Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability
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Title
Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability
Authors
Keywords
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Journal
Genes
Volume 11, Issue 5, Pages 556
Publisher
MDPI AG
Online
2020-05-18
DOI
10.3390/genes11050556
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- A Phase I Pharmacokinetic and Pharmacodynamic Study of CHR-3996, an Oral Class I Selective Histone Deacetylase Inhibitor in Refractory Solid Tumors
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- Chromatin associated Sin3A is essential for male germ cell lineage in the mouse
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- HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment
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- An Essential Role for Histone Deacetylase 4 in Synaptic Plasticity and Memory Formation
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- HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle
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- Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia
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- Molecular mechanisms and potential functions of histone demethylases
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- Sin3a acts through a multi-gene module to regulate invasion in Drosophila and human tumors
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- HDAC1 and HDAC2 are Differentially Expressed in Endometriosis
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- Unknown
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- Sensitization to γ-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells
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- Acetylation/Deacetylation Modulates the Stability of DNA Replication Licensing Factor Cdt1
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- The many roles of histone deacetylases in development and physiology: implications for disease and therapy
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- The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men
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