Macrophages: versatile players in renal inflammation and fibrosis

Myeloid-derived Suppressor Cells Are Necessary for Development of Pulmonary Hypertension

(2018) Andrew J. Bryant et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Ca 2+ signaling and Src-kinases-controlled cellular functions

(2018) Estefanía Anguita et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The multifaceted role of the renal mononuclear phagocyte system

(2018) Susanne F. Viehmann et al.   CELLULAR IMMUNOLOGY

Myeloid cell heterogeneity in cancer: not a single cell alike

(2018) Mate Kiss et al.   CELLULAR IMMUNOLOGY

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine AtherosclerosisNovelty and Significance

(2018) Clément Cochain et al.   CIRCULATION RESEARCH

CX3CL1/CX3CR1 Axis, as the Therapeutic Potential in Renal Diseases: Friend or Foe?

(2018) Quan Zhuang et al.   CURRENT GENE THERAPY

Galectin-3 is independently associated with progression of nephropathy in type 2 diabetes mellitus

(2018) Kathryn C. B. Tan et al.   DIABETOLOGIA

Transforming growth factor-β signalling in renal fibrosis: from Smads to non-coding RNAs

(2018) Patrick Ming-Kuen Tang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD

(2018) Takanori Komada et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cellular Origin and Functional Relevance of Collagen I Production in the Kidney

(2018) Simone Buchtler et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory Response

(2018) Haojia Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The myeloid mineralocorticoid receptor controls inflammatory and fibrotic responses after renal injury via macrophage interleukin-4 receptor signaling

(2018) Jonatan Barrera-Chimal et al.   KIDNEY INTERNATIONAL

The macrophage phenotype and inflammasome component NLRP3 contributes to nephrocalcinosis-related chronic kidney disease independent from IL-1–mediated tissue injury

(2018) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

The proto-oncogene tyrosine protein kinase Src is essential for macrophage-myofibroblast transition during renal scarring

(2018) Patrick Ming-Kuen Tang et al.   KIDNEY INTERNATIONAL

Matrix metalloproteinase-12 deficiency attenuates experimental crescentic anti-glomerular basement membrane glomerulonephritis

(2018) Abu P. Abraham et al.   NEPHROLOGY

JAK1/JAK2 inhibition by baricitinib in diabetic kidney disease: results from a Phase 2 randomized controlled clinical trial

(2018) Katherine R Tuttle et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney

(2018) Amrutesh S. Puranik et al.   Scientific Reports

Human macrophage ferroportin biology and the basis for the ferroportin disease

(2017) Manuela Sabelli et al.   HEPATOLOGY

CCR2+ monocytic myeloid-derived suppressor cells (M-MDSCs) inhibit collagen degradation and promote lung fibrosis by producing transforming growth factor-β1

(2017) Astrid Lebrun et al.   JOURNAL OF PATHOLOGY

Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury

(2017) Ying-Ying Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Wnt/ β -Catenin–Promoted Macrophage Alternative Activation Contributes to Kidney Fibrosis

(2017) Ye Feng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Macrophage density in early surveillance biopsies predicts future renal transplant function

(2017) Jan Hinrich Bräsen et al.   KIDNEY INTERNATIONAL

The pattern recognition receptor, Mincle, is essential for maintaining the M1 macrophage phenotype in acute renal inflammation

(2017) Lin L. Lv et al.   KIDNEY INTERNATIONAL

The IL-4 receptor α has a critical role in bone marrow–derived fibroblast activation and renal fibrosis

(2017) Hua Liang et al.   KIDNEY INTERNATIONAL

IL-4/IL-13–mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury

(2017) Ming-Zhi Zhang et al.   KIDNEY INTERNATIONAL

Parabiosis reveals leukocyte dynamics in the kidney

(2017) Jeremie M Lever et al.   LABORATORY INVESTIGATION

Targeting the tyrosine kinase signalling pathways for treatment of immune-mediated glomerulonephritis: from bench to bedside and beyond

(2017) Terry King-Wing Ma et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

M2A and M2C Macrophage Subsets Ameliorate Inflammation and Fibroproliferation in Acute Lung Injury Through Interleukin 10 Pathway

(2017) Lunxian Tang et al.   SHOCK

Inhibition of Spleen Tyrosine Kinase Reduces Renal Allograft Injury in a Rat Model of Acute Antibody-Mediated Rejection in Sensitized Recipients

