Helicobacter pylori Avoids the Critical Activation of NLRP3 Inflammasome-Mediated Production of Oncogenic Mature IL-1β in Human Immune Cells

The Relationship between Toll-like Receptors and Helicobacter pylori-Related Gastropathies: Still a Controversial Topic

(2019) Lorena Elena Meliț et al.   Journal of Immunology Research

Campylobacter jejuni enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA

(2019) Aileen Harrer et al.   Gut Pathogens

Novel Insights of Lymphomagenesis of Helicobacter pylori-Dependent Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

(2019) Sung-Hsin Kuo et al.   Cancers

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations

(2019) Anna Zawilak-Pawlik et al.   Scientific Reports

Spatial orchestration of mitochondrial translation and OXPHOS complex assembly

(2018) Stefan Stoldt et al.   NATURE CELL BIOLOGY

Epidemiology of Helicobacter pylori infection

(2018) Olga Sjomina et al.   HELICOBACTER

Interleukin-1 Beta—A Friend or Foe in Malignancies?

(2018) Rebekka Bent et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation

(2018) Jueqi Chen et al.   NATURE

Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis

(2017) James K.Y. Hooi et al.   GASTROENTEROLOGY

IL-1 and IL-1 regulatory pathways in cancer progression and therapy

(2017) Alberto Mantovani et al.   IMMUNOLOGICAL REVIEWS

Helicobacter pylori controls NLRP3 expression by regulating hsa-miR-223-3p and IL-10 in cultured and primary human immune cells

(2017) Suneesh Kumar Pachathundikandi et al.   Innate Immunity

Helicobacter pylori infection is associated with an altered gastric microbiota in children

(2017) K M Brawner et al.   Mucosal Immunology

NLRP3 Controls the Development of Gastrointestinal CD11b + Dendritic Cells in the Steady State and during Chronic Bacterial Infection

(2017) Isabelle C. Arnold et al.   Cell Reports

Helicobacter pylori induces IL-1β protein through the inflammasome activation in differentiated macrophagic cells

(2016) Shoichiro KAMEOKA et al.   BIOMEDICAL RESEARCH-TOKYO

Pathogenesis ofHelicobacter pyloriinfection

(2016) Steffen Backert et al.   HELICOBACTER

Helicobacter pylori Infection Synergistic with IL-1β Gene Polymorphisms Potentially Contributes to the Carcinogenesis of Gastric Cancer

(2016) Jun-Bo Hong et al.   International Journal of Medical Sciences

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22

(2016) Marianne R. Spalinger et al.   JOURNAL OF CLINICAL INVESTIGATION

TRPM2 ion channels regulate macrophage polarization and gastric inflammation during Helicobacter pylori infection

(2016) S Beceiro et al.   Mucosal Immunology

NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations

(2016) Leanne Mortimer et al.   NATURE IMMUNOLOGY

NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β–mediated osteomyelitis

(2016) Prajwal Gurung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Immune Battle against Helicobacter pylori Infection: NO Offense

(2016) Alain P. Gobert et al.   TRENDS IN MICROBIOLOGY

An Overview of Helicobacter pylori VacA Toxin Biology

(2016) Nora Foegeding et al.   Toxins

Helicobacter pylori-Mediated Protection from Allergy Is Associated with IL-10-Secreting Peripheral Blood Regulatory T Cells

(2016) Khiyam Hussain et al.   Frontiers in Immunology

Performance benchmarking of four cell-free protein expression systems

(2015) Dejan Gagoski et al.   BIOTECHNOLOGY AND BIOENGINEERING

Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells

(2015) Jonathan L. Schmid-Burgk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-1B signalling leads to increased survival of gastric carcinoma cells through a CREB-C/EBPβ-associated mechanism

(2015) Carlos Resende et al.   Gastric Cancer

The MUC1 mucin protects againstHelicobacter pyloripathogenesis in mice by regulation of the NLRP3 inflammasome

(2015) Garrett Z Ng et al.   GUT

Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme

(2015) Inna S. Afonina et al.   IMMUNITY

Helicobacter urease–induced activation of the TLR2/NLRP3/IL-18 axis protects against asthma

(2015) Katrin N. Koch et al.   JOURNAL OF CLINICAL INVESTIGATION

InternalizedCryptococcus neoformansActivates the Canonical Caspase-1 and the Noncanonical Caspase-8 Inflammasomes

(2015) Mingkuan Chen et al.   JOURNAL OF IMMUNOLOGY

Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular

(2015) Jason H. Melehani et al.   PLoS Pathogens

Interplay of the Gastric PathogenHelicobacter pyloriwith Toll-Like Receptors

(2015) Suneesh Kumar Pachathundikandi et al.   Biomed Research International

Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation

(2015) Prajwal Gurung et al.   Scientific Reports

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Helicobacter pylori–Induced IL-1β Secretion in Innate Immune Cells Is Regulated by the NLRP3 Inflammasome and Requires the Cag Pathogenicity Island

(2014) Raphaela P. Semper et al.   JOURNAL OF IMMUNOLOGY

Heme Oxygenase-1 Dysregulates Macrophage Polarization and the Immune Response toHelicobacter pylori

(2014) Alain P. Gobert et al.   JOURNAL OF IMMUNOLOGY

Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10

(2014) D. B. Engler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex

(2014) S. M. Man et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-1β induced by Helicobacter pylori infection enhances mouse gastric carcinogenesis

(2013) Yasuyuki Shigematsu et al.   CANCER LETTERS

The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL-1β production inHelicobacter pyloriinfected dendritic cells

(2013) Dong-Jae Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

Helicobacter pylori Cytotoxin-Associated Gene A Impairs Human Dendritic Cell Maturation and Function through IL-10-Mediated Activation of STAT3

(2013) R. Kaebisch et al.   JOURNAL OF IMMUNOLOGY

Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

(2013) Nina R. Salama et al.   NATURE REVIEWS MICROBIOLOGY

Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis

(2013) Yuko Akazawa et al.   PLoS One

Helicobacter pylori  -glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance

(2013) M. Oertli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of Bacteria by Inflammasomes

(2012) Jakob von Moltke et al.   Annual Review of Immunology

Helicobacter pyloriCagL dependent induction of gastrin expression via a novel αvβ5-integrin–integrin linked kinase signalling complex

(2012) Tobias Wiedemann et al.   GUT

An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages

(2012) Sonal Khare et al.   IMMUNITY

c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains

(2012) Doreen Mueller et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of the Pyrin Inflammasome by Intracellular Burkholderia cenocepacia

(2012) M. A. Gavrilin et al.   JOURNAL OF IMMUNOLOGY

Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis

(2012) Samuel L. Palframan et al.   Frontiers in Cellular and Infection Microbiology

Serine Phosphorylation of Cortactin Controls Focal Adhesion Kinase Activity and Cell Scattering Induced by Helicobacter pylori

(2011) Nicole Tegtmeyer et al.   Cell Host & Microbe

Helicobacter pylori VacA Induces Programmed Necrosis in Gastric Epithelial Cells

(2011) Jana N. Radin et al.   INFECTION AND IMMUNITY

Induction of TLR-2 and TLR-5 Expression by Helicobacter pylori Switches cagPAI-Dependent Signalling Leading to the Secretion of IL-8 and TNF-α

(2011) Suneesh Kumar Pachathundikandi et al.   PLoS One

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

(2010) L. E. Wroblewski et al.   CLINICAL MICROBIOLOGY REVIEWS

Morphologic, Genetic, and Biochemical Characterization of Helicobacter Magdeburgensis, a Novel Species Isolated from the Intestine of Laboratory Mice

(2010) Francisco Rivas Traverso et al.   HELICOBACTER

A Small Fibronectin-mimicking Protein from Bacteria Induces Cell Spreading and Focal Adhesion Formation

(2010) Nicole Tegtmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of disease: Helicobacter pylori virulence factors

(2010) Yoshio Yamaoka   Nature Reviews Gastroenterology & Hepatology

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

Enhanced M1 Macrophage Polarization in Human Helicobacter pylori-Associated Atrophic Gastritis and in Vaccinated Mice

(2010) Marianne Quiding-Järbrink et al.   PLoS One

What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori

(2010) Steffen Backert et al.   TRENDS IN MICROBIOLOGY

Coadaptation of Helicobacter pylori and humans: ancient history, modern implications

(2009) John C. Atherton et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain

(2009) N. B. Bryan et al.   JOURNAL OF IMMUNOLOGY

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

(2009) Robin R. Craven et al.   PLoS One

Overexpression of Interleukin-1β Induces Gastric Inflammation and Cancer and Mobilizes Myeloid-Derived Suppressor Cells in Mice

(2008) Shuiping Tu et al.   CANCER CELL

Integrin Subunit CD18 Is the T-Lymphocyte Receptor for the Helicobacter pylori Vacuolating Cytotoxin

(2008) Xaver Sewald et al.   Cell Host & Microbe

Host-Bacterial Interactions in Helicobacter pylori Infection

(2008) Manuel R. Amieva et al.   GASTROENTEROLOGY

Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse

(2008) N. Ohnishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE