Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53- deficiency-driven castration-resistant prostate cancer

Published 2016 View Full Article

Authors

Keywords

Warburg effect, Autophagy, PTEN, TP53, Hexokinase 2, AMPK, ULK-1, MCL-1, 2-Deoxy-glucose, Chloroquine, Androgen receptor, Castration-resistant prostate cancer, Genetically-engineered mouse model

Journal

EBioMedicine

Volume 7, Issue -, Pages 50-61

Publisher

Elsevier BV

Online

2016-03-20

DOI

10.1016/j.ebiom.2016.03.022

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