(2017) Sharmila Ramessur Chandran et al.   TRANSPLANTATION

Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection

(2017) Shomyseh Sanjabi et al.   Cold Spring Harbor Perspectives in Biology

CSF-1R Inhibitor Development: Current Clinical Status

(2017) Florent Peyraud et al.   Current Oncology Reports

The JNK Signaling Pathway in Renal Fibrosis

(2017) Keren Grynberg et al.   Frontiers in Physiology

Spleen Tyrosine Kinase Signaling Promotes Myeloid Cell Recruitment and Kidney Damage after Renal Ischemia/Reperfusion Injury

(2016) Jessica Ryan et al.   AMERICAN JOURNAL OF PATHOLOGY

CXCL16 regulates renal injury and fibrosis in experimental renal artery stenosis

(2016) Zhiheng Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Design Strategies, Structures and Molecular Interactions of Small Molecule Src Inhibitors

(2016) Sureyya Olgen   Anti-Cancer Agents in Medicinal Chemistry

Monocyte chemoattractant protein-1 and the kidney

(2016) Hermann Haller et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Curcumin alleviates renal dysfunction and suppresses inflammation by shifting from M1 to M2 macrophage polarization in daunorubicin induced nephrotoxicity in rats

(2016) Vengadeshprabhu Karuppagounder et al.   CYTOKINE

JAK inhibition in the treatment of diabetic kidney disease

(2016) Frank C. Brosius et al.   DIABETOLOGIA

The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells

(2016) Shinelle Menezes et al.   IMMUNITY

TNFα-induced M-MDSCs promote transplant immune tolerance via nitric oxide

(2016) Fan Yang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Brain trauma elicits non-canonical macrophage activation states

(2016) Charles C. Kim et al.   Journal of Neuroinflammation

Genomic Analysis of Kidney Allograft Injury Identifies Hematopoietic Cell Kinase as a Key Driver of Renal Fibrosis

(2016) Chengguo Wei et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis

(2016) Yanli Yan et al.   KIDNEY INTERNATIONAL

A role for spleen tyrosine kinase in renal fibrosis in the mouse obstructed kidney

(2016) Frank Y. Ma et al.   LIFE SCIENCES

Intrarenal macrophage infiltration induced by T cells is associated with podocyte injury in lupus nephritis patients

(2016) R Ma et al.   LUPUS

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

M1 polarization and the effect of PGE2on TNF-α production by lymph node cells from dogs with visceral leishmaniasis

(2016) G. L. Venturin et al.   PARASITE IMMUNOLOGY

The Macrophage Phagocytic Receptor CD36 Promotes Fibrogenic Pathways on Removal of Apoptotic Cells during Chronic Kidney Injury

(2015) Subramaniam Pennathur et al.   AMERICAN JOURNAL OF PATHOLOGY

Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration

(2015) Amitava Das et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of Renal Fibrosis by Macrophage Polarization

(2015) Bixia Pan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

JAK inhibition and progressive kidney disease

(2015) Frank C. Brosius et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Vibrio cholerae porin OmpU mediates M1-polarization of macrophages/monocytes via TLR1/TLR2 activation

(2015) Junaid Khan et al.   IMMUNOBIOLOGY

Cigarette smoke extract–treated mast cells promote alveolar macrophage infiltration and polarization in experimental chronic obstructive pulmonary disease

(2015) Hong Li et al.   INHALATION TOXICOLOGY

CX3CL1–CX3CR1 Interaction Increases the Population of Ly6C−CX3CR1hiMacrophages Contributing to Unilateral Ureteral Obstruction–Induced Fibrosis

(2015) Xiaogang Peng et al.   JOURNAL OF IMMUNOLOGY

Myeloid cell-mediated renal injury in rapidly progressive glomerulonephritis depends upon spleen tyrosine kinase

(2015) Jessica Ryan et al.   JOURNAL OF PATHOLOGY

Differential Ly6C Expression after Renal Ischemia-Reperfusion Identifies Unique Macrophage Populations

(2015) M. Clements et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Anti-Inflammatory Role of MicroRNA-146a in the Pathogenesis of Diabetic Nephropathy

(2015) K. Bhatt et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

JAK3/STAT6 Stimulates Bone Marrow-Derived Fibroblast Activation in Renal Fibrosis

(2015) J. Yan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Macrophage-derived tumor necrosis factor-α mediates diabetic renal injury

(2015) Alaa S. Awad et al.   KIDNEY INTERNATIONAL

Correlation of disease activity in proliferative glomerulonephritis with glomerular spleen tyrosine kinase expression

(2015) Stephen P. McAdoo et al.   KIDNEY INTERNATIONAL

Diverse origins of the myofibroblast—implications for kidney fibrosis

(2015) Lucas L. Falke et al.   Nature Reviews Nephrology

Fibrosis — A Common Pathway to Organ Injury and Failure

(2015) Don C. Rockey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Present and Future in the Treatment of Diabetic Kidney Disease

(2015) Borja Quiroga et al.   Journal of Diabetes Research

The effect of CCR2 inhibitor CCX140-B on residual albuminuria in patients with type 2 diabetes and nephropathy: a randomised trial

(2015) Dick de Zeeuw et al.   Lancet Diabetes & Endocrinology

Macrophage Polarization In The Tumor Microenvironment

(2015) Bernhard Brüne et al.   Redox Biology

Horizon 2020 in Diabetic Kidney Disease: The Clinical Trial Pipeline for Add-On Therapies on Top of Renin Angiotensin System Blockade

(2015) Maria Perez-Gomez et al.   Journal of Clinical Medicine

Differential Induction of Ly6G and Ly6C Positive Myeloid Derived Suppressor Cells in Chronic Kidney and Liver Inflammation and Fibrosis

(2015) Bastian Höchst et al.   PLoS One

The Role of Macrophages in the Development of Human Renal Allograft Fibrosis in the First Year After Transplantation

(2014) D. Toki et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Proinflammatory-Activated Glioma Cells Induce a Switch in Microglial Polarization and Activation Status, From a Predominant M2b Phenotype to a Mixture of M1 and M2a/B Polarized Cells

(2014) Lucia Lisi et al.   ASN Neuro

The role of macrophage phenotype in vascularization of tissue engineering scaffolds

(2014) Kara L. Spiller et al.   BIOMATERIALS

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Contrasting Effects of Systemic Monocyte/Macrophage and CD4+T Cell Depletion in a Reversible Ureteral Obstruction Mouse Model of Chronic Kidney Disease

(2014) Lee D. Chaves et al.   Clinical & Developmental Immunology

Vitamin D Prevents Podocyte Injury via Regulation of Macrophage M1/M2 Phenotype in Diabetic Nephropathy Rats

(2014) Xiao-Liang Zhang et al.   ENDOCRINOLOGY

Macrophages Regulate Renal Fibrosis Through Modulating TGFβ Superfamily Signaling

(2014) Bing Shen et al.   INFLAMMATION

Specific Macrophage Subtypes Influence the Progression of Rhabdomyolysis-Induced Kidney Injury

(2014) J. Belliere et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Spleen Tyrosine Kinase Inhibition Attenuates Autoantibody Production and Reverses Experimental Autoimmune GN

(2014) S. P. McAdoo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Myeloid Mineralocorticoid Receptor Activation Contributes to Progressive Kidney Disease

(2014) L. L. Huang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Smad3 signaling activates bone marrow-derived fibroblasts in renal fibrosis

(2014) Jiyuan Chen et al.   LABORATORY INVESTIGATION

Dendritic cells and macrophages in the kidney: a spectrum of good and evil

(2014) Natasha M. Rogers et al.   Nature Reviews Nephrology

Macrophage-mediated injury and repair after ischemic kidney injury

(2014) Sarah C. Huen et al.   PEDIATRIC NEPHROLOGY

Alternatively activated macrophages in the pathogenesis of chronic kidney allograft injury

(2014) Yohei Ikezumi et al.   PEDIATRIC NEPHROLOGY

An optimized Protocol for Human M2 Macrophages using M-CSF and IL-4/IL-10/TGF-βYields a Dominant Immunosuppressive Phenotype

(2014) S. Mia et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Macrophages promote renal fibrosis through direct and indirect mechanisms

(2014) David J. Nikolic-Paterson et al.   Kidney International Supplements

The FOXD1 lineage of kidney perivascular cells and myofibroblasts: functions and responses to injury

(2014) Ivan G. Gomez et al.   Kidney International Supplements

Monocytic Myeloid-Derived Suppressor Cells Accumulate in Renal Transplant Patients and Mediate CD4+Foxp3+Treg Expansion

