Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis
Authors
Keywords
-
Journal
EMBO Molecular Medicine
Volume 12, Issue 8, Pages -
Publisher
EMBO
Online
2020-06-29
DOI
10.15252/emmm.202012034
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Increased monocyte count as a cellular biomarker for poor outcomes in fibrotic diseases: a retrospective, multicentre cohort study
- (2019) Madeleine K D Scott et al. Lancet Respiratory Medicine
- Macrophages: versatile players in renal inflammation and fibrosis
- (2019) Patrick Ming-Kuen Tang et al. Nature Reviews Nephrology
- Clinical Effectiveness of Antifibrotic Medications for Idiopathic Pulmonary Fibrosis
- (2019) Timothy M. Dempsey et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies
- (2019) Stefanie R. Mullins et al. Journal for ImmunoTherapy of Cancer
- The therapy of idiopathic pulmonary fibrosis: what is next?
- (2019) Vivien Somogyi et al. European Respiratory Review
- Differences in TLR7/8 activation between monocytes and macrophages
- (2018) Hock-Liew Eng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The big five in fibrosis: Macrophages, myofibroblasts, matrix, mechanics, and miscommunication
- (2018) Pardis Pakshir et al. MATRIX BIOLOGY
- TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy
- (2018) Christopher B. Rodell et al. Nature Biomedical Engineering
- Evaluation of Novel Tumor-Targeted Near-Infrared Probe for Fluorescence-Guided Surgery of Cancer
- (2018) Sakkarapalayam M. Mahalingam et al. JOURNAL OF MEDICINAL CHEMISTRY
- Looking ahead and behind at supplemental oxygen: A qualitative study of patients with pulmonary fibrosis
- (2017) Bridget A. Graney et al. HEART & LUNG
- IRAK4 kinase activity controls Toll-like receptor–induced inflammation through the transcription factor IRF5 in primary human monocytes
- (2017) Leah Cushing et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span
- (2017) Alexander V. Misharin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Toll for Trafficking: Toll-Like Receptor 7 Delivery to the Endosome
- (2017) Carlene Petes et al. Frontiers in Immunology
- Macrophages in Tissue Repair, Regeneration, and Fibrosis
- (2016) Thomas A. Wynn et al. IMMUNITY
- Monocyte and macrophage contributions to cardiac remodeling
- (2016) Maarten Hulsmans et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Strategies to overcome the hurdles to treat fibrosis, a major unmet clinical need
- (2016) Jagdeep Nanchahal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pulmonary Macrophages: A New Therapeutic Pathway in Fibrosing Lung Disease?
- (2016) Adam J. Byrne et al. TRENDS IN MOLECULAR MEDICINE
- Arginase inhibition prevents bleomycin-induced pulmonary hypertension, vascular remodeling, and collagen deposition in neonatal rat lungs
- (2015) Hartmut Grasemann et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide
- (2015) Marie Genin et al. BMC CANCER
- Principles in the design of ligand-targeted cancer therapeutics and imaging agents
- (2015) Madduri Srinivasarao et al. NATURE REVIEWS DRUG DISCOVERY
- Pulmonary macrophages: key players in the innate defence of the airways
- (2015) Adam J Byrne et al. THORAX
- Macrophages During the Fibrotic Process: M2 as Friend and Foe
- (2015) Tarcio Teodoro Braga et al. Frontiers in Immunology
- Folate Receptor-β in Activated Macrophages: Ligand Binding and Receptor Recycling Kinetics
- (2014) Bindu Varghese et al. MOLECULAR PHARMACEUTICS
- Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis
- (2014) Luca Richeldi et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Pro-Inflammatory Cytokine, Interleukin-6, Enhances the Polarization of Alternatively Activated Macrophages
- (2014) Maria Ruweka Fernando et al. PLoS One
- Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage
- (2013) Thian Kui Tan et al. LABORATORY INVESTIGATION
- Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis
- (2013) Yoony YJ Gent et al. ARTHRITIS RESEARCH & THERAPY
- Biological characterization of a novel class of toll-like receptor 7 agonists designed to have reduced systemic activity
- (2011) M Biffen et al. BRITISH JOURNAL OF PHARMACOLOGY
- Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials
- (2011) Paul W Noble et al. LANCET
- A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity
- (2011) Yang Feng et al. ARTHRITIS RESEARCH & THERAPY
- Toll-like receptor-7 agonist administered subcutaneously in a prolonged dosing schedule in heavily pretreated recurrent breast, ovarian, and cervix cancers
- (2010) Melissa A. Geller et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Effect of an immunotoxin to folate receptor β on bleomycin-induced experimental pulmonary fibrosis
- (2010) T. Nagai et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent
- (2010) Mark S. Wilson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Structure−Activity Relationships in Human Toll-Like Receptor 7-Active Imidazoquinoline Analogues
- (2010) Nikunj M. Shukla et al. JOURNAL OF MEDICINAL CHEMISTRY
- Low-dose oral interferon possibly retards the progression of idiopathic pulmonary fibrosis and alleviates associated cough in some patients
- (2010) L. O. Lutherer et al. THORAX
- Folate Receptor Is Expressed by Tumor-Associated Macrophages and Constitutes a Marker for M2 Anti-inflammatory/Regulatory Macrophages
- (2009) A. Puig-Kroger et al. CANCER RESEARCH
- Folate-targeted therapeutic and imaging agents for cancer
- (2009) Philip Stewart Low et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages
- (2008) W. Xia et al. BLOOD
- Discovery and Development of Folic-Acid-Based Receptor Targeting for Imaging and Therapy of Cancer and Inflammatory Diseases
- (2007) Philip S. Low et al. ACCOUNTS OF CHEMICAL RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started