Metabolomics of pulmonary exacerbations reveals the personalized nature of cystic fibrosis disease

A statistical model to predict one-year risk of death in patients with cystic fibrosis

(2015) Shawn D. Aaron et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Illuminating the dark matter in metabolomics: Fig. 1.

(2015) Ricardo R. da Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The daily dynamics of cystic fibrosis airway microbiota during clinical stability and at exacerbation

(2015) Lisa A Carmody et al.   Microbiome

A Winogradsky-based culture system shows an association between microbial fermentation and cystic fibrosis exacerbation

(2014) Robert A Quinn et al.   ISME Journal

Breath gas metabolites and bacterial metagenomes from cystic fibrosis airways indicate active pH neutral 2,3-butanedione fermentation

(2014) Katrine L Whiteson et al.   ISME Journal

Putting lung function and physiology into perspective: cystic fibrosis in adults

(2014) Alex Horsley et al.   RESPIROLOGY

Cystic Fibrosis Therapy: A Community Ecology Perspective

(2013) Douglas Conrad et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Ceramide mediates lung fibrosis in cystic fibrosis

(2013) Regan Ziobro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Discovery of metabolite biomarkers: flux analysis and reaction-reaction network approach

(2013) Limin Li et al.   BMC Systems Biology

Clinical Insights from Metagenomic Analysis of Sputum Samples from Patients with Cystic Fibrosis

(2013) Y. W. Lim et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Microbiota and Metabolite Profiling Reveal Specific Alterations in Bacterial Community Structure and Environment in the Cystic Fibrosis Airway during Exacerbation

(2013) Kate B. Twomey et al.   PLoS One

Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation

(2013) Alex R Horsley et al.   THORAX

Metagenomics and metatranscriptomics: Windows on CF-associated viral and microbial communities

(2012) Yan Wei Lim et al.   Journal of Cystic Fibrosis

The Adult Cystic Fibrosis Airway Microbiota Is Stable over Time and Infection Type, and Highly Resilient to Antibiotic Treatment of Exacerbations

(2012) Anthony A. Fodor et al.   PLoS One

Telomere length in early life predicts lifespan

(2012) B. J. Heidinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pulmonary exacerbations in cystic fibrosis

(2011) Antine E. Stenbit et al.   CURRENT OPINION IN PULMONARY MEDICINE

Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset

(2011) Geraint B Rogers et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Pulmonary exacerbation: Towards a definition for use in clinical trials. Report from the EuroCareCF Working Group on outcome parameters in clinical trials

(2011) D. Bilton et al.   Journal of Cystic Fibrosis

Does bacterial density in cystic fibrosis sputum increase prior to pulmonary exacerbation?

(2011) Franziska A. Stressmann et al.   Journal of Cystic Fibrosis

Exacerbation frequency and clinical outcomes in adult patients with cystic fibrosis

(2011) K. de Boer et al.   THORAX

Lipids in cystic fibrosis

(2011) Katrin Anne Becker et al.   Expert Review of Respiratory Medicine

Ceramide Is Increased in the Lower Airway Epithelium of People with Advanced Cystic Fibrosis Lung Disease

(2010) Malcolm Brodlie et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Failure to Recover to Baseline Pulmonary Function after Cystic Fibrosis Pulmonary Exacerbation

(2010) Don B. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses

(2010) Christian C. Yost et al.   BIOCHIMIE

UMD-CFTR: A database dedicated to CF and CFTR-related disorders

(2010) Corinne Bareil et al.   HUMAN MUTATION

Critical Modifier Role of Membrane-Cystic Fibrosis Transmembrane Conductance Regulator-Dependent Ceramide Signaling in Lung Injury and Emphysema

(2010) M. Bodas et al.   JOURNAL OF IMMUNOLOGY

Quantification of the Relative Contribution of Environmental and Genetic Factors to Variation in Cystic Fibrosis Lung Function

(2010) J. Michael Collaco et al.   JOURNAL OF PEDIATRICS

Pulmonary exacerbations are associated with subsequent FEV1 decline in both adults and children with cystic fibrosis

(2010) Don B. Sanders et al.   PEDIATRIC PULMONOLOGY

From differentiating metabolites to biomarkers

(2009) Albert Koulman et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Sphingolipids in inflammation: pathological implications and potential therapeutic targets

(2009) Graeme F. Nixon   BRITISH JOURNAL OF PHARMACOLOGY

Antibacterial-Resistant Pseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

(2009) P. D. Lister et al.   CLINICAL MICROBIOLOGY REVIEWS

“Omics” data and levels of evidence for biomarker discovery

(2008) Debashis Ghosh et al.   GENOMICS

Platelet Activating Factor as a Mediator and Therapeutic Approach in Bronchial Asthma

(2008) A. Kasperska-Zajac et al.   INFLAMMATION

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

(2008) Volker Teichgräber et al.   NATURE MEDICINE