Acute Phase Response as a Biological Mechanism‐of‐Action of (Nano)particle‐Induced Cardiovascular Disease

An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics

(2019) Ilias Angelidis et al.   Nature Communications

Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses

(2019) Niels Hadrup et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Exposure to air pollution inside electric and diesel-powered passenger trains

(2019) Maria Helena Guerra Andersen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Inflammatory and coagulatory markers and exposure to different size fractions of particle mass, number and surface area air concentrations in Swedish iron foundries, in particular respirable quartz

(2019) Håkan Westberg et al.   INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Health effects of exposure to diesel exhaust in diesel-powered trains

(2019) Maria Helena Guerra Andersen et al.   Particle and Fibre Toxicology

Airport emission particles: exposure characterization and toxicity following intratracheal instillation in mice

(2019) Katja Maria Bendtsen et al.   Particle and Fibre Toxicology

Association between a urinary biomarker for exposure to PAH and blood level of the acute phase protein serum amyloid A in coke oven workers

(2019) Niels Hadrup et al.   Environmental Health

Acute phase response and inflammation following pulmonary exposure to low doses of zinc oxide nanoparticles in mice

(2019) Niels Hadrup et al.   Nanotoxicology

Commentary: the chronic inhalation study in rats for assessing lung cancer risk may be better than its reputation

(2019) Anne T. Saber et al.   Particle and Fibre Toxicology

Pulmonary toxicity of Fe2O3, ZnFe2O4, NiFe2O4 and NiZnFe4O8 nanomaterials: Inflammation and DNA strand breaks

(2019) Niels Hadrup et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

(2019) Kenneth Klingenberg Barfod et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Effects of physicochemical properties of TiO2 nanomaterials for pulmonary inflammation, acute phase response and alveolar proteinosis in intratracheally exposed mice

(2019) Pernille Høgh Danielsen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Serum amyloid A3 is pro-atherogenic

(2018) Joel C. Thompson et al.   ATHEROSCLEROSIS

Toll-like receptor signalling induces the expression of serum amyloid A in epidermal keratinocytes and dermal fibroblasts

(2018) S. Morizane et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Assessment of polycyclic aromatic hydrocarbon exposure, lung function, systemic inflammation, and genotoxicity in peripheral blood mononuclear cells from firefighters before and after a work shift

(2018) Maria Helena Guerra Andersen et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Toxicity of pristine and paint-embedded TiO2 nanomaterials

(2018) AT Saber et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Editorial: dose-dependent ZnO particle-induced acute phase response in humans warrants re-evaluation of occupational exposure limits for metal oxides

(2018) Ulla Vogel et al.   Particle and Fibre Toxicology

Concentration-dependent systemic response after inhalation of nano-sized zinc oxide particles in human volunteers

(2018) Christian Monsé et al.   Particle and Fibre Toxicology

Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors

(2018) Magdolna Djurec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum amyloid A – a review

(2018) George H. Sack   MOLECULAR MEDICINE

Human nasal mucosal C-reactive protein responses after inhalation of ultrafine welding fume particles: positive correlation to systemic C-reactive protein responses

(2018) R. Baumann et al.   Nanotoxicology

Cardiovascular health effects following exposure of human volunteers during fire extinction exercises

(2017) Maria Helena Guerra Andersen et al.   Environmental Health

Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge

(2017) Vicki Stone et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Satellite-based estimates of long-term exposure to fine particulate matter are associated with C-reactive protein in 30 034 Taiwanese adults

(2017) Zilong Zhang et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Systemic serum amyloid A as a biomarker for exposure to zinc and/or copper-containing metal fumes

(2017) R Baumann et al.   Journal of Exposure Science and Environmental Epidemiology

Impact of Work Task-Related Acute Occupational Smoke Exposures on Select Proinflammatory Immune Parameters in Wildland Firefighters

(2017) Anna M. Adetona et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Association between polycyclic aromatic hydrocarbon exposure and peripheral blood mononuclear cell DNA damage in human volunteers during fire extinction exercises

(2017) Maria Helena Guerra Andersen et al.   MUTAGENESIS

Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection

(2017) Christine Sattler et al.   Particle and Fibre Toxicology

Multi-walled carbon nanotube-physicochemical properties predict the systemic acute phase response following pulmonary exposure in mice

(2017) Sarah S. Poulsen et al.   PLoS One

Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide

(2017) Stefan Bengtson et al.   PLoS One

Immunoproteasome dysfunction augments alternative polarization of alveolar macrophages

(2016) S Chen et al.   CELL DEATH AND DIFFERENTIATION

Occupational exposure levels of bioaerosol components are associated with serum levels of the acute phase protein Serum Amyloid A in greenhouse workers

(2016) Anne Mette Madsen et al.   Environmental Health

Inflammatory markers and exposure to airborne particles among workers in a Swedish pulp and paper mill

(2016) Håkan Westberg et al.   INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Surface area is the biologically most effective dose metric for acute nanoparticle toxicity in the lung

(2016) Otmar Schmid et al.   JOURNAL OF AEROSOL SCIENCE

Single and Combined Exposure to Zinc- and Copper-Containing Welding Fumes Lead to Asymptomatic Systemic Inflammation

(2016) Agnieszka Markert et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Toxicogenomics analysis of mouse lung responses following exposure to titanium dioxide nanomaterials reveal their disease potential at high doses

(2016) Luna Rahman et al.   MUTAGENESIS

Surface modification does not influence the genotoxic and inflammatory effects of TiO2nanoparticles after pulmonary exposure by instillation in mice

(2016) Håkan Wallin et al.   MUTAGENESIS

Multi-walled carbon nanotube physicochemical properties predict pulmonary inflammation and genotoxicity

(2016) Sarah S. Poulsen et al.   Nanotoxicology

IL-6, a central acute-phase mediator, as an early biomarker for exposure to zinc-based metal fumes

(2016) R. Baumann et al.   TOXICOLOGY

Metal fume fever and polymer fume fever

(2015) Michael I. Greenberg et al.   CLINICAL TOXICOLOGY

DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice

(2015) Zdenka O. Kyjovska et al.   MUTAGENESIS

Intratracheally instilled titanium dioxide nanoparticles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice

(2015) Mainul Husain et al.   Nanotoxicology

No involvement of alveolar macrophages in the initiation of carbon nanoparticle induced acute lung inflammation in mice

(2015) Shanze Chen et al.   Particle and Fibre Toxicology

Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition

(2015) Anne Thoustrup Saber et al.   Particle and Fibre Toxicology

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

(2015) Sarah S. Poulsen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease

(2015) Sarah S. Poulsen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A Cross-Sectional Study of the Cardiovascular Effects of Welding Fumes

(2015) Huiqi Li et al.   PLoS One

Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response

(2014) Sabina Halappanavar et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Associations of Short-Term Particle and Noise Exposures with Markers of Cardiovascular and Respiratory Health among Highway Maintenance Workers

(2014) Reto Meier et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A brief elevation of serum amyloid A is sufficient to increase atherosclerosis

(2014) Joel C. Thompson et al.   JOURNAL OF LIPID RESEARCH

Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease

(2014) Anne T. Saber et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Differential expression of C-Reactive protein and Serum amyloid A in different cell types in the lung tissue of chronic obstructive pulmonary disease patients

(2014) Carmen Calero et al.   BMC Pulmonary Medicine

Deficiency of Endogenous Acute Phase Serum Amyloid A Does Not Affect Atherosclerotic Lesions in Apolipoprotein E–Deficient Mice

(2013) Maria C. De Beer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Serum amyloid A stimulates macrophage foam cell formation via lectin-like oxidized low-density lipoprotein receptor 1 upregulation

(2013) Ha Young Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Immune Functions of Serum Amyloid A

(2013) Kari K. Eklund et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Assessment of the biological effects of welding fumes emitted from metal inert gas welding processes of aluminium and zinc-plated materials in humans

(2013) L. Hartmann et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Relationship Between Welding Fume Concentration and Systemic Inflammation After Controlled Exposure of Human Subjects With Welding Fumes From Metal Inert Gas Brazing of Zinc-Coated Materials

(2013) Peter Brand et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Particle-Induced Pulmonary Acute Phase Response Correlates with Neutrophil Influx Linking Inhaled Particles and Cardiovascular Risk

(2013) Anne Thoustrup Saber et al.   PLoS One

Transcriptomic Analysis Reveals Novel Mechanistic Insight into Murine Biological Responses to Multi-Walled Carbon Nanotubes in Lungs and Cultured Lung Epithelial Cells

(2013) Sarah Søs Poulsen et al.   PLoS One

Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation

(2013) Mainul Husain et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Commentary

(2012) Ulla Vogel   ATHEROSCLEROSIS

Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint

(2012) Anne Saber et al.   Particle and Fibre Toxicology

Hepatic and Pulmonary Toxicogenomic Profiles in Mice Intratracheally Instilled With Carbon Black Nanoparticles Reveal Pulmonary Inflammation, Acute Phase Response, and Alterations in Lipid Homeostasis

(2012) Julie A. Bourdon et al.   TOXICOLOGICAL SCIENCES

Serum amyloid A in atherosclerosis

(2011) Victoria L. King et al.   CURRENT OPINION IN LIPIDOLOGY

Pulmonary response to surface-coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study

(2011) Sabina Halappanavar et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Serum Amyloid A Activates the NLRP3 Inflammasome and Promotes Th17 Allergic Asthma in Mice

(2011) J. L. Ather et al.   JOURNAL OF IMMUNOLOGY

Identification of Systemic Markers from A Pulmonary Carbon Nanotube Exposure

(2011) Aaron Erdely et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

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(2011) Zhe Dong et al.   MOLECULAR MEDICINE

Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers

(2011) Anne Thoustrup Saber et al.   Nanotoxicology

Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA secretory phospholipase A2

(2010) Wijtske Annema et al.   JOURNAL OF LIPID RESEARCH

Inflammation Impairs Reverse Cholesterol Transport In Vivo

(2009) Fiona C. McGillicuddy et al.   CIRCULATION

Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease

(2009) Paul Elliott   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Inflammatory biomarkers in coronary artery disease

(2009) Epaminondas Zakynthinos et al.   Journal of Cardiology

Serum amyloid A is independently associated with metabolic risk factors but not with early atherosclerosis: the Cardiovascular Risk in Young Finns Study

(2009) J. Jylhävä et al.   JOURNAL OF INTERNAL MEDICINE

Effects of inhalable particulate matter on blood coagulation

(2009) M. BONZINI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Lack of acute phase response in the livers of mice exposed to diesel exhaust particles or carbon black by inhalation

(2009) Anne T Saber et al.   Particle and Fibre Toxicology

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

Cross-Talk between Lung and Systemic Circulation during Carbon Nanotube Respiratory Exposure. Potential Biomarkers

(2008) Aaron Erdely et al.   NANO LETTERS

C-Reactive Protein (CRP) Gene Polymorphisms, CRP Levels, and Risk of Incident Coronary Heart Disease in Two Nested Case-Control Studies

(2008) Jennifer K. Pai et al.   PLoS One