Transcriptomic Analysis Reveals Novel Mechanistic Insight into Murine Biological Responses to Multi-Walled Carbon Nanotubes in Lungs and Cultured Lung Epithelial Cells

Toward Correlation in In Vivo and In Vitro Nanotoxicology Studies

(2015) Melissa A. Maurer-Jones et al.   JOURNAL OF LAW MEDICINE & ETHICS

Particle-Induced Pulmonary Acute Phase Response Correlates with Neutrophil Influx Linking Inhaled Particles and Cardiovascular Risk

(2013) Anne Thoustrup Saber et al.   PLoS One

A global toxicogenomic analysis investigating the mechanistic differences between tobacco and marijuana smoke condensates in vitro

(2013) Rebecca M. Maertens et al.   TOXICOLOGY

Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation

(2013) Mainul Husain et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice

(2012) Atsuya Takagi et al.   CANCER SCIENCE

Genetic toxicology and toxicogenomic analysis of three cigarette smoke condensates in vitro reveals few differences among full-flavor, blonde, and light products

(2012) Carole L. Yauk et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

New Perspectives for in Vitro Risk Assessment of Multiwalled Carbon Nanotubes: Application of Coculture and Bioinformatics

(2012) Brandi N. Snyder-Talkington et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver

(2012) Julie A Bourdon et al.   Particle and Fibre Toxicology

Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint

(2012) Anne Saber et al.   Particle and Fibre Toxicology

Hepatic and Pulmonary Toxicogenomic Profiles in Mice Intratracheally Instilled With Carbon Black Nanoparticles Reveal Pulmonary Inflammation, Acute Phase Response, and Alterations in Lipid Homeostasis

(2012) Julie A. Bourdon et al.   TOXICOLOGICAL SCIENCES

Assessing the relevance of in vitro studies in nanotoxicology by examining correlations between in vitro and in vivo data

(2012) Xianglu Han et al.   TOXICOLOGY

Dispersal State of Multiwalled Carbon Nanotubes Elicits Profibrogenic Cellular Responses That Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung

(2011) Xiang Wang et al.   ACS Nano

Pulmonary response to surface-coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study

(2011) Sabina Halappanavar et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Evaluation of Acute Oxidative Stress Induced by NiO Nanoparticles In Vivo and In Vitro

(2011) Masanori Horie et al.   JOURNAL OF OCCUPATIONAL HEALTH

Inflammatory and genotoxic effects of sanding dust generated from nanoparticle-containing paints and lacquers

(2011) Anne Thoustrup Saber et al.   Nanotoxicology

Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers

(2011) Anne Thoustrup Saber et al.   Nanotoxicology

Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: Effects on liver DNA strand breaks in dams and offspring

(2011) Petra Jackson et al.   Nanotoxicology

Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes

(2011) Robert R Mercer et al.   Particle and Fibre Toxicology

Multi-Walled Carbon Nanotube Instillation Impairs Pulmonary Function in C57BL/6 Mice

(2011) Xiaojia Wang et al.   Particle and Fibre Toxicology

Adverse Effect of Nano-Silicon Dioxide on Lung Function of Rats with or without Ovalbumin Immunization

(2011) Bing Han et al.   PLoS One

A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity

(2010) Helinor J. Johnston et al.   CRITICAL REVIEWS IN TOXICOLOGY

Review of carbon nanotubes toxicity and exposure—Appraisal of human health risk assessment based on open literature

(2010) Karin Aschberger et al.   CRITICAL REVIEWS IN TOXICOLOGY

Mutation spectrum in FE1-MUTATMMouse lung epithelial cells exposed to nanoparticulate carbon black

(2010) Nicklas Raun Jacobsen et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Pulmonary toxicity assessment of multiwalled carbon nanotubes in rats following intratracheal instillation

(2010) A. Rama Narsimha Reddy et al.   ENVIRONMENTAL TOXICOLOGY

Carbon Nanotubes Elicit DNA Damage and Inflammatory Response Relative to Their Size and Shape

(2010) Kohei Yamashita et al.   INFLAMMATION

A critical review of the biological mechanisms underlying thein vivoandin vitrotoxicity of carbon nanotubes: The contribution of physico-chemical characteristics

(2010) Helinor J. Johnston et al.   Nanotoxicology

Multi-walled carbon nanotubes (Baytubes®): Approach for derivation of occupational exposure limit

(2010) Jürgen Pauluhn   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The Impact of Toxicity Testing Costs on Nanomaterial Regulation

(2009) Jae-Young Choi et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Nanoscale and Fine Zinc Oxide Particles: Can in Vitro Assays Accurately Forecast Lung Hazards following Inhalation Exposures?

(2009) D. B. Warheit et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The status ofin vitrotoxicity studies in the risk assessment of nanomaterials

(2009) Margriet VDZ Park et al.   Nanomedicine

Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

(2009) Nicklas Jacobsen et al.   Particle and Fibre Toxicology

Transcriptional responses to oxidative stress: Pathological and toxicological implications

(2009) Qiang Ma   PHARMACOLOGY & THERAPEUTICS

Subchronic 13-Week Inhalation Exposure of Rats to Multiwalled Carbon Nanotubes: Toxic Effects Are Determined by Density of Agglomerate Structures, Not Fibrillar Structures

(2009) Jürgen Pauluhn   TOXICOLOGICAL SCIENCES

Inhalation Toxicity of Multiwall Carbon Nanotubes in Rats Exposed for 3 Months

(2009) Lan Ma-Hock et al.   TOXICOLOGICAL SCIENCES

Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes

(2009) Dale W. Porter et al.   TOXICOLOGY

Global transcriptional characterization of a mouse pulmonary epithelial cell line for use in genetic toxicology

(2009) M. Lynn Berndt-Weis et al.   TOXICOLOGY IN VITRO

Influenza A Virus Inhibits Alveolar Fluid Clearance in BALB/c Mice

(2008) Kendra E. Wolk et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Monitoring Multiwalled Carbon Nanotube Exposure in Carbon Nanotube Research Facility

(2008) Jeong Hee Han et al.   INHALATION TOXICOLOGY

Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube

(2008) Atsuya Takagi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in Muta™Mouse and lung epithelial cells derived from Muta™Mouse

(2008) Volker M. Arlt et al.   MUTAGENESIS

Diesel exhaust particles are mutagenic in FE1-Muta™Mouse lung epithelial cells

(2008) Nicklas Raun Jacobsen et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Single-Walled Carbon Nanotubes Can Induce Pulmonary Injury in Mouse Model

(2008) Cheng-Chung Chou et al.   NANO LETTERS

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology

Role of mechanical stress in regulating airway surface hydration and mucus clearance rates

(2008) Brian Button et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY