENE

MAPK inhibitors augment gallic acid-induced A549 lung cancer cell death through the enhancement of glutathione depletion

(2013) WOO HYUN PARK et al.   ONCOLOGY REPORTS

miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer

(2013) M Karaayvaz et al.   Cell Death & Disease

Cycling hypoxia up-regulates thioredoxin levels in human MDA-MB-231 breast cancer cells

(2012) Therese C. Karlenius et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A unique histone deacetylase inhibitor alters microRNA expression and signal transduction in chemoresistant ovarian cancer cells

(2012) Curt Balch et al.   CANCER BIOLOGY & THERAPY

Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells

(2012) Yoshihide Shimojo et al.   CLINICAL & EXPERIMENTAL METASTASIS

Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy

(2011) Min-Yu Chen et al.   CANCER

MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells

(2011) Patrick Brest et al.   ENDOCRINE-RELATED CANCER

Disruption of redox homeostasis and induction of apoptosis by suppression of glutathione synthetase expression in a mammalian cell line

(2011) Su-Jung Kim et al.   FREE RADICAL RESEARCH

Cellular Iron Depletion Stimulates the JNK and p38 MAPK Signaling Transduction Pathways, Dissociation of ASK1-Thioredoxin, and Activation of ASK1

(2011) Yu Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidant Potential of Glutathione: A Theoretical Study

(2011) Béla Fiser et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Stay Tuned: miRNA Expression and Nonsense-Mediated Decay in Brain Development

(2011) Andreas E. Kulozik   MOLECULAR CELL

Structure, Function, and Mechanism of Thioredoxin Proteins

(2010) Jean-Francois Collet et al.   ANTIOXIDANTS & REDOX SIGNALING

Suberoylanilide hydroxamic acid limits migration and invasion of glioma cells in two and three dimensional culture

(2010) Zhihua An et al.   CANCER LETTERS

miR-129 regulates cell proliferation by downregulating Cdk6 expression

(2010) Junjie Wu et al.   CELL CYCLE

Oxidative stress-induced antioxidant enzyme expression is an early phenomenon in ovarian carcinogenesis

(2010) Marjo Pylväs et al.   EUROPEAN JOURNAL OF CANCER

Inhibition of histone deacetylase 10 induces thioredoxin-interacting protein and causes accumulation of reactive oxygen species in SNU-620 human gastric cancer cells

(2010) Ju-Hee Lee et al.   MOLECULES AND CELLS

High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo

(2009) Annika Lehmann et al.   BMC CANCER

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Epigenetic Profiles Distinguish Pleural Mesothelioma from Normal Pleura and Predict Lung Asbestos Burden and Clinical Outcome

(2008) B. C. Christensen et al.   CANCER RESEARCH

Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer

(2007) Terumasa Noike et al.   HUMAN PATHOLOGY