(2013) Y. Luan et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Bone marrow-derived cells play a major role in kidney fibrosis via proliferation and differentiation in the infiltrated site

(2013) Hee-Seong Jang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

A critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and functionin vitroandin vivo

(2013) Christina E. Arnold et al.   IMMUNOLOGY

Macrophage Phenotype Controls Long-Term AKI Outcomes--Kidney Regeneration versus Atrophy

(2013) M. Lech et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Plasticity of Renal Erythropoietin-Producing Cells Governs Fibrosis

(2013) T. Souma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model

(2013) Barbara Reich et al.   KIDNEY INTERNATIONAL

Discrete functions of M 2a and M 2c macrophage subsets determine their relative efficacy in treating chronic kidney disease

(2013) Junyu Lu et al.   KIDNEY INTERNATIONAL

Failed renoprotection by alternatively activated bone marrow macrophages is due to a proliferation-dependent phenotype switch in vivo

(2013) Qi Cao et al.   KIDNEY INTERNATIONAL

Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage

(2013) Thian Kui Tan et al.   LABORATORY INVESTIGATION

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(2013) Tarcio Braga et al.   MOLECULAR MEDICINE

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Macrophages Contribute to Cellular But Not Humoral Mechanisms of Acute Rejection in Rat Renal Allografts

(2013) Frank Y. Ma et al.   TRANSPLANTATION

Inflammatory macrophage phenotype in BTBR T+tf/J mice

(2013) Charity E. Onore et al.   Frontiers in Neuroscience

CD4+ T Lymphocytes, Especially Th2 Cells, Contribute to the Progress of Renal Fibrosis

(2012) Lili Liu et al.   AMERICAN JOURNAL OF NEPHROLOGY

Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathy

(2012) Eoin P. Brennan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

TGFβ signaling plays a critical role in promoting alternative macrophage activation

(2012) Dapeng Gong et al.   BMC IMMUNOLOGY

Macrophage Mineralocorticoid Receptor Signaling Plays a Key Role in Aldosterone-Independent Cardiac Fibrosis

(2012) Laura A. Bienvenu et al.   ENDOCRINOLOGY

Role of interplay between IL-4 and IFN-γ in the in regulating M1 macrophage polarization induced by Nattectin

(2012) Edson Kiyotaka Ishizuka et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CSF-1 signaling mediates recovery from acute kidney injury

(2012) Ming-Zhi Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis

(2012) Marc Weidenbusch et al.   Journal of Innate Immunity

Reduced Il17a Expression Distinguishes a Ly6c lo MHCII hi Macrophage Population Promoting Wound Healing

(2012) Mathieu P. Rodero et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Resolvins E1 and D1 inhibit interstitial fibrosis in the obstructed kidney via inhibition of local fibroblast proliferation

(2012) Xinli Qu et al.   JOURNAL OF PATHOLOGY

The myofibroblast matrix: implications for tissue repair and fibrosis

(2012) Franco Klingberg et al.   JOURNAL OF PATHOLOGY

Distinct sites of renal fibrosis inCrim1mutant mice arise from multiple cellular origins

(2012) Yu Leng Phua et al.   JOURNAL OF PATHOLOGY

Fc  Receptor Deficiency Attenuates Diabetic Nephropathy

(2012) V. Lopez-Parra et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H–deficient mice

(2012) Jessy J. Alexander et al.   KIDNEY INTERNATIONAL

Macrophage/monocyte depletion by clodronate, but not diphtheria toxin, improves renal ischemia/reperfusion injury in mice

(2012) David A. Ferenbach et al.   KIDNEY INTERNATIONAL

Involvement of matrix metalloproteinase-2 in the development of renal interstitial fibrosis in mouse obstructive nephropathy

(2012) Xuanyi Du et al.   LABORATORY INVESTIGATION

Colony-Stimulating Factor-1 Promotes Kidney Growth and Repair via Alteration of Macrophage Responses

(2011) Maliha A. Alikhan et al.   AMERICAN JOURNAL OF PATHOLOGY

C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes

(2011) F. Liu et al.   DIABETOLOGIA

Identification of alternatively activated macrophages in new-onset paediatric and adult immunoglobulin A nephropathy: potential role in mesangial matrix expansion

(2011) Yohei Ikezumi et al.   HISTOPATHOLOGY

Dangers Within: DAMP Responses to Damage and Cell Death in Kidney Disease

(2011) D. L. Rosin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CXCL16 Recruits Bone Marrow-Derived Fibroblast Precursors in Renal Fibrosis

(2011) G. Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis

(2011) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

Platelet-derived growth factor receptor signaling activates pericyte–myofibroblast transition in obstructive and post-ischemic kidney fibrosis

(2011) Yi-Ting Chen et al.   KIDNEY INTERNATIONAL

c-fms blockade reverses glomerular macrophage infiltration and halts development of crescentic anti-GBM glomerulonephritis in the rat

(2011) Yingjie Han et al.   LABORATORY INVESTIGATION

C-reactive protein promotes acute renal inflammation and fibrosis in unilateral ureteral obstructive nephropathy in mice

(2011) Zi Li et al.   LABORATORY INVESTIGATION

Alternative activation of macrophages in human peritoneum: implications for peritoneal fibrosis

(2011) Teresa Bellón et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Contrasting Effects of Steroids and Mizoribine on Macrophage Activation and Glomerular Lesions in Rat Thy-1 Mesangial Proliferative Glomerulonephritis

(2010) Yohei Ikezumi et al.   AMERICAN JOURNAL OF NEPHROLOGY

Macrophage Matrix Metalloproteinase-9 Mediates Epithelial-Mesenchymal Transition in Vitro in Murine Renal Tubular Cells

(2010) Thian Kui Tan et al.   AMERICAN JOURNAL OF PATHOLOGY

Fibrocytes in health and disease

(2010) Erica L. Herzog et al.   EXPERIMENTAL HEMATOLOGY

Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice

(2010) Mercedes Rodriguez Garcia et al.   JOURNAL OF CLINICAL INVESTIGATION

HMGB1 Contributes to Kidney Ischemia Reperfusion Injury

(2010) H. Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CCR2 antagonism improves insulin resistance, lipid metabolism, and diabetic nephropathy in type 2 diabetic mice

(2010) Young Sun Kang et al.   KIDNEY INTERNATIONAL

Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-α-mediated podocyte loss

(2010) Mi Ryu et al.   KIDNEY INTERNATIONAL

Alteration in the phenotype of macrophages in the repair of renal interstitial fibrosis in mice

(2010) TAKETOSHI KUSHIYAMA et al.   NEPHROLOGY

JNK signalling in human and experimental renal ischaemia/reperfusion injury

(2010) J. Kanellis et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Endothelial-Myofibroblast Transition Contributes to the Early Development of Diabetic Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice

(2009) Jinhua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice

(2009) A. K. H. Lim et al.   DIABETOLOGIA

Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model

(2009) Mizuho Tamura et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Deletion of Mineralocorticoid Receptors From Macrophages Protects Against Deoxycorticosterone/Salt-Induced Cardiac Fibrosis and Increased Blood Pressure

(2009) Amanda J. Rickard et al.   HYPERTENSION

Bone Marrow Ly6Chigh Monocytes Are Selectively Recruited to Injured Kidney and Differentiate into Functionally Distinct Populations

(2009) S. L. Lin et al.   JOURNAL OF IMMUNOLOGY

M1 and M2a Polarization of Human Monocyte-Derived Macrophages Inhibits HIV-1 Replication by Distinct Mechanisms

(2009) Edana Cassol et al.   JOURNAL OF IMMUNOLOGY

Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat

(2009) Frank Y Ma et al.   LABORATORY INVESTIGATION

IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis

(2009) Lynelle K. Jones et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

(2008) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Galectin-3 Expression and Secretion Links Macrophages to the Promotion of Renal Fibrosis

(2008) Neil C. Henderson et al.   AMERICAN JOURNAL OF PATHOLOGY

An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus

(2008) Frances Rena Bahjat et al.   ARTHRITIS AND RHEUMATISM

Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis

(2008) Catherine Skhirtladze et al.   ARTHRITIS AND RHEUMATISM

Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

(2008) C. C. Berthier et al.   DIABETES

Azithromycin alters macrophage phenotype

(2008) B. S. Murphy et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

PDGF-C Is a Proinflammatory Cytokine that Mediates Renal Interstitial Fibrosis

(2008) F. Eitner et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

(2008) E. M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia–reperfusion injury

(2008) Li Li et al.   KIDNEY INTERNATIONAL