The Microbiome in Cystic Fibrosis Pulmonary Disease

Respiratory mycobiome and suggestion of inter-kingdom network during acute pulmonary exacerbation in cystic fibrosis

(2020) Perrine Soret et al.   Scientific Reports

Interactions between the gut microbiome and host gene regulation in cystic fibrosis

(2020) Gargi Dayama et al.   Genome Medicine

The impact of Lactococcus lactis (probiotic nasal rinse) co‐culture on growth of patient‐derived strains of Pseudomonas aeruginosa

(2020) Do‐Yeon Cho et al.   International Forum of Allergy & Rhinology

CFTR dysregulation drives active selection of the gut microbiome

(2020) Stacey M. Meeker et al.   PLoS Pathogens

The Cross-Talk Between Gut Microbiota and Lungs in Common Lung Diseases

(2020) Dapeng Zhang et al.   Frontiers in Microbiology

Variant classifications, databases and genotype-phenotype correlations

(2020) C. Raynal et al.   ARCHIVES DE PEDIATRIE

Lung function and microbiota diversity in cystic fibrosis

(2020) Leah Cuthbertson et al.   Microbiome

Anaerobes in cystic fibrosis patients’ airways

(2019) Claudie Lamoureux et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Clinical and microbiological characteristics of cystic fibrosis adults never colonized by Pseudomonas aeruginosa: Analysis of the French CF registry

(2019) Réchana Vongthilath et al.   PLoS One

Performance of Microbiome Sequence Inference Methods in Environments with Varying Biomass

(2019) Vincent Caruso et al.   mSystems

Emerging Therapeutic Approaches for Cystic Fibrosis. From Gene Editing to Personalized Medicine

(2019) Iwona Pranke et al.   Frontiers in Pharmacology

The effects of cycled inhaled aztreonam on the cystic fibrosis (CF) lung microbiome

(2019) Alya A. Heirali et al.   Journal of Cystic Fibrosis

The Yin and Yang of Streptococcus Lung Infections in Cystic Fibrosis: A Model for Studying Polymicrobial Interactions

(2019) Jessie E. Scott et al.   JOURNAL OF BACTERIOLOGY

Correlating CFTR Function with Clinical Features to Inform Precision Treatment of Cystic Fibrosis

(2019) Allison F McCague et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis

(2019) Charles R. Esther et al.   Science Translational Medicine

Cystic Fibrosis Rapid Response: Translating Multi-omics Data into Clinically Relevant Information

(2019) Ana Georgina Cobián Güemes et al.   mBio

Direct Lung Sampling Indicates That Established Pathogens Dominate Early Infections in Children with Cystic Fibrosis

(2019) Peter Jorth et al.   Cell Reports

Transcriptome analysis of the distal small intestine of Cftr null mice

(2019) Pauline T. Ikpa et al.   GENOMICS

Altered Stool Microbiota of Infants with Cystic Fibrosis Shows a Reduction in Genera Associated with Immune Programming from Birth

(2019) Katherine M. Antosca et al.   JOURNAL OF BACTERIOLOGY

Ketogenic Diet and Microbiota: Friends or Enemies?

(2019) Antonio Paoli et al.   Genes

The impact of CFTR modulator therapies on CF airway microbiology

(2019) Geraint B. Rogers et al.   Journal of Cystic Fibrosis

The future of cystic fibrosis care: a global perspective

(2019) Scott C Bell et al.   Lancet Respiratory Medicine

A Metabolome- and Metagenome-Wide Association Network Reveals Microbial Natural Products and Microbial Biotransformation Products from the Human Microbiota

(2019) Liu Cao et al.   mSystems

Preliminary safety assessment of a new Bacteroides fragilis isolate

(2019) Huizi Tan et al.   FOOD AND CHEMICAL TOXICOLOGY

In vitro evolution of Pseudomonas aeruginosa AA2 biofilms in the presence of cystic fibrosis lung microbiome members

(2019) Eva Vandeplassche et al.   Scientific Reports

Despite Antagonism in vitro, Pseudomonas aeruginosa Enhances Staphylococcus aureus Colonization in a Murine Lung Infection Model

(2019) Guillaume Millette et al.   Frontiers in Microbiology

Exploring the Archaeome: Detection of Archaeal Signatures in the Human Body

(2019) Manuela R. Pausan et al.   Frontiers in Microbiology

The Lung Microbiota of Healthy Mice are Highly Variable, Cluster by Environment, and Reflect Variation in Baseline Lung Innate Immunity

(2018) Robert P. Dickson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cystic Fibrosis Disease Modifiers: Complex Genetics Defines the Phenotypic Diversity in a Monogenic Disease

(2018) Wanda K. O'Neal et al.   Annual Review of Genomics and Human Genetics

Anaerobic bacteria cultured from cystic fibrosis airways correlate to milder disease: a multisite study

(2018) Marianne S. Muhlebach et al.   EUROPEAN RESPIRATORY JOURNAL

Antibiotic exposure and interpersonal variance mask the effect of ivacaftor on respiratory microbiota composition

