Helicobacter pylori controls NLRP3 expression by regulating hsa-miR-223-3p and IL-10 in cultured and primary human immune cells

Helicobacter pylori induces IL-1β protein through the inflammasome activation in differentiated macrophagic cells

(2016) Shoichiro KAMEOKA et al.   BIOMEDICAL RESEARCH-TOKYO

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

(2016) Yuan He et al.   NATURE

NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β–mediated osteomyelitis

(2016) Prajwal Gurung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicobacter pylori-Mediated Protection from Allergy Is Associated with IL-10-Secreting Peripheral Blood Regulatory T Cells

(2016) Khiyam Hussain et al.   Frontiers in Immunology

Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1β expression and release

(2015) S.R. Hofmann et al.   CLINICAL IMMUNOLOGY

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5

(2015) Paul J. Baker et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Composition, structure and function of theHelicobacter pylori cagpathogenicity island encoded type IV secretion system

(2015) Steffen Backert et al.   Future Microbiology

Interleukin-1B signalling leads to increased survival of gastric carcinoma cells through a CREB-C/EBPβ-associated mechanism

(2015) Carlos Resende et al.   Gastric Cancer

The MUC1 mucin protects againstHelicobacter pyloripathogenesis in mice by regulation of the NLRP3 inflammasome

(2015) Garrett Z Ng et al.   GUT

Bacterial recognition pathways that lead to inflammasome activation

(2015) Kelly M. Storek et al.   IMMUNOLOGICAL REVIEWS

Helicobacter pylori–specific Protection Against Inflammatory Bowel Disease Requires the NLRP3 Inflammasome and IL-18

(2015) Daniela B. Engler et al.   INFLAMMATORY BOWEL DISEASES

Activation of NLRP3 inflammasome in human neutrophils by Helicobacter pylori infection

(2015) Erandi Pérez-Figueroa et al.   Innate Immunity

Helicobacter urease–induced activation of the TLR2/NLRP3/IL-18 axis protects against asthma

(2015) Katrin N. Koch et al.   JOURNAL OF CLINICAL INVESTIGATION

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation

(2015) Prajwal Gurung et al.   Scientific Reports

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

IL10Single Nucleotide Polymorphisms are Related to Upregulation of Constitutive IL-10 Production and Susceptibility toHelicobacter pyloriInfection

(2014) Shirleide Assis et al.   HELICOBACTER

Helicobacter pylori–Induced IL-1β Secretion in Innate Immune Cells Is Regulated by the NLRP3 Inflammasome and Requires the Cag Pathogenicity Island

(2014) Raphaela P. Semper et al.   JOURNAL OF IMMUNOLOGY

Helicobacter pylori CagL Y58/E59 Mutation Turns-Off Type IV Secretion-Dependent Delivery of CagA into Host Cells

(2014) Nicole Tegtmeyer et al.   PLoS One

Systematic Analysis of Phosphotyrosine Antibodies Recognizing Single Phosphorylated EPIYA-Motifs in CagA of Western-Type Helicobacter pylori Strains

(2014) Judith Lind et al.   PLoS One

Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction

(2014) Claire J Greenhill et al.   ARTHRITIS RESEARCH & THERAPY

The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL-1β production inHelicobacter pyloriinfected dendritic cells

(2013) Dong-Jae Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

(2013) Nina R. Salama et al.   NATURE REVIEWS MICROBIOLOGY

Electron Microscopic, Genetic and Protein Expression Analyses of Helicobacter acinonychis Strains from a Bengal Tiger

(2013) Nicole Tegtmeyer et al.   PLoS One

Recognition of Bacteria by Inflammasomes

(2012) Jakob von Moltke et al.   Annual Review of Immunology

Helicobacter pyloriCagL dependent induction of gastrin expression via a novel αvβ5-integrin–integrin linked kinase signalling complex

(2012) Tobias Wiedemann et al.   GUT

Distinct Roles of Secreted HtrA Proteases from Gram-negative Pathogens in Cleaving the Junctional Protein and Tumor Suppressor E-cadherin

(2012) Benjamin Hoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori–specific immune tolerance, and asthma protection

(2012) Mathias Oertli et al.   JOURNAL OF CLINICAL INVESTIGATION

c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains

(2012) Doreen Mueller et al.   JOURNAL OF CLINICAL INVESTIGATION

Live Helicobacter pylori in the root canal of endodontic-infected deciduous teeth

(2012) Christian Hirsch et al.   JOURNAL OF GASTROENTEROLOGY

Activation of the Pyrin Inflammasome by Intracellular Burkholderia cenocepacia

(2012) M. A. Gavrilin et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1  Production

(2012) M. Haneklaus et al.   JOURNAL OF IMMUNOLOGY

Peptidoglycan maturation enzymes affect flagellar functionality in bacteria

(2012) Sophie Roure et al.   MOLECULAR MICROBIOLOGY

Effects of Interleukin-10 Polymorphisms, Helicobacter pylori Infection, and Smoking on the Risk of Noncardia Gastric Cancer

(2012) Jeongseon Kim et al.   PLoS One

Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin

(2012) Manja Boehm et al.   Gut Pathogens

An RGD Helper Sequence in CagL of Helicobacter pylori Assists in Interactions with Integrins and Injection of CagA

(2012) Jens Conradi et al.   Frontiers in Cellular and Infection Microbiology

Serine Phosphorylation of Cortactin Controls Focal Adhesion Kinase Activity and Cell Scattering Induced by Helicobacter pylori

(2011) Nicole Tegtmeyer et al.   Cell Host & Microbe

MicroRNA evolution by arm switching

(2011) Sam Griffiths-Jones et al.   EMBO REPORTS

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

Induction of TLR-2 and TLR-5 Expression by Helicobacter pylori Switches cagPAI-Dependent Signalling Leading to the Secretion of IL-8 and TNF-α

(2011) Suneesh Kumar Pachathundikandi et al.   PLoS One

Helicobacter pylori CagL Activates ADAM17 to Induce Repression of the Gastric H, K-ATPase α Subunit

(2010) Arindam Saha et al.   GASTROENTEROLOGY

A Small Fibronectin-mimicking Protein from Bacteria Induces Cell Spreading and Focal Adhesion Formation

(2010) Nicole Tegtmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Coadaptation of Helicobacter pylori and humans: ancient history, modern implications

(2009) John C. Atherton et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Host-Bacterial Interactions in Helicobacter pylori Infection

(2008) Manuel R. Amieva et al.   GASTROENTEROLOGY