On Facing the SARS-CoV-2 (COVID-19) with Combination of Nanomaterials and Medicine: Possible Strategies and First Challenges

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

(2020) Haibo Zhang et al.   INTENSIVE CARE MEDICINE

The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China

(2020) David S. Hui et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Coronavirus Infections—More Than Just the Common Cold

(2020) Catharine I. Paules et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents

(2020) G. Kampf et al.   JOURNAL OF HOSPITAL INFECTION

Analysis of angiotensin-converting enzyme 2 (ACE2) from different species sheds some light on cross-species receptor usage of a novel coronavirus 2019-nCoV

(2020) Rui Li et al.   JOURNAL OF INFECTION

A Unique Protein Self-Assembling Nanoparticle with Significant Advantages in Vaccine Development and Production

(2020) Daniel C. Carter et al.   Journal of Nanomaterials

Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury

(2020) Clark D Russell et al.   LANCET

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Anti-HCV, nucleotide inhibitors, repurposing against COVID-19

(2020) Abdo A. Elfiky   LIFE SCIENCES

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology

(2020) Eva Schrezenmeier et al.   Nature Reviews Rheumatology

Covid-19 — Navigating the Uncharted

(2020) Anthony S. Fauci et al.   NEW ENGLAND JOURNAL OF MEDICINE

First Case of 2019 Novel Coronavirus in the United States

(2020) Michelle L. Holshue et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

(2020) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Design and Characterization of Injectable Poly(Lactic-Co-Glycolic Acid) Pastes for Sustained and Local Drug Release

(2020) Veronika Schmitt et al.   PHARMACEUTICAL RESEARCH

The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals

(2020) Yuncheng Zhu et al.   Neuroscience Bulletin

Inductive Magnetic Nanoparticle Sensor Based on Microfluidic Chip Oil Detection Technology

(2020) Chenzhao Bai et al.   Micromachines

Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential

(2020) Jimin Xu et al.   ACS Infectious Diseases

Old Weapon for New Enemy: Drug Repurposing for Treatment of Newly Emerging Viral Diseases

(2020) Deyin Guo   VIROLOGICA SINICA

Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV-2

(2020) Yanxiao Han et al.   ACS Nano

COVID-19 infection and rheumatoid arthritis: Faraway, so close!

(2020) Ennio Giulio Favalli et al.   AUTOIMMUNITY REVIEWS

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus-related coronavirus model

(2020) Hua-Hao Fan et al.   CHINESE MEDICAL JOURNAL

New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

(2020) Christian A. Devaux et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Teicoplanin: an alternative drug for the treatment of COVID-19?

(2020) Sophie Alexandra Baron et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

(2020) Philippe Gautret et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression

(2020) Dan Zhou et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The convalescent sera option for containing COVID-19

(2020) Arturo Casadevall et al.   JOURNAL OF CLINICAL INVESTIGATION

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Rapid Identification of Potential Inhibitors of SARS‐CoV‐2 Main Protease by Deep Docking of 1.3 Billion Compounds

(2020) Anh-Tien Ton et al.   Molecular Informatics

Insights from nanomedicine into chloroquine efficacy against COVID-19

(2020) Tony Y. Hu et al.   Nature Nanotechnology

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies

(2020) Jianjun Gao et al.   BioScience Trends

Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review

(2020) Sasmita Poudel Adhikari et al.   Infectious Diseases of Poverty

Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?

(2020) Lei Fang et al.   Lancet Respiratory Medicine

Molecular immune pathogenesis and diagnosis of COVID-19

(2020) Xiaowei Li et al.   Journal of Pharmaceutical Analysis

Green synthesis and characterization of zinc oxide nanoparticles with antibacterial and antifungal activity

(2020) Akhilash Mohanan Pillai et al.   JOURNAL OF MOLECULAR STRUCTURE

Morinda morindoides: A systematic review of its therapeutic activities

(2020) A. Mohammed et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Silicon Quantum dots: Promising theranostic probes for the future

(2019) Vishnu Sankar Sivasankarapillai et al.   CURRENT DRUG TARGETS

Dissecting pharmacological effects of chloroquine in cancer treatment: interference with inflammatory signaling pathways

(2019) Lokman Varisli et al.   IMMUNOLOGY

Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8 + T cell responses

(2018) Youhui Si et al.   JOURNAL OF CONTROLLED RELEASE

Intranasal vaccination with M2e5x virus-like particles induces humoral and cellular immune responses conferring cross-protection against heterosubtypic influenza viruses

(2018) Young-Tae Lee et al.   PLoS One

Intranasal Nanovaccine Confers Homo- and Hetero-Subtypic Influenza Protection

(2018) Mi Qi et al.   Small

Nasal vaccination with r4M2e.HSP70c antigen encapsulated into N-trimethyl chitosan (TMC) nanoparticulate systems: Preparation and immunogenicity in a mouse model

(2018) Mehran Dabaghian et al.   VACCINE

Efficacy of mucosal polyanhydride nanovaccine against respiratory syncytial virus infection in the neonatal calf

(2018) Jodi L. McGill et al.   Scientific Reports

Mucosal Immunity and Protective Efficacy of Intranasal Inactivated Influenza Vaccine Is Improved by Chitosan Nanoparticle Delivery in Pigs

(2018) Santosh Dhakal et al.   Frontiers in Immunology

Biodegradable nanoparticle delivery of inactivated swine influenza virus vaccine provides heterologous cell-mediated immune response in pigs

(2017) Santosh Dhakal et al.   JOURNAL OF CONTROLLED RELEASE

RSV N-nanorings fused to palivizumab-targeted neutralizing epitope as a nanoparticle RSV vaccine

(2017) Pierre-Louis Hervé et al.   Nanomedicine-Nanotechnology Biology and Medicine

Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus

(2017) Ben Hu et al.   PLoS Pathogens

Silver Nanoparticle Based Codelivery of Oseltamivir to Inhibit the Activity of the H1N1 Influenza Virus through ROS-Mediated Signaling Pathways

(2016) Yinghua Li et al.   ACS Applied Materials & Interfaces

Virus-like particle vaccine by intranasal vaccination elicits protective immunity against respiratory syncytial viral infection in mice

(2016) Mengying Cai et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant

(2016) Joseph R. Francica et al.   BIOCONJUGATE CHEMISTRY

Pulmonary Involvement in Patients With Hemophagocytic Lymphohistiocytosis

(2016) Amélie Seguin et al.   CHEST

Nanoparticle-Mediated Nonviral DNA Delivery for Effective Inhibition of Influenza a Viruses in Cells

(2016) Asya S. Levina et al.   IEEE TRANSACTIONS ON NANOTECHNOLOGY

SARS and MERS: recent insights into emerging coronaviruses

(2016) Emmie de Wit et al.   NATURE REVIEWS MICROBIOLOGY

Comparing the immune response to a novel intranasal nanoparticle PLGA vaccine and a commercial BPI3V vaccine in dairy calves

(2015) Fawad Mansoor et al.   BMC Veterinary Research

Emerging drugs for acute lung injury

(2015) Daniela Impellizzeri et al.   EXPERT OPINION ON EMERGING DRUGS

Conjugating influenza a (H1N1) antigen to n-trimethylaminoethylmethacrylate chitosan nanoparticles improves the immunogenicity of the antigen after nasal administration

(2015) Qingfeng Liu et al.   JOURNAL OF MEDICAL VIROLOGY

Integration of reverse transcriptase loop-mediated isothermal amplification with an immunochromatographic strip on a centrifugal microdevice for influenza A virus identification

(2015) J. H. Jung et al.   LAB ON A CHIP

In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

(2015) Geoffrey M Lynn et al.   NATURE BIOTECHNOLOGY

MPG-based nanoparticle: An efficient delivery system for enhancing the potency of DNA vaccine expressing HPV16E7

(2015) Tayebeh Saleh et al.   VACCINE

Overcoming Drug Development Bottlenecks With Repurposing: Old drugs learn new tricks

(2014) Stephen M Strittmatter   NATURE MEDICINE

Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections

(2014) Zhen Zou et al.   Nature Communications

The use of Nanotrap particles for biodefense and emerging infectious disease diagnostics

(2014) Nazly Shafagati et al.   Pathogens and Disease

Chitosan Nanoparticle Encapsulated Hemagglutinin-Split Influenza Virus Mucosal Vaccine

(2013) Chompoonuch Sawaengsak et al.   AAPS PHARMSCITECH

Sialylneolacto-N-tetraose c (LSTc)-bearing Liposomal Decoys Capture Influenza A Virus