(2018) Anton Y. Peleg et al.   Journal of Cystic Fibrosis

Role of vitamin D on gut microbiota in cystic fibrosis

(2018) Mansi Kanhere et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Long-term dietary (n-3) polyunsaturated fatty acids show benefits to the lungs of Cftr F508del mice

(2018) Céline Portal et al.   PLoS One

Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children

(2018) Marianne S. Muhlebach et al.   PLoS Pathogens

Sinus Microanatomy and Microbiota in a Rabbit Model of Rhinosinusitis

(2018) Do-Yeon Cho et al.   Frontiers in Cellular and Infection Microbiology

The CF-Sputum Induction Trial (CF-SpIT) to assess lower airway bacterial sampling in young children with cystic fibrosis: a prospective internally controlled interventional trial

(2018) Katherine Ronchetti et al.   Lancet Respiratory Medicine

Animal models for cystic fibrosis liver disease (CFLD)

(2018) Romina Fiorotto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lower airway microbiota for ‘biomarker’ measurements of cystic fibrosis disease progression?

(2018) Laura J Sherrard et al.   THORAX

Sputum microbiota is predictive of long-term clinical outcomes in young adults with cystic fibrosis

(2018) Nicole Acosta et al.   THORAX

Diet, Microbiota and Gut-Lung Connection

(2018) Swadha Anand et al.   Frontiers in Microbiology

Differences in the lower airway microbiota of infants with and without cystic fibrosis

(2018) Katherine B. Frayman et al.   Journal of Cystic Fibrosis

The lung and gut microbiome: what has to be taken into consideration for cystic fibrosis?

(2018) Geneviève Héry-Arnaud et al.   Journal of Cystic Fibrosis

Lower Airway Virology in Health and Disease—From Invaders to Symbionts

(2018) Lina Jankauskaitė et al.   Medicina-Lithuania

Impact of CFTR modulation with Ivacaftor on Gut Microbiota and Intestinal Inflammation

(2018) Chee Y. Ooi et al.   Scientific Reports

Prediction of the intestinal resistome by a three-dimensional structure-based method

(2018) Etienne Ruppé et al.   Nature Microbiology

Concordance between upper and lower airway microbiota in infants with cystic fibrosis

(2017) Sabine M.P.J. Prevaes et al.   EUROPEAN RESPIRATORY JOURNAL

Airway microbiota across age and disease spectrum in cystic fibrosis

(2017) Edith T. Zemanick et al.   EUROPEAN RESPIRATORY JOURNAL

A Different Microbiome Gene Repertoire in the Airways of Cystic Fibrosis Patients with Severe Lung Disease

(2017) Giovanni Bacci et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Airway microbial metagenomics

(2017) Katarzyna Pienkowska et al.   MICROBES AND INFECTION

The lower airway microbiota in early cystic fibrosis lung disease: a longitudinal analysis

(2017) Katherine B Frayman et al.   THORAX

First Insights into the Diverse Human Archaeome: Specific Detection of Archaea in the Gastrointestinal Tract, Lung, and Nose and on Skin

(2017) Kaisa Koskinen et al.   mBio

A Metagenomic and in Silico Functional Prediction of Gut Microbiota Profiles May Concur in Discovering New Cystic Fibrosis Patient-Targeted Probiotics

(2017) Pamela Vernocchi et al.   Nutrients

The WinCF Model - An Inexpensive and Tractable Microcosm of a Mucus Plugged Bronchiole to Study the Microbiology of Lung Infections

(2017) William J. Comstock et al.   Jove-Journal of Visualized Experiments

Optimizing methods and dodging pitfalls in microbiome research

(2017) Dorothy Kim et al.   Microbiome

The Microbiome and the Respiratory Tract

(2016) Robert P. Dickson et al.   Annual Review of Physiology

Development of the respiratory tract microbiota in cystic fibrosis

(2016) Emma M. de Koff et al.   CURRENT OPINION IN PULMONARY MEDICINE

Cystic Fibrosis

(2016) Marie-Luise Brennan et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Cystic fibrosis

(2016) J Stuart Elborn   LANCET

Molecular Genetics of Cystic Fibrosis Transmembrane Conductance Regulator

(2016) Patrick R. Sosnay et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Analysis of Lung Microbiota in Bronchoalveolar Lavage, Protected Brush and Sputum Samples from Subjects with Mild-To-Moderate Cystic Fibrosis Lung Disease

(2016) Deborah A. Hogan et al.   PLoS One

Translating the genetics of cystic fibrosis to personalized medicine

(2016) Harriet Corvol et al.   Translational Research

Streptomycin treatment alters the intestinal microbiome, pulmonary T cell profile and airway hyperresponsiveness in a cystic fibrosis mouse model

(2016) Mark Bazett et al.   Scientific Reports

Disrupted progression of the intestinal microbiota with age in children with cystic fibrosis

(2016) Shaun Nielsen et al.   Scientific Reports

The nasal microbiota in infants with cystic fibrosis in the first year of life: a prospective cohort study

