Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation

Incidence of hospitalisation for severe complications of influenza virus infection in Japanese patients between 2012 and 2016: a cross-sectional study using routinely collected administrative data

(2019) Hiroshi Yokomichi et al.   BMJ Open

IFITM3: How genetics influence influenza infection demographically

(2019) Dannielle Wellington et al.   Biomedical Journal

Proteostasis in Viral Infection: Unfolding the Complex Virus–Chaperone Interplay

(2019) Ranen Aviner et al.   Cold Spring Harbor Perspectives in Biology

Transmission of α-synuclein seeds in neurodegenerative disease: recent developments

(2019) Richard J. Karpowicz et al.   LABORATORY INVESTIGATION

Seeding Variability of Different Alpha Synuclein Strains in Synucleinopathies

(2019) Niccolò Candelise et al.   ANNALS OF NEUROLOGY

How is alpha‐synuclein cleared from the cell?

(2019) Leonidas Stefanis et al.   JOURNAL OF NEUROCHEMISTRY

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

(2019) Sangjune Kim et al.   NEURON

Alpha-synuclein: prion or prion-like?

(2019) Rehana K. Leak et al.   ACTA NEUROPATHOLOGICA

Protein misassembly and aggregation as potential convergence points for non-genetic causes of chronic mental illness

(2018) Nicholas J. Bradshaw et al.   MOLECULAR PSYCHIATRY

Influenza A Virus NS1 Protein Suppresses JNK1-Dependent Autophagosome Formation Mediated by Rab11a Recycling Endosomes

(2018) Takahiro Kuroki et al.   Frontiers in Microbiology

Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method

(2017) Dan Dou et al.   Cell Reports

α-Synuclein: Multiple System Atrophy Prions

(2017) Amanda L. Woerman et al.   Cold Spring Harbor Perspectives in Medicine

Transfer of disrupted-in-schizophrenia 1 aggregates between neuronal-like cells occurs in tunnelling nanotubes and is promoted by dopamine

(2017) Seng Zhu et al.   Open Biology

Host proteostasis modulates influenza evolution

(2017) Angela M Phillips et al.   eLife

The Dynamics and Turnover of Tau Aggregates in Cultured Cells

(2016) Jing L. Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease

(2016) Nolwen L. Rey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits

(2016) S V Trossbach et al.   MOLECULAR PSYCHIATRY

Opportunistic intruders: how viruses orchestrate ER functions to infect cells

(2016) Madhu Sudhan Ravindran et al.   NATURE REVIEWS MICROBIOLOGY

In vivo aspects of protein folding and quality control

(2016) D. Balchin et al.   SCIENCE

H1N1 influenza virus induces narcolepsy-like sleep disruption and targets sleep–wake regulatory neurons in mice

(2015) Chiara Tesoriero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral capsid assembly as a model for protein aggregation diseases: Active processes catalyzed by cellular assembly machines comprising novel drug targets

(2015) Rita Marreiros et al.   VIRUS RESEARCH

Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection

(2015) Frank S. Heldt et al.   Nature Communications

Alpha-synuclein degradation by autophagic pathways: A potential key to Parkinson’s Disease pathogenesis

(2014) Maria Xilouri et al.   Autophagy

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

(2014) E. L. Scotter et al.   JOURNAL OF CELL SCIENCE

The olfactory nerve: a shortcut for influenza and other viral diseases into the central nervous system

(2014) Debby van Riel et al.   JOURNAL OF PATHOLOGY

An updated systematic review of the role of host genetics in susceptibility to influenza

(2013) Peter Horby et al.   Influenza and Other Respiratory Viruses

Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy

(2013) Selcuk A. Tanik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Host-rabies virus protein-protein interactions as druggable antiviral targets

(2013) U. F. Lingappa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System

(2012) Hwan-Ching Tai et al.   AMERICAN JOURNAL OF PATHOLOGY

A Population-Based Study of Neurologic Manifestations of Severe Influenza A(H1N1)pdm09 in California

(2012) C. A. Glaser et al.   CLINICAL INFECTIOUS DISEASES

The DISC1 promoter: characterization and regulation by FOXP2

(2012) Rosie M. Walker et al.   HUMAN MOLECULAR GENETICS

Disrupted in Schizophrenia 1 forms pathological aggresomes that disrupt its function in intracellular transport

(2012) Talia A. Atkin et al.   HUMAN MOLECULAR GENETICS

Infections as a risk factor for Parkinson's disease: a case–control study

(2012) Hristina Vlajinac et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

(2012) Kelvin C. Luk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Disrupted Autophagy Leads to Dopaminergic Axon and Dendrite Degeneration and Promotes Presynaptic Accumulation of  -Synuclein and LRRK2 in the Brain

(2012) L. G. Friedman et al.   JOURNAL OF NEUROSCIENCE

Systematic Mutagenesis of  -Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities

(2012) J. Burre et al.   JOURNAL OF NEUROSCIENCE

Association of Parkinson's disease with infections and occupational exposure to possible vectors

(2012) M. Anne Harris et al.   MOVEMENT DISORDERS

Convergence of Two Independent Mental Disease Genes on the Protein Level: Recruitment of Dysbindin to Cell-Invasive Disrupted-In-Schizophrenia 1 Aggresomes

(2011) Philipp Ottis et al.   BIOLOGICAL PSYCHIATRY

Parkinson’s disease or Parkinson symptoms following seasonal influenza

(2011) Stephen Toovey et al.   Influenza and Other Respiratory Viruses

The Virulence of 1997 H5N1 Influenza Viruses in the Mouse Model Is Increased by Correcting a Defect in Their NS1 Proteins

(2011) A. Spesock et al.   JOURNAL OF VIROLOGY

Subclinical Brain Injury Caused by H5N1 Influenza Virus Infection

(2011) K. Shinya et al.   JOURNAL OF VIROLOGY

Autopsy series of 68 cases dying before and during the 1918 influenza pandemic peak

(2011) Z.-M. Sheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A historical analysis of the relationship between encephalitis lethargica and postencephalitic parkinsonism: A complex rather than a direct relationship

(2010) Joel A. Vilensky et al.   MOVEMENT DISORDERS

Absence of α-synuclein pathology in postencephalitic parkinsonism

(2009) Kurt A. Jellinger   ACTA NEUROPATHOLOGICA

Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes

(2009) Monique Gannagé et al.   Cell Host & Microbe

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration

(2009) H. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insolubility of Disrupted-in-Schizophrenia 1 Disrupts Oligomer-Dependent Interactions with Nuclear Distribution Element 1 and Is Associated with Sporadic Mental Disease

(2008) S. R. Leliveld et al.   JOURNAL OF NEUROSCIENCE