Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2’-O-Methylation of Viral RNA
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Title
Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2’-O-Methylation of Viral RNA
Authors
Keywords
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Journal
Viruses-Basel
Volume 12, Issue 5, Pages 525
Publisher
MDPI AG
Online
2020-05-11
DOI
10.3390/v12050525
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Note: Only part of the references are listed.- Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity
- (2020) Sara Verdura et al. Aging-US
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- (2020) Miguel Angel Martinez ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2020) Shuai Xia et al. Cellular & Molecular Immunology
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- (2020) G. Kampf et al. JOURNAL OF HOSPITAL INFECTION
- The neuroinvasive potential of SARS‐CoV2 may be at least partially responsible for the respiratory failure of COVID‐19 patients
- (2020) Yan‐Chao Li et al. JOURNAL OF MEDICAL VIROLOGY
- Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection
- (2020) Jianhua Xia et al. JOURNAL OF MEDICAL VIROLOGY
- AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells
- (2020) Maria L. Lotsberg et al. Journal of Thoracic Oncology
- Baricitinib as potential treatment for 2019-nCoV acute respiratory disease
- (2020) Peter Richardson et al. LANCET
- Can we contain the COVID-19 outbreak with the same measures as for SARS?
- (2020) Annelies Wilder-Smith et al. LANCET INFECTIOUS DISEASES
- A new coronavirus associated with human respiratory disease in China
- (2020) Fan Wu et al. NATURE
- Coronavirus puts drug repurposing on the fast track
- (2020) Charlotte Harrison NATURE BIOTECHNOLOGY
- Responding to Covid-19 — A Once-in-a-Century Pandemic?
- (2020) Bill Gates NEW ENGLAND JOURNAL OF MEDICINE
- Clinical Characteristics of Coronavirus Disease 2019 in China
- (2020) Wei-jie Guan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
- (2020) Qun Li et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2
- (2020) Renhong Yan et al. SCIENCE
- Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
- (2020) Timothy P. Sheahan et al. Nature Communications
- Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
- (2020) Jasper Fuk-Woo Chan et al. Emerging Microbes & Infections
- Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
- (2020) Canrong Wu et al. Acta Pharmaceutica Sinica B
- Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic Mechanisms
- (2020) Abdul Mannan Baig et al. ACS Chemical Neuroscience
- The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes
- (2020) Elisabet Cuyàs et al. Aging-US
- Of chloroquine and COVID-19
- (2020) Franck Touret et al. ANTIVIRAL RESEARCH
- COVID-19 infection and rheumatoid arthritis: Faraway, so close!
- (2020) Ennio Giulio Favalli et al. AUTOIMMUNITY REVIEWS
- Nervous system involvement after infection with COVID-19 and other coronaviruses
- (2020) Yeshun Wu et al. BRAIN BEHAVIOR AND IMMUNITY
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
- (2020) Alexandra C. Walls et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- The Variety of Cardiovascular Presentations of COVID-19
- (2020) Justin A. Fried et al. CIRCULATION
- In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
- (2020) Xueting Yao et al. CLINICAL INFECTIOUS DISEASES
- New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
- (2020) Christian A. Devaux et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
- (2020) Philippe Gautret et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis
- (2020) Jing Yang et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression
- (2020) Dan Zhou et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Clinical and immunological features of severe and moderate coronavirus disease 2019
- (2020) Guang Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- SARS-CoV-2: a storm is raging
- (2020) Savannah F. Pedersen et al. JOURNAL OF CLINICAL INVESTIGATION
- Phase I, Open-Label, Dose-Escalation/Dose-Expansion Study of Lifirafenib (BGB-283), an RAF Family Kinase Inhibitor, in Patients With Solid Tumors
- (2020) Jayesh Desai et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2020) Huan Han et al. JOURNAL OF MEDICAL VIROLOGY
- Novel coronavirus treatment with ribavirin: Groundwork for an evaluation concerning COVID-19
- (2020) Jahan S. Khalili et al. JOURNAL OF MEDICAL VIROLOGY
- TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib
- (2020) Dandan Wu et al. JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
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- (2020) Fei Zhou et al. LANCET
- COVID-19: consider cytokine storm syndromes and immunosuppression
- (2020) Puja Mehta et al. LANCET
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
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- (2020) Suhas Srinivasan et al. Viruses-Basel
- Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
- (2020) Yadi Zhou et al. Cell Discovery
- Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
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- (2019) Allison L. Totura et al. Expert Opinion on Drug Discovery
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- (2019) Gloria E. Villalpando-Rodriguez et al. Oxidative Medicine and Cellular Longevity
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- (2019) Korneev et al. Viruses-Basel
- Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials
- (2019) Alexander Drilon et al. LANCET ONCOLOGY
- Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials
- (2019) Robert C Doebele et al. LANCET ONCOLOGY
- SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection
- (2019) Nils C. Gassen et al. Nature Communications
- Evaluation of Clinical Cardiac Safety of Itacitinib, a JAK1 Inhibitor, in Healthy Participants
- (2019) Xiaohua Gong et al. Clinical Pharmacology in Drug Development
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- (2018) Moyi Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2018) Jeanne M. Sisk et al. JOURNAL OF GENERAL VIROLOGY
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- (2018) Anna Tesei et al. Frontiers in Pharmacology
- Cytokine release syndrome
- (2018) Alexander Shimabukuro-Vornhagen et al. Journal for ImmunoTherapy of Cancer
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- (2018) Stewart J. Tepper HEADACHE
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- (2018) Verónica Ruiz-Torres et al. Marine Drugs
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- (2018) Benny Zhitomirsky et al. Cell Death & Disease
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- (2017) et al. MOLECULES
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- DrugBank 5.0: a major update to the DrugBank database for 2018
- (2017) David S Wishart et al. NUCLEIC ACIDS RESEARCH
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- (2017) François Ferron et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2017) Timothy P. Sheahan et al. Science Translational Medicine
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- (2017) Patrick P.C. Boor et al. Translational Research
- Virus inactivation under the photodynamic effect of phthalocyanine zinc(II) complexes
- (2017) Mimi Remichkova et al. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
- Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas
- (2017) Sachin Jain et al. OncoTargets and Therapy
- Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1)
- (2017) Alexander Drilon et al. Cancer Discovery
- Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses
- (2017) Laurent Meertens et al. Cell Reports
- Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay
- (2016) Mizuki Yamamoto et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 1
- (2016) Jason G. Kettle et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- The safety and efficacy of sonidegib for the treatment of locally advanced basal cell carcinoma
- (2016) Nicholas J. Collier et al. Expert Review of Anticancer Therapy
- Calculating protein-ligand binding affinities with MMPBSA: Method and error analysis
- (2016) Changhao Wang et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- A randomized, double-blind, placebo-controlled, dose-escalation study of the safety and efficacy of INCB039110, an oral janus kinase 1 inhibitor, in patients with stable, chronic plaque psoriasis
- (2016) Robert Bissonnette et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion
- (2016) Christopher M. Coleman et al. JOURNAL OF VIROLOGY
- Janus kinase (JAK) inhibitors in the treatment of inflammatory and neoplastic diseases
- (2016) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Regulation of Stress Responses and Translational Control by Coronavirus
- (2016) To Fung et al. Viruses-Basel
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- (2016) S Ma et al. Cell Death & Disease
- Protease inhibitors targeting coronavirus and filovirus entry
- (2015) Yanchen Zhou et al. ANTIVIRAL RESEARCH
- In vitro combinations containing Tegobuvir are highly efficient in curing cells from HCV replicon and in delaying/preventing the development of drug resistance
- (2015) Inge Vliegen et al. ANTIVIRAL RESEARCH
- The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds
- (2015) Yahira M. Báez-Santos et al. ANTIVIRAL RESEARCH
- Novel oxazolidinone calcitonin gene-related peptide (CGRP) receptor antagonists for the acute treatment of migraine
- (2015) Brendan M. Crowley et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Sonidegib: First Global Approval
- (2015) Celeste B. Burness DRUGS
- The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
- (2015) Samuel Genheden et al. Expert Opinion on Drug Discovery
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- (2015) Jennifer L. Hyde et al. VIROLOGY
- Yeast-based assays for the high-throughput screening of inhibitors of coronavirus RNA cap guanine-N7-methyltransferase
- (2014) Ying Sun et al. ANTIVIRAL RESEARCH
- Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation
- (2014) Marie Stampe Ostenfeld et al. Autophagy
- YASARA View—molecular graphics for all devices—from smartphones to workstations
- (2014) Elmar Krieger et al. BIOINFORMATICS
- Structure-Based Virtual Screening for Drug Discovery: Principles, Applications and Recent Advances
- (2014) Evanthia Lionta et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- All-oral combination of ledipasvir, vedroprevir, tegobuvir, and ribavirin in treatment-naïve patients with genotype 1 HCV infection
- (2014) David L. Wyles et al. HEPATOLOGY
- Attenuation and Restoration of Severe Acute Respiratory Syndrome Coronavirus Mutant Lacking 2'-O-Methyltransferase Activity
- (2014) V. D. Menachery et al. JOURNAL OF VIROLOGY
- Correction: In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation
- (2014) Mickaël Bouvet et al. PLoS Pathogens
- Coronavirus infection, ER stress, apoptosis and innate immunity
- (2014) To S. Fung et al. Frontiers in Microbiology
- Antiviral Activity, Pharmacokinetics, and Safety of the HIV-1 Protease Inhibitor TMC310911, Coadministered With Ritonavir, in Treatment-Naive HIV-1–Infected Patients
- (2013) Hans-Jürgen Stellbrink et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Structure-Function Analysis of Severe Acute Respiratory Syndrome Coronavirus RNA Cap Guanine-N7-Methyltransferase
- (2013) Y. Chen et al. JOURNAL OF VIROLOGY
- Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP
- (2013) Xu Jin et al. VIRUS RESEARCH
- The HCV Non-Nucleoside Inhibitor Tegobuvir Utilizes a Novel Mechanism of Action to Inhibit NS5B Polymerase Function
- (2012) Christy M. Hebner et al. PLoS One
- Short peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2′-O-methyltransferase activity of nsp10/nsp16 complex
- (2012) Min Ke et al. VIRUS RESEARCH
- Brain neuropeptides in central ventilatory and cardiovascular regulation in trout
- (2012) Jean-Claude Le Mével et al. Frontiers in Endocrinology
- Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine
- (2011) David J Hewitt et al. CEPHALALGIA
- Systematic Approaches towards the Development of Host-Directed Antiviral Therapeutics
- (2011) Andrew Prussia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Chloroquine inhibits glutamate-induced death of a neuronal cell line by reducing reactive oxygen species through sigma-1 receptor
- (2011) Yoko Hirata et al. JOURNAL OF NEUROCHEMISTRY
- Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain
- (2011) K. Ahn et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- An Anti-Inflammatory Role of VEGFR2/Src Kinase Inhibitor in Herpes Simplex Virus 1-Induced Immunopathology
- (2011) S. Sharma et al. JOURNAL OF VIROLOGY
- 2 methylate or not 2 methylate: viral evasion of the type I interferon response
- (2011) Adolfo García-Sastre NATURE IMMUNOLOGY
- Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
- (2011) Roland Züst et al. NATURE IMMUNOLOGY
- Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex
- (2011) Yu Chen et al. PLoS Pathogens
- Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex
- (2011) Etienne Decroly et al. PLoS Pathogens
- R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
- (2010) S. J. Holland et al. CANCER RESEARCH
- Molecular Mapping of the RNA Cap 2′-O-Methyltransferase Activation Interface between Severe Acute Respiratory Syndrome Coronavirus nsp10 and nsp16
- (2010) Adrien Lugari et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ligand docking and binding site analysis with PyMOL and Autodock/Vina
- (2010) Daniel Seeliger et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- 2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
- (2010) Stephane Daffis et al. NATURE
- Discovery of MK-3207: A Highly Potent, Orally Bioavailable CGRP Receptor Antagonist
- (2010) Ian M. Bell et al. ACS Medicinal Chemistry Letters
- Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor
- (2010) Douglas S. Johnson et al. ACS Medicinal Chemistry Letters
- AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
- (2009) Oleg Trott et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway
- (2008) Hongliang Wang et al. CELL RESEARCH
- Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration
- (2008) Moorthy S. S. Palanki et al. JOURNAL OF MEDICINAL CHEMISTRY
- Molecular dynamic simulations analysis of ritronavir and lopinavir as SARS-CoV 3CLpro inhibitors
- (2008) Veena Nukoolkarn et al. JOURNAL OF THEORETICAL BIOLOGY
- Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2
- (2008) J. Netland et al. JOURNAL OF VIROLOGY
- Antifungal photodynamic therapy
- (2007) Ryan F. Donnelly et al. MICROBIOLOGICAL RESEARCH
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