Mitochondrial Quality Control and Cellular Proteostasis: Two Sides of the Same Coin

Reductive Stress Causes Pathological Cardiac Remodeling and Diastolic Dysfunction

(2020) Gobinath Shanmugam et al.   ANTIOXIDANTS & REDOX SIGNALING

Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination

(2020) Na Xu et al.   CIRCULATION RESEARCH

Mitochondrial LonP1 protects cardiomyocytes from ischemia/reperfusion injury in vivo

(2019) Sundararajan Venkatesh et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Aggregation of Respiratory Complex Subunits Marks the Onset of Proteotoxicity in Proteasome Inhibited Cells

(2019) Shivali Rawat et al.   JOURNAL OF MOLECULAR BIOLOGY

Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis

(2019) Erik A. Blackwood et al.   Nature Communications

Exogenous Ketone Supplementation Decreased the Lipopolysaccharide-Induced Increase in Absence Epileptic Activity in Wistar Albino Glaxo Rijswijk Rats

(2019) Zsolt Kovács et al.   Frontiers in Molecular Neuroscience

Transcription Factor EB Activation Rescues Advanced αB‐Crystallin Mutation‐Induced Cardiomyopathy by Normalizing Desmin Localization

(2019) Xiucui Ma et al.   Journal of the American Heart Association

Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy

(2019) Mingming Tong et al.   CIRCULATION RESEARCH

Cardioprotective Effect of the Mitochondrial Unfolded Protein Response During Chronic Pressure Overload

(2019) Ioannis Smyrnias et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and Affects Markers of the Circadian Clock, Aging, and Autophagy in Humans

(2019) Humaira Jamshed et al.   Nutrients

Mitofusin 2 Participates in Mitophagy and Mitochondrial Fusion Against Angiotensin II-Induced Cardiomyocyte Injury

(2019) Wenjun Xiong et al.   Frontiers in Physiology

Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides

(2019) Phung N. Thai et al.   Frontiers in Physiology

Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure

(2019) Feifei Fan et al.   CELL DEATH AND DIFFERENTIATION

Protein Misfolding in Cardiac Disease

(2019) Christoph Hofmann et al.   CIRCULATION

Cardioprotection by the mitochondrial unfolded protein response requires ATF5

(2019) Yves T. Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans

(2019) Slaven Stekovic et al.   Cell Metabolism

Endoplasmic Reticulum Stress Activates Unfolded Protein Response Signaling and Mediates Inflammation, Obesity, and Cardiac Dysfunction: Therapeutic and Molecular Approach

(2019) Omar Mohammed Amen et al.   Frontiers in Pharmacology

Tumor susceptibility gene 101 ameliorates endotoxin-induced cardiac dysfunction by enhancing Parkin-mediated mitophagy

(2019) Kobina Essandoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exercise induces TFEB expression and activity in skeletal muscle in a PGC-1α-dependent manner

(2018) Avigail T. Erlich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

BNIP3L/NIX-dependent mitophagy regulates cell differentiation via metabolic reprogramming

(2018) Lorena Esteban-Martínez et al.   Autophagy

Pathogenesis of cardiac ischemia reperfusion injury is associated with CK2α-disturbed mitochondrial homeostasis via suppression of FUNDC1-related mitophagy

(2018) Hao Zhou et al.   CELL DEATH AND DIFFERENTIATION

Beclin-1-Dependent Autophagy Protects the Heart During Sepsis

(2018) Yuxiao Sun et al.   CIRCULATION

Raising NAD in Heart Failure

(2018) Matthew A. Walker et al.   CIRCULATION

Correction to: Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy

(2018)   CIRCULATION

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Mst1 promotes cardiac ischemia–reperfusion injury by inhibiting the ERK-CREB pathway and repressing FUNDC1-mediated mitophagy

(2018) Wancheng Yu et al.   Journal of Physiological Sciences

Oxidation of Atg3 and Atg7 mediates inhibition of autophagy

(2018) Karen Frudd et al.   Nature Communications

Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease

(2018) Md Fakruddin et al.   Cell Reports

Ubiquitin-Dependent Degradation of Mitochondrial Proteins Regulates Energy Metabolism

(2018) Julie Lavie et al.   Cell Reports

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

(2018) Gian-Luca McLelland et al.   eLife

Mitochondrial dysfunction in pathophysiology of heart failure

(2018) Bo Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac-specific Conditional Knockout of the 18-kDa Mitochondrial Translocator Protein Protects from Pressure Overload Induced Heart Failure

(2018) Phung N. Thai et al.   Scientific Reports

Inhibiting Receptor of Advanced Glycation End Products Attenuates Pressure Overload-Induced Cardiac Dysfunction by Preventing Excessive Autophagy

(2018) Wenbin Gao et al.   Frontiers in Physiology

Autophagy and aging: Maintaining the proteome through exercise and caloric restriction

(2018) Kurt A. Escobar et al.   AGING CELL

Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space

(2018) Katharina Weinhäupl et al.   CELL

A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity

(2018) Yanjun Li et al.   EMBO JOURNAL

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

(2018) Toshiro Saito et al.   JOURNAL OF CLINICAL INVESTIGATION

Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury

(2018) Chengjun Hu et al.   JOURNAL OF CLINICAL INVESTIGATION

Evolving and Expanding the Roles of Mitophagy as a Homeostatic and Pathogenic Process

(2018) Åsa B. Gustafsson et al.   PHYSIOLOGICAL REVIEWS

Dysfunction of mitochondrial Lon protease and identification of oxidized protein in mouse brain following exposure to MPTP: Implications for Parkinson disease

(2017) Anne-Laure Bulteau et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

(2017) Pedro M. Quirós et al.   JOURNAL OF CELL BIOLOGY

Inflammasome activation and assembly at a glance

(2017) Ankit Malik et al.   JOURNAL OF CELL SCIENCE

TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux

(2017) Bo Pan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cytosolic proteostasis through importing of misfolded proteins into mitochondria

(2017) Linhao Ruan et al.   NATURE

Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

(2017) Vincenzo Sorrentino et al.   NATURE

The mitochondrial UPR: mechanisms, physiological functions and implications in ageing

(2017) Tomer Shpilka et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance

(2017) Babette C. Hammerling et al.   Nature Communications

The 1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt Supplementation on Multi-Organ Markers of Oxidative Stress and Mitochondrial Function in Rats

(2017) Wesley Kephart et al.   Nutrients

Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging

(2017) Johnathan Labbadia et al.   Cell Reports

Ripk3 induces mitochondrial apoptosis via inhibition of FUNDC1 mitophagy in cardiac IR injury

(2017) Hao Zhou et al.   Redox Biology

An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers

(2017) Sophia E. Airhart et al.   PLoS One

Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts

(2016) Ying Ann Chiao et al.   Aging-US

Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance

(2016) Allen M. Andres et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response

(2016) Hyun-Eui Kim et al.   CELL

Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis

(2016) Kristen M. Berendzen et al.   CELL

Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation

(2016) Diana Matheoud et al.   CELL

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

(2016) Zhenyu Zhong et al.   CELL

Homeostatic Responses Regulate Selfish Mitochondrial Genome Dynamics in C. elegans

(2016) Bryan L. Gitschlag et al.   Cell Metabolism

Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response

(2016) Li-Wa Shao et al.   CELL RESEARCH

Response by Shirakabe et al to Letter Regarding Article, “Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart Failure”

(2016) Akihiro Shirakabe et al.   CIRCULATION

Normalization of NAD+Redox Balance as a Therapy for Heart FailureClinical Perspective

(2016) Chi Fung Lee et al.   CIRCULATION

The Failing Heart Relies on Ketone Bodies as a Fuel

(2016) Gregory Aubert et al.   CIRCULATION

ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the HeartNovelty and Significance

(2016) Jung-Kang Jin et al.   CIRCULATION RESEARCH

The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR

(2016) Christopher J. Fiorese et al.   CURRENT BIOLOGY

CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels

(2016) Karolina Szczepanowska et al.   EMBO JOURNAL

Impaired Nrf2 regulation of mitochondrial biogenesis in rostral ventrolateral medulla on hypertension induced by systemic inflammation

(2016) Kay L.H. Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system

(2016) Gian-Luca McLelland et al.   JOURNAL OF CELL BIOLOGY

Nuclear factor erythroid-derived 2-like 2 (NFE2L2, Nrf2) mediates exercise-induced mitochondrial biogenesis and the anti-oxidant response in mice

(2016) Troy L. Merry et al.   JOURNAL OF PHYSIOLOGY-LONDON

Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system

(2016) Virgilio J. J. Cadete et al.   JOURNAL OF PHYSIOLOGY-LONDON

Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process

(2016) Giovanna Cenini et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation

(2016) Eisuke Itakura et al.   MOLECULAR CELL

Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation

(2016) Christian Münch et al.   NATURE

Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

(2016) Yi-Fan Lin et al.   NATURE

Correcting mitochondrial fusion by manipulating mitofusin conformations

(2016) Antonietta Franco et al.   NATURE

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

(2016) Dongryeol Ryu et al.   NATURE MEDICINE

Cardioprotection and lifespan extension by the natural polyamine spermidine

(2016) Tobias Eisenberg et al.   NATURE MEDICINE

Role of Carbonyl Modifications on Aging-Associated Protein Aggregation

(2016) Maya Tanase et al.   Scientific Reports

Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats

(2016) Csilla Ari et al.   Frontiers in Molecular Neuroscience

Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways

(2015) Yuko Hirota et al.   Autophagy

Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease

(2015) S. Hwang et al.   EMBO Molecular Medicine

Genetically induced moderate inhibition of 20S proteasomes in cardiomyocytes facilitates heart failure in mice during systolic overload

(2015) Mark J. Ranek et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial and Nuclear Accumulation of the Transcription Factor ATFS-1 Promotes OXPHOS Recovery during the UPRmt

(2015) Amrita M. Nargund et al.   MOLECULAR CELL

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

(2015) Konstantinos Palikaras et al.   NATURE

A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death

(2015) Xiaowen Wang et al.   NATURE

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

(2015) Lidia Wrobel et al.   NATURE

Retro-translocation of mitochondrial intermembrane space proteins

(2015) Piotr Bragoszewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration

(2015) Daniel A. Stevens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Time-restricted feeding attenuates age-related cardiac decline in Drosophila

(2015) S. Gill et al.   SCIENCE

Mitochondrial function in neuronal cells depends on p97/VCP/Cdc48-mediated quality control

(2015) Lei Fang et al.   Frontiers in Cellular Neuroscience

PGC-1α modulates denervation-induced mitophagy in skeletal muscle

(2015) Anna Vainshtein et al.   Skeletal Muscle

Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart

(2014) Dao-Fu Dai et al.   AGING CELL

TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control

(2014) Jemma Gatliff et al.   Autophagy

Oxidative Post-Translational Modifications Develop LONP1 Dysfunction in Pressure Overload Heart Failure

(2014) Atsushi Hoshino et al.   Circulation-Heart Failure

Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control

(2014) Gian-Luca McLelland et al.   EMBO JOURNAL

Quality control of oxidatively damaged mitochondrial proteins is mediated by p97 and the proteasome

(2014) Charles Hemion et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy

(2014) Guo Chen et al.   MOLECULAR CELL

Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling

(2014) Rimpy Dhingra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Late-life rapamycin treatment reverses age-related heart dysfunction

(2013) James M. Flynn et al.   AGING CELL

PINK1 is degraded through the N-end rule pathway

(2013) Koji Yamano et al.   Autophagy

Protective role of PARK2/Parkin in sepsis-induced cardiac contractile and mitochondrial dysfunction

(2013) Jérôme Piquereau et al.   Autophagy

The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria

(2013) Seok Min Jin et al.   Autophagy

Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Phosphorylation by Protein Kinase Cδ (PKCδ) Inhibits Mitochondria Elimination by Lysosomal-like Structures following Ischemia and Reoxygenation-induced Injury

(2013) Gouri Yogalingam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ubiquitin-Proteasome System Regulates Mitochondrial Intermembrane Space Proteins

(2013) P. Bragoszewski et al.   MOLECULAR AND CELLULAR BIOLOGY

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

(2013) Shireen A. Sarraf et al.   NATURE

AMP Activated Protein Kinase Is Indispensable for Myocardial Adaptation to Caloric Restriction in Mice

(2013) Kai Chen et al.   PLoS One

Loss of PINK1 Increases the Heart's Vulnerability to Ischemia-Reperfusion Injury

(2013) Hilary K. Siddall et al.   PLoS One

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Substrate- and Isoform-Specific Proteome Stability in Normal and Stressed Cardiac Mitochondria

(2012) Edward Lau et al.   CIRCULATION RESEARCH

A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

(2012) Vincent Soubannier et al.   CURRENT BIOLOGY

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

(2012) Andrew W Greene et al.   EMBO REPORTS

Parkin Protein Deficiency Exacerbates Cardiac Injury and Reduces Survival following Myocardial Infarction

(2012) Dieter A. Kubli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Voltage-dependent Anion Channels (VDACs) Recruit Parkin to Defective Mitochondria to Promote Mitochondrial Autophagy

(2012) Yu Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

(2012) Yoshihiro Kashiwaya et al.   NEUROBIOLOGY OF AGING

Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo

(2012) Vincent Soubannier et al.   PLoS One

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

(2012) A. M. Nargund et al.   SCIENCE

PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease

(2011) Joo-Ho Shin et al.   CELL

Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation

(2011) Mariusz Karbowski et al.   CURRENT OPINION IN CELL BIOLOGY

Caloric Restriction Ameliorates Angiotensin II–Induced Mitochondrial Remodeling and Cardiac Hypertrophy

(2011) Piet Finckenberg et al.   HYPERTENSION

Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

(2011) Fanjun Meng et al.   Molecular Neurodegeneration

PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

(2011) F. Billia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sustained Activation of Nuclear Erythroid 2-Related Factor 2/Antioxidant Response Element Signaling Promotes Reductive Stress in the Human Mutant Protein Aggregation Cardiomyopathy in Mice

(2010) Namakkal Soorappan Rajasekaran et al.   ANTIOXIDANTS & REDOX SIGNALING

Ubiquitin Proteasome Dysfunction in Human Hypertrophic and Dilated Cardiomyopathies

(2010) Jaime M. Predmore et al.   CIRCULATION

Vps35 Mediates Vesicle Transport between the Mitochondria and Peroxisomes

(2010) Emélie Braschi et al.   CURRENT BIOLOGY

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Degradation of an intramitochondrial protein by the cytosolic proteasome

(2010) V. Azzu et al.   JOURNAL OF CELL SCIENCE

4-Hydroxy-2-nonenal protects against cardiac ischemia–reperfusion injury via the Nrf2-dependent pathway

(2010) Yan Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover

(2010) Shan Xu et al.   MOLECULAR BIOLOGY OF THE CELL

Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy

(2010) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Pruning by Nix and BNip3: An Essential Function for Cardiac-Expressed Death Factors

(2010) Gerald W. Dorn   Journal of Cardiovascular Translational Research

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Nrf2 Protects Against Maladaptive Cardiac Responses to Hemodynamic Stress

(2009) Jinqing Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of BNIP3 and NIX in cell death, autophagy and mitophagy

(2009) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Mitochondrial Protein Quality Control by the Proteasome Involves Ubiquitination and the Protease Omi

(2008) Susanne Radke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE

The amyloid  -peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

(2008) C. A. Hansson Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA