The Molecular Chaperone CCT/TRiC: An Essential Component of Proteostasis and a Potential Modulator of Protein Aggregation
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Molecular Chaperone CCT/TRiC: An Essential Component of Proteostasis and a Potential Modulator of Protein Aggregation
Authors
Keywords
-
Journal
Frontiers in Genetics
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-03-19
DOI
10.3389/fgene.2020.00172
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Local translation in neurons: visualization and function
- (2019) Christine E. Holt et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly
- (2019) Jorge Cuéllar et al. Nature Communications
- Interactions between monomeric CCTδ and p150 Glued : A novel function for CCTδ at the cell periphery distinct from the protein folding activity of the molecular chaperone CCT
- (2018) Meriem Echbarthi et al. EXPERIMENTAL CELL RESEARCH
- The substrate specificity of eukaryotic cytosolic chaperonin CCT
- (2018) Keith R. Willison PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- T-complex protein 1-ring complex enhances retrograde axonal transport by modulating tau phosphorylation
- (2018) Xu-Qiao Chen et al. TRAFFIC
- The role of the molecular chaperone CCT in protein folding and mediation of cytoskeleton-associated processes: implications for cancer cell biology
- (2018) Josefine Vallin et al. CELL STRESS & CHAPERONES
- The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction
- (2017) Begoña Sot et al. Scientific Reports
- Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls
- (2016) Srinivas Ayyadevara et al. AGING CELL
- TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease
- (2016) Xiaobei Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CCT complex restricts neuropathogenic protein aggregation via autophagy
- (2016) Mariana Pavel et al. Nature Communications
- The molecular chaperone CCT modulates the activity of the actin filament severing and capping protein gelsolin in vitro
- (2015) Andreas Svanström et al. CELL STRESS & CHAPERONES
- Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography
- (2015) Michele C. Darrow et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Over-Expression Analysis of All Eight Subunits of the Molecular Chaperone CCT in Mammalian Cells Reveals a Novel Function for CCTdelta
- (2015) Matthias Spiess et al. JOURNAL OF MOLECULAR BIOLOGY
- A novel function of the monomeric CCTε subunit connects the serum response factor pathway to chaperone-mediated actin folding
- (2015) Kerryn L. Elliott et al. MOLECULAR BIOLOGY OF THE CELL
- A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease
- (2014) Marc Brehme et al. Cell Reports
- Prefoldin Protects Neuronal Cells from Polyglutamine Toxicity by Preventing Aggregation Formation
- (2013) Erika Tashiro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Vaccinia-Related Kinase 2 Mediates Accumulation of Polyglutamine Aggregates via Negative Regulation of the Chaperonin TRiC
- (2013) S. Kim et al. MOLECULAR AND CELLULAR BIOLOGY
- Axonal transport deficits and neurodegenerative diseases
- (2013) Stéphanie Millecamps et al. NATURE REVIEWS NEUROSCIENCE
- Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes
- (2013) E. M. Sontag et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRiC’s tricks inhibit huntingtin aggregation
- (2013) Sarah H Shahmoradian et al. eLife
- Subunit order of eukaryotic TRiC/CCT chaperonin by cross-linking, mass spectrometry, and combinatorial homology modeling
- (2012) N. Kalisman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT
- (2012) Alexander Leitner et al. STRUCTURE
- Molecular chaperones in protein folding and proteostasis
- (2011) F. Ulrich Hartl et al. NATURE
- Interactions between the actin filament capping and severing protein gelsolin and the molecular chaperone CCT: evidence for nonclassical substrate interactions
- (2010) Karen I. Brackley et al. CELL STRESS & CHAPERONES
- Subunits of the chaperonin CCT interact with F-actin and influence cell shape and cytoskeletal assembly
- (2009) Karen I. Brackley et al. EXPERIMENTAL CELL RESEARCH
- The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation
- (2009) Stephen Tam et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started