(2013) Gabriel L. Hendricks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Subnucleocapsid Nanoplatform for Mucosal Vaccination against Influenza Virus That Targets the Ectodomain of Matrix Protein 2

(2013) P.-L. Herve et al.   JOURNAL OF VIROLOGY

Adult haemophagocytic syndrome

(2013) Manuel Ramos-Casals et al.   LANCET

Treatment of Acute Lung Injury: Current and Emerging Pharmacological Therapies

(2013) Rob Sweeney et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

New treatments for influenza

(2012) Sailen Barik   BMC Medicine

Pulmotoxicological effects caused by long-term titanium dioxide nanoparticles exposure in mice

(2012) Qingqing Sun et al.   JOURNAL OF HAZARDOUS MATERIALS

Persistent DNA Damage Measured by Comet Assay of Sprague Dawley Rat Lung Cells after Five Days of Inhalation Exposure and 1 Month Post-Exposure to Dispersed Multi-Wall Carbon Nanotubes (MWCNTs) Generated by New MWCNT Aerosol Generation System

(2012) Jin Sik Kim et al.   TOXICOLOGICAL SCIENCES

Current progress of siRNA/shRNA therapeutics in clinical trials

(2011) John C. Burnett et al.   Biotechnology Journal

Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung

(2011) Matthew C. Duch et al.   NANO LETTERS

Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ionsin vitroandin vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs

(2011) Wan-Seob Cho et al.   Nanotoxicology

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanotoxicology—A Pathologist’s Perspective

(2011) Ann F. Hubbs et al.   TOXICOLOGIC PATHOLOGY

Different host cell proteases activate the SARS-coronavirus spike-protein for cell–cell and virus–cell fusion

(2011) Graham Simmons et al.   VIROLOGY

RNA Interference Therapy in Lung Transplant Patients Infected with Respiratory Syncytial Virus

(2010) Martin R. Zamora et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of Air Temperature and Relative Humidity on Coronavirus Survival on Surfaces

(2010) L. M. Casanova et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Consensus Statement on the Adherence to Clinical and Laboratory Standards Institute (CLSI) Antimicrobial Susceptibility Testing Guidelines (CLSI-2010 and CLSI-2010-update) for Enterobacteriaceae in Clinical Microbiology Laboratories in Taiwan

(2010) Po-Ren Hsueh et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Multistrain influenza protection induced by a nanoparticulate mucosal immunotherapeutic

(2010) W Tai et al.   Mucosal Immunology

Ultrafine particles from diesel vehicle emissions at different driving cycles induce differential vascular pro-inflammatory responses: Implication of chemical components and NF-κB signaling

(2010) Rongsong Li et al.   Particle and Fibre Toxicology

Coronaviruses post-SARS: update on replication and pathogenesis

(2009) Stanley Perlman et al.   NATURE REVIEWS MICROBIOLOGY

Global Transmission of Oseltamivir-Resistant Influenza

(2009) Anne Moscona   NEW ENGLAND JOURNAL OF MEDICINE

Nanoparticles up-regulate tumor necrosis factor-α and CXCL8 via reactive oxygen species and mitogen-activated protein kinase activation

(2009) Hye-Mi Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Poly(γ-glutamic acid) nano-particles combined with mucosal influenza virus hemagglutinin vaccine protects against influenza virus infection in mice

(2009) Shigefumi Okamoto et al.   VACCINE

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis

(2008) A. A. Shvedova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Characterization of the Prefusion and Transition States of Severe Acute Respiratory Syndrome Coronavirus S2-HR2†

(2008) Susanna McReynolds et al.   BIOCHEMISTRY

Peptide Nanoparticles as Novel Immunogens: Design and Analysis of a Prototypic Severe Acute Respiratory Syndrome Vaccine

(2008) Tais A. P. F. Pimentel et al.   Chemical Biology & Drug Design

Polymer Chemistry Influences Monocytic Uptake of Polyanhydride Nanospheres

(2008) Bret D. Ulery et al.   PHARMACEUTICAL RESEARCH

Sub-Nucleocapsid Nanoparticles: A Nasal Vaccine against Respiratory Syncytial Virus

(2008) Xavier Roux et al.   PLoS One

Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution

(2008) Qinghong Zeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells

(2008) Eun-Jung Park et al.   TOXICOLOGY LETTERS