(2016) Moana Mika et al.   Lancet Respiratory Medicine

Metabolomics of pulmonary exacerbations reveals the personalized nature of cystic fibrosis disease

(2016) Robert A. Quinn et al.   PeerJ

Data Mining of Lung Microbiota in Cystic Fibrosis Patients

(2016) Jianguo Li et al.   PLoS One

Respiratory microbiota resistance and resilience to pulmonary exacerbation and subsequent antimicrobial intervention

(2015) Leah Cuthbertson et al.   ISME Journal

Cohort Study of Airway Mycobiome in Adult Cystic Fibrosis Patients: Differences in Community Structure between Fungi and Bacteria Reveal Predominance of Transient Fungal Elements

(2015) Rolf Kramer et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Associations between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis

(2015) Anne G. Hoen et al.   JOURNAL OF PEDIATRICS

Cystic fibrosis mouse model-dependent intestinal structure and gut microbiome

(2015) Mark Bazett et al.   MAMMALIAN GENOME

Origins of Cystic Fibrosis Lung Disease

(2015) David A. Stoltz et al.   NEW ENGLAND JOURNAL OF MEDICINE

The vocabulary of microbiome research: a proposal

(2015) Julian R. Marchesi et al.   Microbiome

Insights into the respiratory tract microbiota of patients with cystic fibrosis during early Pseudomonas aeruginosa colonization

(2015) Marlène Keravec et al.   SpringerPlus

Comparison of Microbiomes from Different Niches of Upper and Lower Airways in Children and Adolescents with Cystic Fibrosis

(2015) Sébastien Boutin et al.   PLoS One

Impact of the CFTR-Potentiator Ivacaftor on Airway Microbiota in Cystic Fibrosis Patients Carrying A G551D Mutation

(2015) Cédric Bernarde et al.   PLoS One

Clinical Mechanism of the Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor in G551D-mediated Cystic Fibrosis

(2014) Steven M. Rowe et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Specialized Metabolites from the Microbiome in Health and Disease

(2014) Gil Sharon et al.   Cell Metabolism

Correction: Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Allelic Variants Relate to Shifts in Faecal Microbiota of Cystic Fibrosis Patients

(2014) Serena Schippa et al.   PLoS One

Characterization and quantification of the fungal microbiome in serial samples from individuals with cystic fibrosis

(2014) Sven D Willger et al.   Microbiome

Lung Phenotype of Juvenile and Adult Cystic Fibrosis Transmembrane Conductance Regulator–Knockout Ferrets

(2013) Xingshen Sun et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Probiotics: A new way to fight bacterial pulmonary infections?

(2013) Y. Alexandre et al.   MEDECINE ET MALADIES INFECTIEUSES

Inflammation and Airway Microbiota during Cystic Fibrosis Pulmonary Exacerbations

(2013) Edith T. Zemanick et al.   PLoS One

Microbiota and Metabolite Profiling Reveal Specific Alterations in Bacterial Community Structure and Environment in the Cystic Fibrosis Airway during Exacerbation

(2013) Kate B. Twomey et al.   PLoS One

Microbial culturomics: paradigm shift in the human gut microbiome study

(2012) J.-C. Lagier et al.   CLINICAL MICROBIOLOGY AND INFECTION

Dysbiosis of bifidobacteria and Clostridium cluster XIVa in the cystic fibrosis fecal microbiota

(2012) Gwen Duytschaever et al.   Journal of Cystic Fibrosis

The Airway Microbiota in Cystic Fibrosis: A Complex Fungal and Bacterial Community—Implications for Therapeutic Management

(2012) Laurence Delhaes et al.   PLoS One

Decade-long bacterial community dynamics in cystic fibrosis airways

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of Artificial Sputum Medium to Test Antibiotic Efficacy Against Pseudomonas aeruginosa in Conditions More Relevant to the Cystic Fibrosis Lung

(2012) Sebastian Kirchner et al.   Jove-Journal of Visualized Experiments

Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract

(2011) Emily S. Charlson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Bacteriophages as vehicles of the resistome in cystic fibrosis

(2011) J. M. Rolain et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Culture Enriched Molecular Profiling of the Cystic Fibrosis Airway Microbiome

(2011) Christopher D. Sibley et al.   PLoS One

Relationship between cystic fibrosis respiratory tract bacterial communities and age, genotype, antibiotics and Pseudomonas aeruginosa

(2010) Vanja Klepac-Ceraj et al.   ENVIRONMENTAL MICROBIOLOGY

Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities

(2010) Christopher J van der Gast et al.   ISME Journal

Airway Microbiota and Pathogen Abundance in Age-Stratified Cystic Fibrosis Patients

(2010) Michael J. Cox et al.   PLoS One

Non-Invasive Tests in Animal Models and Humans: A New Paradigm for Assessing Efficacy of Biologics Including Prebiotics and Probiotics

(2008) R. Butler   CURRENT PHARMACEUTICAL DESIGN

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA