Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling

The pore-lining regions in cytochrome c oxidases: A computational analysis of caveolin, cholesterol and transmembrane helix contributions to proton movement

(2014) Gene A. Morrill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Catching broken hearts: pre-clinical detection of doxorubicin and trastuzumab mediated cardiac dysfunction in the breast cancer setting

(2014) Mahwash F. Saeed et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

P53 inhibition exacerbates late-stage anthracycline cardiotoxicity

(2014) Wuqiang Zhu et al.   CARDIOVASCULAR RESEARCH

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

(2014) Yoshihiko Ichikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

(2014) Tomáš Šimůnek et al.   Pharmacological Reports

Emerging Paradigms in Cardiomyopathies Associated With Cancer Therapies

(2013) Bonnie Ky et al.   CIRCULATION RESEARCH

Bidirectional Regulation of Nuclear Factor-κB and Mammalian Target of Rapamycin Signaling Functionally Links Bnip3 Gene Repression and Cell Survival of Ventricular Myocytes

(2013) Rimpy Dhingra et al.   Circulation-Heart Failure

p53 Mediates Autophagy and Cell Death by a Mechanism Contingent On Bnip3

(2013) Erika Yan Wang et al.   HYPERTENSION

Mst-1 switches between cardiac cell life and death

(2013) Rimpy Dhingra et al.   NATURE MEDICINE

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

(2013) Yasuhiro Maejima et al.   NATURE MEDICINE

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

(2012) Subir K. Roy Chowdhury et al.   BRAIN

The permeability transition pore as a Ca2+ release channel: New answers to an old question

(2012) Paolo Bernardi et al.   CELL CALCIUM

Striking a Balance: Autophagy, Apoptosis, and Necrosis in a Normal and Failing Heart

(2012) Wajihah Mughal et al.   CURRENT HYPERTENSION REPORTS

Bax regulates primary necrosis through mitochondrial dynamics

(2012) R. S. Whelan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins

(2012) Ryan J. Mailloux et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A Novel Hypoxia-Inducible Spliced Variant of Mitochondrial Death Gene Bnip3 Promotes Survival of Ventricular Myocytes

(2011) Hongying Gang et al.   CIRCULATION RESEARCH

The Cardioprotective Role of Probucol Against Anthracycline and Trastuzumab-Mediated Cardiotoxicity

(2011) Jonathan R. Walker et al.   JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

Bnip3 as a Dual Regulator of Mitochondrial Turnover and Cell Death in the Myocardium

(2011) Åsa B. Gustafsson   PEDIATRIC CARDIOLOGY

High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria

(2011) George W. Rogers et al.   PLoS One

The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms

(2010) Thomas Landes et al.   EMBO REPORTS

Is Autophagy in Response to Ischemia and Reperfusion Protective or Detrimental for the Heart?

(2010) Sebastiano Sciarretta et al.   PEDIATRIC CARDIOLOGY

Transcription Factor GATA4 Inhibits Doxorubicin-induced Autophagy and Cardiomyocyte Death

(2009) Satoru Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Utility of Tissue Doppler and Strain Rate Imaging in the Early Detection of Trastuzumab and Anthracycline Mediated Cardiomyopathy

(2009) Davinder S. Jassal et al.   JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

Autophagy in Load-Induced Heart Disease

(2008) Beverly A. Rothermel et al.   CIRCULATION RESEARCH

Antagonism of E2F-1 regulated Bnip3 transcription by NF- B is essential for basal cell survival

(2008) J. Shaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cell Cycle Factor E2F-1 Activates Bnip3 and the Intrinsic Death Pathway in Ventricular Myocytes

(2007) Natalia Yurkova et al.   CIRCULATION RESEARCH