Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways
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Title
Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 9, Issue 8, Pages -
Publisher
Springer Nature
Online
2018-07-26
DOI
10.1038/s41419-018-0788-2
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Note: Only part of the references are listed.- Recent advances in the discovery of potent and selective HDAC6 inhibitors
- (2018) Xiu-Xiu Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathways
- (2018) Manon Lernoux et al. PHARMACOLOGICAL RESEARCH
- Synthesis and applications of benzohydroxamic acid-based histone deacetylase inhibitors
- (2017) Rob De Vreese et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Downregulation of microRNA-30d promotes cell proliferation and invasion by targeting LRH-1 in colorectal carcinoma
- (2017) Likun Yan et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Oesophageal cancer
- (2017) Jesper Lagergren et al. LANCET
- HDAC6 regulates microRNA-27b that suppresses proliferation, promotes apoptosis and target MET in diffuse large B-cell lymphoma
- (2017) Y J Jia et al. LEUKEMIA
- Clinical, cellular, and bioinformatic analyses reveal involvement of WRAP53 overexpression in carcinogenesis of lung adenocarcinoma
- (2017) Xiao-Shuai Yuan et al. TUMOR BIOLOGY
- Regulation of Insulin Resistance by Multiple MiRNAs via Targeting the GLUT4 Signalling Pathway
- (2016) Tong Zhou et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Ricolinostat plus lenalidomide, and dexamethasone in relapsed or refractory multiple myeloma: a multicentre phase 1b trial
- (2016) Andrew J Yee et al. LANCET ONCOLOGY
- ACY-1215 accelerates vemurafenib induced cell death of BRAF-mutant melanoma cells via induction of ER stress and inhibition of ERK activation
- (2016) Ueihuei Peng et al. ONCOLOGY REPORTS
- Downregulation of RUVBL1 inhibits proliferation of lung adenocarcinoma cells by G1/S phase cell cycle arrest via multiple mechanisms
- (2016) Xiao-Shuai Yuan et al. TUMOR BIOLOGY
- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- MicroRNA-30d-5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non-small cell lung cancer
- (2015) Di Chen et al. CANCER LETTERS
- Dual Targeting of Protein Degradation Pathways with the Selective HDAC6 Inhibitor ACY-1215 and Bortezomib Is Synergistic in Lymphoma
- (2015) J. E. Amengual et al. CLINICAL CANCER RESEARCH
- MicroRNA-221 governs tumor suppressor HDAC6 to potentiate malignant progression of liver cancer
- (2015) Hyun Jin Bae et al. JOURNAL OF HEPATOLOGY
- miR-433 inhibits oral squamous cell carcinoma (OSCC) cell growth and metastasis by targeting HDAC6
- (2015) Xiao-chun Wang et al. ORAL ONCOLOGY
- Histone deacetylase 6 promotes growth of glioblastoma through inhibition of SMAD2 signaling
- (2015) Shun Li et al. TUMOR BIOLOGY
- Histone deacetylase 6 in health and disease
- (2015) Carole Seidel et al. Epigenomics
- Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma
- (2015) Nina A. Sibbesen et al. Oncotarget
- In Vitro and In Vivo Interactions between the HDAC6 Inhibitor Ricolinostat (ACY1215) and the Irreversible Proteasome Inhibitor Carfilzomib in Non-Hodgkin Lymphoma Cells
- (2014) G. Dasmahapatra et al. MOLECULAR CANCER THERAPEUTICS
- Proteomic identification and functional characterization of MYH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity
- (2014) Linlin Zhang et al. Protein & Cell
- MiR-30d induces apoptosis and is regulated by the Akt/FOXO pathway in renal cell carcinoma
- (2013) Chenglin Wu et al. CELLULAR SIGNALLING
- A microenvironment-mediated c-Myc/miR-548m/HDAC6 amplification loop in non-Hodgkin B cell lymphomas
- (2013) Tint Lwin et al. JOURNAL OF CLINICAL INVESTIGATION
- Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma
- (2012) L. Santo et al. BLOOD
- HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance
- (2012) Michaël Van Damme et al. Epigenetics
- Down-Regulation of the miR-25 and miR-30d Contributes to the Development of Anaplastic Thyroid Carcinoma Targeting the Polycomb Protein EZH2
- (2012) Francesco Esposito et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Overexpression of histone deacetylase 6 contributes to accelerated migration and invasion activity of hepatocellular carcinoma cells
- (2012) KIMINORI KANNO et al. ONCOLOGY REPORTS
- Targeting the phosphoinositide 3-kinase pathway in cancer
- (2009) Pixu Liu et al. NATURE REVIEWS DRUG DISCOVERY
- Amplification and Overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in Medulloblastoma
- (2009) Yuan Lu et al. PLoS One
- Ubiquitin Proteasome System Stress Underlies Synergistic Killing of Ovarian Cancer Cells by Bortezomib and a Novel HDAC6 Inhibitor
- (2008) M. Bazzaro et al. CLINICAL CANCER RESEARCH
- Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma
- (2008) L Marquard et al. HISTOPATHOLOGY
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