Bioinformatic analysis reveals an evolutional selection for DNA:RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals

MotifLab: a tools and data integration workbench for motif discovery and regulatory sequence analysis

(2013) Kjetil Klepper et al.   BMC BIOINFORMATICS

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control

(2013) Ke-wei Zheng et al.   NUCLEIC ACIDS RESEARCH

Up-Regulating Relaxin Expression by G-Quadruplex Interactive Ligand to Achieve Antifibrotic Action

(2012) Hui-Ping Gu et al.   ENDOCRINOLOGY

Discovery of novel rules for G-quadruplex-forming sequences in plants by using bioinformatics methods

(2012) Hiro Takahashi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

QGRS-H Predictor: a web server for predicting homologous quadruplex forming G-rich sequence motifs in nucleotide sequences

(2012) Camille Menendez et al.   NUCLEIC ACIDS RESEARCH

5'-UTR RNA G-quadruplexes: translation regulation and targeting

(2012) A. Bugaut et al.   NUCLEIC ACIDS RESEARCH

Formation, recognition and bioactivities of a novel G-quadruplex in the STAT3 gene

(2011) Sen Lin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast

(2011) Nayun Kim et al.   DNA REPAIR

R-loop-mediated genomic instability is caused by impairment of replication fork progression

(2011) W. Gan et al.   GENES & DEVELOPMENT

G-Quadruplex-Binding Benzo[a]phenoxazines Down-Regulatec-KITExpression in Human Gastric Carcinoma Cells

(2011) Keith I. E. McLuckie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

DNA secondary structures and epigenetic determinants of cancer genome evolution

(2011) Subhajyoti De et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase

(2011) Q. Wang et al.   NUCLEIC ACIDS RESEARCH

G4 motifs correlate with promoter-proximal transcriptional pausing in human genes

(2011) J. Eddy et al.   NUCLEIC ACIDS RESEARCH

Mapping the sequences of potential guanine quadruplex motifs

(2011) Alan K. Todd et al.   NUCLEIC ACIDS RESEARCH

Making sense of G-quadruplex and i-motif functions in oncogene promoters

(2010) Tracy A. Brooks et al.   FEBS Journal

Structure, location and interactions of G-quadruplexes

(2010) Julian L. Huppert   FEBS Journal

Turning off Transcription of thebcl-2Gene by Stabilizing thebcl-2Promoter Quadruplex with Quindoline Derivatives

(2010) Xiao-Dong Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

G-Quadruplex Hinders Translocation of BLM Helicase on DNA: A Real-Time Fluorescence Spectroscopic Unwinding Study and Comparison with Duplex Substrates

(2010) Jia-quan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Guanine quadruplex DNA structure restricts methylation of CpG dinucleotides genome-wide

(2010) Rashi Halder et al.   Molecular BioSystems

Inducement of G-Quadruplex DNA Forming and Down-Regulation of OncogeneC-MYCby Bile Acid-Amino Acid Conjugate—BAA

(2010) Mingyue Tian et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Mechanisms and implications of transcription blockage by guanine-rich DNA sequences

(2010) B. P. Belotserkovskii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer

(2009) Stephen Neidle   FEBS Journal

CpG islands - ‘A rough guide’

(2009) Robert S. Illingworth et al.   FEBS LETTERS

Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNA

(2009) Ke-wei Zheng et al.   NUCLEIC ACIDS RESEARCH

Genome-wide colonization of gene regulatory elements by G4 DNA motifs

(2009) Zhuo Du et al.   NUCLEIC ACIDS RESEARCH

Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells

(2009) Anjali Verma et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex structures: in vivo evidence and function

(2009) Hans J. Lipps et al.   TRENDS IN CELL BIOLOGY

Mechanism and Regulation of Class Switch Recombination

(2008) Janet Stavnezer et al.   Annual Review of Immunology

G4-forming Sequences in the Non-transcribed DNA Strand Pose Blocks to T7 RNA Polymerase and Mammalian RNA Polymerase II

(2008) Silvia Tornaletti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-Wide Computational and Expression Analyses Reveal G-Quadruplex DNA Motifs as Conservedcis-Regulatory Elements in Human and Related Species

(2008) Anjali Verma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes

(2008) Johanna Eddy et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes: the beginning and end of UTRs

(2008) Julian Leon Huppert et al.   NUCLEIC ACIDS RESEARCH

Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription

(2007) Z. Du et al.   GENOME RESEARCH