Astroglia and Tau: New Perspectives

Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy

(2020) Isidro Ferrer et al.   ACTA NEUROPATHOLOGICA

Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates

(2020) Helen Ling et al.   ACTA NEUROPATHOLOGICA

Language and spatial dysfunction in Alzheimer disease with white matter thorn-shaped astrocytes

(2020) Elisa de Paula França Resende et al.   NEUROLOGY

A walk through tau therapeutic strategies

(2019) Santosh Jadhav et al.   Acta Neuropathologica Communications

Astrocytes usurp neurons as a disease focus

(2019) Shane A. Liddelow et al.   NATURE NEUROSCIENCE

Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules

(2019) Benjamin Falcon et al.   NATURE

Are comorbidities compatible with a molecular pathological classification of neurodegenerative diseases?

(2019) Gabor G. Kovacs   CURRENT OPINION IN NEUROLOGY

Chronic Traumatic Encephalopathy (CTE) Is Absent From a European Community-Based Aging Cohort While Cortical Aging-Related Tau Astrogliopathy (ARTAG) Is Highly Prevalent

(2019) Shelley L Forrest et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Extracellular Monomeric Tau Is Internalized by Astrocytes

(2019) Juan Ramón Perea et al.   Frontiers in Neuroscience

Cellular and regional vulnerability in frontotemporal tauopathies

(2019) Shelley L. Forrest et al.   ACTA NEUROPATHOLOGICA

Association between contact sports participation and chronic traumatic encephalopathy: a retrospective cohort study

(2019) Kevin F. Bieniek et al.   BRAIN PATHOLOGY

Four-repeat tauopathies

(2019) Thomas W. Rösler et al.   PROGRESS IN NEUROBIOLOGY

Relevance of host tau in tau seeding and spreading in tauopathies

(2019) Isidro Ferrer et al.   BRAIN PATHOLOGY

Molecular pathology of neurodegenerative diseases: principles and practice

(2019) Gabor G Kovacs   JOURNAL OF CLINICAL PATHOLOGY

Astroglial contribution to tau-dependent neurodegeneration

(2019) Marta Sidoryk-Węgrzynowicz et al.   BIOCHEMICAL JOURNAL

Astrocytic Tau Deposition Is Frequent in Typical and Atypical Alzheimer Disease Presentations

(2019) Amber Nolan et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Are mutations in MAPT associated with GGT type III?

(2019) S. L. Forrest et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Non-Alzheimer’s contributions to dementia and cognitive resilience in The 90+ Study

(2018) John L. Robinson et al.   ACTA NEUROPATHOLOGICA

Aging-related tau astrogliopathy (ARTAG): not only tau phosphorylation in astrocytes

(2018) Isidro Ferrer et al.   BRAIN PATHOLOGY

Tau filaments in neurodegenerative diseases

(2018) Michel Goedert   FEBS LETTERS

The Neurotoxic Role of Extracellular Tau Protein

(2018) Álvaro Sebastián-Serrano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain

(2018) Gabor G. Kovacs et al.   Acta Neuropathologica Communications

Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy

(2018) Mariet Allen et al.   ACTA NEUROPATHOLOGICA

Structures of filaments from Pick’s disease reveal a novel tau protein fold

(2018) Benjamin Falcon et al.   NATURE

Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold

(2018) Benjamin Falcon et al.   ACTA NEUROPATHOLOGICA

Spectrum of tau pathologies in Huntington’s disease

(2018) Swikrity Upadhyay Baskota et al.   LABORATORY INVESTIGATION

Presence of tau astrogliopathy in frontotemporal dementia caused by a novel Grn nonsense (Trp2*) mutation

(2018) Estrella Gómez-Tortosa et al.   NEUROBIOLOGY OF AGING

Reduced gliotransmitter release from astrocytes mediates tau-induced synaptic dysfunction in cultured hippocampal neurons

(2017) Roberto Piacentini et al.   GLIA

Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG)

(2017) Gabor G. Kovacs et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases

(2017) Gabor G. Kovacs et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain

(2017) Sneha Narasimhan et al.   JOURNAL OF NEUROSCIENCE

The release and trans-synaptic transmission of Tau via exosomes

(2017) Yipeng Wang et al.   Molecular Neurodegeneration

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Clinicopathologic heterogeneity in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) due to microtubule-associated protein tau (MAPT) p.P301L mutation, including a patient with globular glial tauopathy

(2017) P. Tacik et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Connexin-43 and aquaporin-4 are markers of ageing-related tau astrogliopathy (ARTAG)-related astroglial response

(2017) G. G. Kovacs et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

What is the evidence that tau pathology spreads through prion-like propagation?

(2017) Amrit Mudher et al.   Acta Neuropathologica Communications

Neuropathological criteria of anti-IgLON5-related tauopathy

(2016) Ellen Gelpi et al.   ACTA NEUROPATHOLOGICA

The ordered assembly of tau is the gain-of-toxic function that causes human tauopathies

(2016) Michel Goedert   Alzheimers & Dementia

Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration

(2016) Michel Goedert et al.   BRAIN

Astrogliopathy predominates the earliest stage of corticobasal degeneration pathology

(2016) Helen Ling et al.   BRAIN

Tau pathology in Creutzfeldt-Jakob disease revisited

(2016) Gabor G. Kovacs et al.   BRAIN PATHOLOGY

17q21.31 duplication causes prominent tau-related dementia with increased MAPT expression

(2016) K Le Guennec et al.   MOLECULAR PSYCHIATRY

Familial early-onset dementia with complex neuropathologic phenotype and genomic background

(2016) John Alexander et al.   NEUROBIOLOGY OF AGING

Incidental corticobasal degeneration

(2016) A. Martínez-Maldonado et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Mechanisms of Aβ Clearance and Degradation by Glial Cells

(2016) Miriam Ries et al.   Frontiers in Aging Neuroscience

ARTAG in the basal forebrain: widening the constellation of astrocytic tau pathology

(2016) Alan King Lun Liu et al.   Acta Neuropathologica Communications

A novel tau mutation, p.K317N, causes globular glial tauopathy

(2015) Pawel Tacik et al.   ACTA NEUROPATHOLOGICA

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

(2015) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy

(2015) Ann C. McKee et al.   ACTA NEUROPATHOLOGICA

The Neuropathology of Chronic Traumatic Encephalopathy

(2015) Ann C. McKee et al.   BRAIN PATHOLOGY

The Relationship Between Development of Neuronal and Astrocytic Tau Pathologies in Subcortical Nuclei and Progression of Argyrophilic Grain Disease

(2015) Chikako Ikeda et al.   BRAIN PATHOLOGY

Familial Behavioral Variant Frontotemporal Dementia Associated With Astrocyte-Predominant Tauopathy

(2015) Isidre Ferrer et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders?

(2015) Benjamin Ettle et al.   MOLECULAR NEUROBIOLOGY

Spreading of pathology in neurodegenerative diseases: a focus on human studies

(2015) Johannes Brettschneider et al.   NATURE REVIEWS NEUROSCIENCE

Invited review: Frontotemporal dementia caused bymicrotubule-associated protein taugene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

(2015) Bernardino Ghetti et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Invited review: Neuropathology of tauopathies: principles and practice

(2015) G. G. Kovacs   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brains

(2014) Susana Boluda et al.   ACTA NEUROPATHOLOGICA

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Patterns of Hippocampal Tau Pathology Differentiate Neurodegenerative Dementias

(2014) Ivan Milenkovic et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies

(2014) David W. Sanders et al.   NEURON

Astrocytic inclusions in progressive supranuclear palsy and corticobasal degeneration

(2014) Mari Yoshida   NEUROPATHOLOGY

Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein

(2014) Simon Dujardin et al.   PLoS One

Transcellular degradation of axonal mitochondria

(2014) Chung-ha O. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevalence of mixed pathologies in the aging brain

(2014) Jasmin Rahimi et al.   Alzheimers Research & Therapy

Globular glial tauopathies (GGT): consensus recommendations

(2013) Zeshan Ahmed et al.   ACTA NEUROPATHOLOGICA

Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series

(2013) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

Physiological release of endogenous tau is stimulated by neuronal activity

(2013) Amy M Pooler et al.   EMBO REPORTS

Glial and Neuronal Tau Pathology in Tauopathies

(2013) Isidre Ferrer et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Tau pathology and neurodegeneration

(2013) Maria Grazia Spillantini et al.   LANCET NEUROLOGY

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

(2013) Won-Suk Chung et al.   NATURE

TARDBPmutation p.Ile383Val associated with semantic dementia and complex proteinopathy

(2013) E. Gelpi et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The unfolded protein response in Alzheimer’s disease

(2013) Víctor Hugo Cornejo et al.   Seminars in Immunopathology

The spectrum of disease in chronic traumatic encephalopathy

(2012) Ann C. McKee et al.   BRAIN

Incidental corticobasal degeneration in a 76-year-old woman

(2012) Ivan Milenkovic et al.   CLINICAL NEUROPATHOLOGY

Mesial Temporal Astrocyte Tau Pathology in the MRC-CFAS Ageing Brain Cohort

(2012) G. Lace et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Neuropathology of the hippocampus in FTLD-Tau with Pick bodies: a study of the BrainNet Europe Consortium

(2012) G. G. Kovacs et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

A peculiar constellation of tau pathology defines a subset of dementia in the elderly

(2011) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease

(2011) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Alzheimer's Disease: Redox Dysregulation As a Common Denominator for Diverse Pathogenic Mechanisms

(2011) Rommy von Bernhardi et al.   ANTIOXIDANTS & REDOX SIGNALING

Perivascular orientation of astrocytic plaques and tuft-shaped astrocytes

(2011) Katsuhiko Shibuya et al.   BRAIN RESEARCH

Removing Protein Aggregates: The Role of Proteolysis in Neurodegeneration

(2011) D. A.T. Nijholt et al.   CURRENT MEDICINAL CHEMISTRY

In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice

(2011) K. Yamada et al.   JOURNAL OF NEUROSCIENCE

TDP-43 pathology in primary progressive aphasia and frontotemporal dementia with pathologic Alzheimer disease

(2010) Eileen H. Bigio et al.   ACTA NEUROPATHOLOGICA

Neuropathology of variants of progressive supranuclear palsy

(2010) Dennis W Dickson et al.   CURRENT OPINION IN NEUROLOGY

Cell-Mediated Neuroprotection in a Mouse Model of Human Tauopathy

(2010) D. W. Hampton et al.   JOURNAL OF NEUROSCIENCE

Degeneration in Different Parkinsonian Syndromes Relates to Astrocyte Type and Astrocyte Protein Expression

(2009) Yun Ju C. Song et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia

(2008) Marsel Mesulam et al.   ANNALS OF NEUROLOGY

Delineation of Early Changes in Cases with Progressive Supranuclear Palsy-Like Pathology. Astrocytes in Striatum are Primary Targets of Tau Phosphorylation and GFAP Oxidation

(2008) Gabriel Santpere et al.   BRAIN PATHOLOGY

Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience

(2008) Gabor G. Kovacs et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain

(2008) J.E. Simpson et al.   NEUROBIOLOGY OF AGING